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1. Effects of comprehensive, individualized, person‐centered care on the relative risks of hospitalization and emergency department visits in community‐dwelling persons with advanced Alzheimer’s Disease in a 52‐week randomized controlled trial

Author

Kenowsky, Sunnie, primary, Shao, Yongzhao, additional, Heller, Sloane, additional, Dafflisio, Gianna, additional, Vedvyas, Alok, additional, Marsh, Karyn, additional, Romero, Arelis, additional, Talbeh, Mahmoud, additional, Sadowski, Martin J., additional, Masurkar, Arjun V., additional, and Reisberg, Barry, additional

Published
2023
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4. Functional Outcomes of a Comprehensive, Individualized, Person‐Centered Management Program in Advanced Alzheimer’s Disease(AD): Results from a 52‐Week Randomized Controlled Trial

Author

Kenowsky, Sunnie, primary, Shao, Yongzhao, additional, Zhang, Qiao, additional, Dafflisio, Gianna, additional, Vedvyas, Alok, additional, Vedvyas, Gaurav, additional, Golomb, James B., additional, Torossian, Carol, additional, Marsh, Karyn, additional, Heller, Sloane, additional, Sadowski, Martin J., additional, and Reisberg, Barry, additional

Published
2022
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5. Functional Outcomes of a Comprehensive, Individualized, Person‐Centered Management Program in Advanced Alzheimer’s Disease(AD): Results from a 52‐Week Randomized Controlled Trial

Author

Sunnie Kenowsky, Yongzhao Shao, Qiao Zhang, Gianna Dafflisio, Alok Vedvyas, Gaurav Vedvyas, James B. Golomb, Carol Torossian, Karyn Marsh, Sloane Heller, Martin J. Sadowski, and Barry Reisberg

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2022
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6. Comparison of serum neurodegenerative biomarkers among hospitalized COVID‐19 patients versus non‐COVID subjects with normal cognition, mild cognitive impairment, or Alzheimer's dementia

Author

Jennifer A. Frontera, Allal Boutajangout, Arjun V. Masurkar, Rebecca A. Betensky, Yulin Ge, Alok Vedvyas, Ludovic Debure, Andre Moreira, Ariane Lewis, Joshua Huang, Sujata Thawani, Laura Balcer, Steven Galetta, and Thomas Wisniewski

Subjects
Amyloid beta-Peptides, Epidemiology, Health Policy, COVID-19, tau Proteins, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Cognition, Developmental Neuroscience, Alzheimer Disease, Humans, Cognitive Dysfunction, Hospital Mortality, Neurology (clinical), Geriatrics and Gerontology, Biomarkers
Abstract

Neurological complications among hospitalized COVID-19 patients may be associated with elevated neurodegenerative biomarkers.Among hospitalized COVID-19 patients without a history of dementia (N = 251), we compared serum total tau (t-tau), phosphorylated tau-181 (p-tau181), glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), ubiquitin carboxy-terminal hydrolase L1 (UCHL1), and amyloid beta (Aβ40,42) between patients with or without encephalopathy, in-hospital death versus survival, and discharge home versus other dispositions. COVID-19 patient biomarker levels were also compared to non-COVID cognitively normal, mild cognitive impairment (MCI), and Alzheimer's disease (AD) dementia controls (N = 161).Admission t-tau, p-tau181, GFAP, and NfL were significantly elevated in patients with encephalopathy and in those who died in-hospital, while t-tau, GFAP, and NfL were significantly lower in those discharged home. These markers correlated with severity of COVID illness. NfL, GFAP, and UCHL1 were higher in COVID patients than in non-COVID controls with MCI or AD.Neurodegenerative biomarkers were elevated to levels observed in AD dementia and associated with encephalopathy and worse outcomes among hospitalized COVID-19 patients.

Published
2022
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11. Effect of comprehensive, individualized, person‐centered management (CI‐PCM) on psychotropic medication usage in advanced Alzheimer’s persons in a 28‐week randomized controlled trial

Author

Sunnie Kenowsky, Yongzhao Shao, Jia Bao, Carol Torossian, Gianna Dafflisio, Alok Vedvyas, and Barry Reisberg

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2021
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13. Comparison of serum neurodegenerative biomarkers among hospitalized COVID‐19 patients versus non‐COVID subjects with normal cognition, mild cognitive impairment, or Alzheimer's dementia

Author

Frontera, Jennifer A., primary, Boutajangout, Allal, additional, Masurkar, Arjun V., additional, Betensky, Rebecca A., additional, Ge, Yulin, additional, Vedvyas, Alok, additional, Debure, Ludovic, additional, Moreira, Andre, additional, Lewis, Ariane, additional, Huang, Joshua, additional, Thawani, Sujata, additional, Balcer, Laura, additional, Galetta, Steven, additional, and Wisniewski, Thomas, additional

Published
2022
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17. Hydroxylamine-O -Sulfonic Acid (HOSA) as a Redox-Neutral Directing Group: Rhodium Catalyzed, Additive Free, One-Pot Synthesis of Isoquinolines from Arylketones

Author

Pragati Biswal, Rajesh Chebolu, Asit Ghosh, Ponneri Chandrababu Ravikumar, and Bedadyuti Vedvyas Pati

Subjects
chemistry.chemical_compound, Hydroxylamine-O-sulfonic acid, Group (periodic table), Chemistry, Organic Chemistry, One-pot synthesis, chemistry.chemical_element, Physical and Theoretical Chemistry, Isoquinoline, Redox, Medicinal chemistry, Catalysis, Rhodium
Published
2020
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18. Effect of comprehensive, individualized, person‐centered management on antidepressant usage in advanced Alzheimer’s persons in a 28‐week, randomized, controlled trial

Author

Carol Torossian, Sunnie Kenowsky, Yongzhao Shao, Alok Vedvyas, Barry Reisberg, Muhammad Saad, and Gianna Dafflisio

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Person centered, law.invention, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Randomized controlled trial, law, Physical therapy, Medicine, Antidepressant, Neurology (clinical), Geriatrics and Gerontology, business
Published
2020
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19. Associations between subjective cognitive decline (SCD) diagnosis and severity with plasma tau and NfL levels using SIMOA technology

Author

Arjun V. Masurkar, Thomas Wisniewski, Dishari Zaman Azad, Alok Vedvyas, Ricardo S Osorio, Ludovic Debure, and Yongzhao Shao

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, business.industry, Health Policy, Medicine, Neurology (clinical), Geriatrics and Gerontology, Cognitive decline, business, Clinical psychology
Published
2020
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23. F3‐03‐04: COMPREHENSIVE, INDIVIDUALIZED, PERSON‐CENTERED MANAGEMENT PROGRAM REDUCES RISK OF HOSPITALIZATION BY 67% AND EMERGENCY ROOM VISITS BY 50% IN COMMUNITY‐RESIDING, ADVANCED AD PERSONS IN A 28‐WEEK RANDOMIZED, CONTROLLED TRIAL

Author

Munther Alshalabi, Barry Reisberg, Gianna Dafflisio, Alok Vedvyas, Kathryn Sommese, Sunnie Kenowsky, Yongzhao Shao, and Sloane Heller

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Person centered, law.invention, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Randomized controlled trial, law, Physical therapy, Medicine, Neurology (clinical), Geriatrics and Gerontology, business
Published
2018
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24. O2-11-03: BEHAVIORAL SYMPTOMS ARE A HARBINGER OF FURTHER COGNITIVE DECLINE IN A 2-YEAR LONGITUDINAL STUDY OF PERSONS WITH SUBJECTIVE COGNITIVE DECLINE (SCD)

Author

Sunnie Kenowsky, Yongzhao Shao, Yian Zhang, Fauzia Arain, Barry Reisberg, Alok Vedvyas, and Maja Buj

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Longitudinal study, Developmental Neuroscience, Epidemiology, business.industry, Health Policy, Medicine, Neurology (clinical), Geriatrics and Gerontology, Cognitive decline, business, Clinical psychology
Published
2019
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26. F3‐03‐04: COMPREHENSIVE, INDIVIDUALIZED, PERSON‐CENTERED MANAGEMENT PROGRAM REDUCES RISK OF HOSPITALIZATION BY 67% AND EMERGENCY ROOM VISITS BY 50% IN COMMUNITY‐RESIDING, ADVANCED AD PERSONS IN A 28‐WEEK RANDOMIZED, CONTROLLED TRIAL

Author

Kenowsky, Sunnie, primary, Shao, Yongzhao, additional, Sommese, Kathryn, additional, Alshalabi, Munther, additional, Heller, Sloane, additional, Dafflisio, Gianna, additional, Vedvyas, Alok, additional, and Reisberg, Barry, additional

Published
2018
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27. P1–374: Memantine and comprehensive, individualized, person‐centered management (CI‐PCM) of Alzheimer's disease: A randomized controlled trial

Author

Manoj Kumar, Istvan Boksay, Barry Reisberg, Marwa Salam, Santosh Ghimire, James Golomb, Alok Vedvyas, Sunnie Kenowsky, Sadia Qureshi, Carol Torossian, and Sloane Heller

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Memantine, Person centered, Disease, law.invention, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Randomized controlled trial, law, Physical therapy, medicine, Neurology (clinical), Geriatrics and Gerontology, business, medicine.drug
Published
2013
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28. P3–097: Classifying Alzheimer's disease through multigene expression signature profiling

Author

Jaclyn Cocchiola, Thet Oo, Alok Vedvyas, Laura L. Read, Robyn Waters, James D. Clelland, Steven H. Ferris, and Catherine L. Clelland

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Multigene expression, Developmental Neuroscience, Epidemiology, Health Policy, Profiling (information science), Neurology (clinical), Disease, Computational biology, Geriatrics and Gerontology, Biology
Published
2006
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29. P1–374: Memantine and comprehensive, individualized, person‐centered management (CI‐PCM) of Alzheimer's disease: A randomized controlled trial

Author

Reisberg, Barry, primary, Kenowsky, Sunnie, additional, Boksay, Istvan, additional, Golomb, James, additional, Heller, Sloane, additional, Ghimire, Santosh, additional, Salam, Marwa, additional, Qureshi, Sadia, additional, Kumar, Manoj, additional, Torossian, Carol, additional, and Vedvyas, Alok, additional

Published
2013
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30. The pre–mild cognitive impairment, subjective cognitive impairment stage of Alzheimer's disease

Author

Reisberg, Barry, primary, Prichep, Leslie, additional, Mosconi, Lisa, additional, John, E. Roy, additional, Glodzik‐Sobanska, Lidia, additional, Boksay, Istvan, additional, Monteiro, Isabel, additional, Torossian, Carol, additional, Vedvyas, Alok, additional, Ashraf, Nauman, additional, Jamil, Imran A., additional, and Leon, Mony J., additional

Published
2008
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