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Your search keyword '"Unger, Ron"' showing total 18 results
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18 results on '"Unger, Ron"'

1. Pseudouridines on Trypanosoma brucei mRNAs are developmentally regulated: Implications to mRNA stability and protein binding

Author

Rajan, K. Shanmugha, primary, Adler, Katerina, additional, Madmoni, Hava, additional, Peleg‐Chen, Dana, additional, Cohen‐Chalamish, Smadar, additional, Doniger, Tirza, additional, Galili, Beathrice, additional, Gerber, Doron, additional, Unger, Ron, additional, Tschudi, Christian, additional, and Michaeli, Shulamit, additional

Published
2021
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2. Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges

Author

Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory, Daneshjou, Roxana, Wang, Yanran, Bromberg, Yana, Bovo, Samuele, Martelli, Pier L, Babbi, Giulia, Di Lena, Pietro, Casadio, Rita, Edwards, Matthew D, Gifford, David K, Jones, David T, Sundaram, Laksshman, Bhat, Rajendra, Li, Xiaolin, Pal, Lipika R., Kundu, Kunal, Yin, Yizhou, Moult, John, Jiang, Yuxiang, Pejaver, Vikas, Pagel, Kymberleigh A., Li, Biao, Mooney, Sean D., Radivojac, Predrag, Shah, Sohela, Carraro, Marco, Gasparini, Alessandra, Leonardi, Emanuela, Giollo, Manuel, Ferrari, Carlo, Tosatto, Silvio C E, Bachar, Eran, Azaria, Johnathan R., Ofran, Yanay, Unger, Ron, Niroula, Abhishek, Vihinen, Mauno, Chang, Billy, Wang, Maggie H, Franke, Andre, Petersen, Britt-Sabina, Pirooznia, Mehdi, Zandi, Peter, McCombie, Richard, Potash, James B, Altman, Russ, Klein, Teri E., Hoskins, Roger, Repo, Susanna, Brenner, Steve E, Morgan, Alexander A, Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory, Daneshjou, Roxana, Wang, Yanran, Bromberg, Yana, Bovo, Samuele, Martelli, Pier L, Babbi, Giulia, Di Lena, Pietro, Casadio, Rita, Edwards, Matthew D, Gifford, David K, Jones, David T, Sundaram, Laksshman, Bhat, Rajendra, Li, Xiaolin, Pal, Lipika R., Kundu, Kunal, Yin, Yizhou, Moult, John, Jiang, Yuxiang, Pejaver, Vikas, Pagel, Kymberleigh A., Li, Biao, Mooney, Sean D., Radivojac, Predrag, Shah, Sohela, Carraro, Marco, Gasparini, Alessandra, Leonardi, Emanuela, Giollo, Manuel, Ferrari, Carlo, Tosatto, Silvio C E, Bachar, Eran, Azaria, Johnathan R., Ofran, Yanay, Unger, Ron, Niroula, Abhishek, Vihinen, Mauno, Chang, Billy, Wang, Maggie H, Franke, Andre, Petersen, Britt-Sabina, Pirooznia, Mehdi, Zandi, Peter, McCombie, Richard, Potash, James B, Altman, Russ, Klein, Teri E., Hoskins, Roger, Repo, Susanna, Brenner, Steve E, and Morgan, Alexander A

Abstract

Precision medicine aims to predict a patient's disease risk and best therapeutic options by using that individual's genetic sequencing data. The Critical Assessment of Genome Interpretation (CAGI) is a community experiment consisting of genotype–phenotype prediction challenges; participants build models, undergo assessment, and share key findings. For CAGI 4, three challenges involved using exome-sequencing data: Crohn's disease, bipolar disorder, and warfarin dosing. Previous CAGI challenges included prior versions of the Crohn's disease challenge. Here, we discuss the range of techniques used for phenotype prediction as well as the methods used for assessing predictive models. Additionally, we outline some of the difficulties associated with making predictions and evaluating them. The lessons learned from the exome challenges can be applied to both research and clinical efforts to improve phenotype prediction from genotype. In addition, these challenges serve as a vehicle for sharing clinical and research exome data in a secure manner with scientists who have a broad range of expertise, contributing to a collaborative effort to advance our understanding of genotype–phenotype relationships.

Published
2021

3. Cervical dilation at the time of epidural catheter insertion is not associated with the degree of prolongation of the first or second stages of labor, or the rate of instrumental vaginal delivery

Author

Lipschuetz, Michal, primary, Nir, Eshel A., additional, Cohen, Sarah M., additional, Guedalia, Joshua, additional, Hochler, Hila, additional, Amsalem, Hagai, additional, Karavani, Gilad, additional, Hochner‐Celnikier, Drorith, additional, Unger, Ron, additional, and Yagel, Simcha, additional

Published
2020
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4. Validation of the acute leukemia‐EBMT score for prediction of mortality following allogeneic stem cell transplantation in a multi‐center GITMO cohort

Author

Shouval, Roni, primary, Bonifazi, Francesca, additional, Fein, Joshua, additional, Boschini, Cristina, additional, Oldani, Elena, additional, Labopin, Myriam, additional, Raimondi, Roberto, additional, Sacchi, Nicoletta, additional, Dabash, Osamah, additional, Unger, Ron, additional, Mohty, Mohamad, additional, Rambaldi, Alessandro, additional, and Nagler, Arnon, additional

Published
2017
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10. Phenotypic redifferentiation and cell cluster formation of cultured human articular chondrocytes in a three-dimensional oriented gelatin scaffold in the presence of PGE2- first results of a pilot study

Author

Brochhausen, Christoph, primary, Sánchez, Natalia, additional, Halstenberg, Sven, additional, Zehbe, Rolf, additional, Watzer, Bernhard, additional, Schmitt, Volker H., additional, Hofmann, Alexander, additional, Meurer, Andrea, additional, Unger, Ron E., additional, and Kirkpatrick, Charles James, additional

Published
2013
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16. Chaos in protein dynamics

Author

Braxenthaler, Michael, primary, Unger, Ron, additional, Auerbach, Ditza, additional, Given, James A., additional, and Moult, John, additional

Published
1997
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