Search

Your search keyword '"Trask, Jessica Satkoski"' showing total 10 results
Start Over Author "Trask, Jessica Satkoski" Publisher wiley
10 results on '"Trask, Jessica Satkoski"'

1. Ancestry,Plasmodium cynomolgiprevalence and rhesus macaque admixture in cynomolgus macaques (Macaca fascicularis) bred for export in Chinese breeding farms

Author

Zhang, Xinjun, primary, Meng, Yuhuan, additional, Houghton, Paul, additional, Liu, Mingyu, additional, Kanthaswamy, Sreetharan, additional, Oldt, Robert, additional, Ng, Jillian, additional, Trask, Jessica Satkoski, additional, Huang, Ren, additional, Singh, Balbir, additional, Du, Hongli, additional, and Smith, David Glenn, additional

Published
2017
Full Text
View/download PDF

4. Development and validation of a SNP-based assay for inferring the genetic ancestry of rhesus macaques (Macaca mulatta)

Author

Kanthaswamy, Sree, primary, Johnson, Zachary, additional, Trask, Jessica Satkoski, additional, Smith, David G., additional, Ramakrishnan, Ranjani, additional, Bahk, Jason, additional, Ng, Jillian, additional, Wiseman, Roger, additional, Kubisch, H. Michael, additional, Vallender, Eric J., additional, Rogers, Jeffrey, additional, and Ferguson, Betsy, additional

Published
2014
Full Text
View/download PDF

9. Ancestry, Plasmodium cynomolgi prevalence and rhesus macaque admixture in cynomolgus macaques (Macaca fascicularis) bred for export in Chinese breeding farms.

Author

Zhang X, Meng Y, Houghton P, Liu M, Kanthaswamy S, Oldt R, Ng J, Trask JS, Huang R, Singh B, Du H, and Smith DG

Subjects
Animals, China epidemiology, Genetic Markers, Hybridization, Genetic, Macaca mulatta genetics, Malaria parasitology, Monkey Diseases parasitology, Prevalence, Breeding, Macaca fascicularis genetics, Malaria epidemiology, Monkey Diseases epidemiology, Plasmodium cynomolgi isolation & purification, Polymorphism, Single Nucleotide
Abstract

Background: Most cynomolgus macaques (Macaca fascicularis) used in the United States as animal models are imported from Chinese breeding farms without documented ancestry. Cynomolgus macaques with varying rhesus macaque ancestry proportions may exhibit differences, such as susceptibility to malaria, that affect their suitability as a research model., Methods: DNA of 400 cynomolgus macaques from 10 Chinese breeding farms was genotyped to characterize their regional origin and rhesus ancestry proportion. A nested PCR assay was used to detect Plasmodium cynomolgi infection in sampled individuals., Results: All populations exhibited high levels of genetic heterogeneity and low levels of inbreeding and genetic subdivision. Almost all individuals exhibited an Indochinese origin and a rhesus ancestry proportion of 5%-48%. The incidence of P. cynomolgi infection in cynomolgus macaques is strongly associated with proportion of rhesus ancestry., Conclusions: The varying amount of rhesus ancestry in cynomolgus macaques underscores the importance of monitoring their genetic similarity in malaria research., (© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Published
2017
Full Text
View/download PDF

10. Expression levels of 10 candidate genes in lung tissue of vaccinated and TB-infected cynomolgus macaques.

Author

Roodgar M, Lackner A, Kaushal D, Sankaran S, Dandekar S, Trask JS, Drake C, and Smith DG

Subjects
Animals, Cytokines genetics, Cytokines metabolism, DNA, Complementary genetics, DNA, Complementary metabolism, Lung immunology, Lung microbiology, Lymph Nodes immunology, Mycobacterium tuberculosis physiology, Nitric Oxide Synthase Type II genetics, Nitric Oxide Synthase Type II metabolism, Polymorphism, Single Nucleotide, RNA, Messenger genetics, RNA, Messenger metabolism, Real-Time Polymerase Chain Reaction, Toll-Like Receptors genetics, Toll-Like Receptors metabolism, Tuberculosis, Pulmonary microbiology, BCG Vaccine immunology, Disease Models, Animal, Gene Expression Regulation, Macaca fascicularis, Tuberculosis, Pulmonary genetics, Tuberculosis, Pulmonary immunology
Abstract

The expression of ten tuberculosis candidate genes in lung and lymph nodes of cynomolgus macaques vaccinated and experimentally infected with Mycobacterium tuberculosis (Mtb) was quantified. The expression of TNFα, IL10, IL1β, TLR4, IL17, IL6, IL12, and iNOS in the lungs of vaccinated animals was higher than that of non-vaccinated animals.

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results