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18 results on '"Su, Xuan"'

2. Establishment of an in‐house real‐time RT‐PCR assay for the detection of severe acute respiratory syndrome coronavirus 2 using the first World Health Organization international standard in a resource‐limited country

Author

Nguyen, Linh Tung, Nguyen, Phuong Minh, Dinh, Duc Viet, Pham, Hung Ngoc, Bui, Lan Anh Thi, Vo, Cuong Viet, Nguyen, Ben Huu, Bui, Hoan Duy, Hoang, Cuong Xuan, Ngo, Nhat Minh Van, Dang, Truong Tien, Do, Anh Ngoc, Vu, Dung Dinh, Nguyen, Linh Thuy, Nguyen, Mai Ngoc, Dinh, Thu Hang Thi, Ho, Son Anh, Hoang, Luong Van, Hoang, Su Xuan, and Do, Quyet

Subjects
Microbiology (medical), Reverse Transcriptase Polymerase Chain Reaction, SARS-CoV-2, Biochemistry (medical), Clinical Biochemistry, Public Health, Environmental and Occupational Health, COVID-19, Hematology, World Health Organization, Sensitivity and Specificity, Medical Laboratory Technology, Nasopharynx, Humans, Immunology and Allergy, Pandemics
Abstract

The COVID-19 pandemic caused by SARS-CoV-2 remains public health burdens and many unresolved issues worldwide. Molecular assays based on real-time RT-PCR are critical for the detection of SARS-CoV-2 in clinical specimens from patients suspected of COVID-19.We aimed to establish and validate an in-house real-time RT-PCR for the detection of SARS-CoV-2.Primers and probes sets in our in-house real-time RT-PCR assay were designed in conserved regions of the N and E target genes. Optimized multiplex real-time RT-PCR assay was validated using the first WHO International Standard (NIBSC code: 20/146) and evaluated clinical performance.The limit of detection validated using the first WHO International Standard was 159 IU/ml for both E and N target genes. The evaluation of clinical performance on 170 clinical samples showed a positive percent agreement of 100% and the negative percent agreement of 99.08% for both target genes. The Kappa value of 0.99 was an excellent agreement, the strong correlation of CIn the present study, we established and validated an in-house real-time RT-PCR for molecular detection of SARS-CoV-2 in a resource-limited country.

Published
2022

3. The Molecular Ordering and Double‐Channel Carrier Generation of Nonfullerene Photovoltaics within Multi‐Length‐Scale Morphology

Author

Xu, Jinqiu, primary, Jo, Sae Byeok, additional, Chen, Xiankai, additional, Zhou, Guanqing, additional, Zhang, Ming, additional, Shi, Xueliang, additional, Lin, Francis, additional, Zhu, Lei, additional, Hao, Tianyu, additional, Gao, Ke, additional, Zou, Yecheng, additional, Su, Xuan, additional, Feng, Wei, additional, Jen, Alex K.‐Y., additional, Zhang, Yongming, additional, and Liu, Feng, additional

Published
2022
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5. Slot‐Die‐Coated Organic Solar Cells Optimized through Multistep Crystallization Kinetics

Author

Xu, Jinqiu, primary, Zhan, Junzhe, additional, Zhou, Guanqing, additional, Zhong, Wenkai, additional, Zhang, Ming, additional, Xue, Xiaonan, additional, Zhu, Lei, additional, Leng, Shifeng, additional, Chen, Jiajun, additional, Zou, Yecheng, additional, Su, Xuan, additional, Shi, Zhiwen, additional, Zhu, Haiming, additional, Zhang, Maojie, additional, Chen, Chun-Chao, additional, Li, Yongfang, additional, Zhang, Yongming, additional, and Liu, Feng, additional

Published
2022
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6. Association of triglyceride glucose index and its combination of obesity indices with prehypertension in lean individuals: A cross‐sectional study of Chinese adults

Author

Hao Xu, Xia Xu, Zhen Yu Zeng, Xing Zhen Liu, Su Xuan Liu, and Xian Xian Zhao

Subjects
Adult, Blood Glucose, Male, China, Waist, Endocrinology, Diabetes and Metabolism, Population, 030204 cardiovascular system & hematology, Prehypertension, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Risk Factors, Internal Medicine, medicine, Humans, Obesity, 030212 general & internal medicine, education, Triglycerides, education.field_of_study, business.industry, medicine.disease, Cross-Sectional Studies, Glucose, Blood pressure, Quartile, Hypertension, Female, Cardiology and Cardiovascular Medicine, business, Body mass index, Demography
Abstract

For normal‐weight population, the management of prehypertension may be more beneficial by identifying insulin resistance (IR) status than relying solely on traditional indicators of obesity. We investigated the association of triglyceride glucose (TyG) index, a simple surrogate marker of IR, and its combination of obesity indices with prehypertension in lean individuals. A total of 105 070 lean adults without hypertension were included in this analysis. Body mass index (BMI), waist circumference (WC), waist‐to‐height ratio (WtHR), and TyG were calculated according to the corresponding formula; TyG‐BMI, TyG‐WC, and TyG‐WHtR were calculated by multiplying the corresponding two parameters. Gardner‐Altman plots, partial correlation, and logistic regression analyses were applied to explore the associations in continuous variables and quartiles. The prehypertensive ones had higher mean values of TyG, TyG‐BMI, TyG‐WC, and TyG‐WHtR than normotensive individuals. All the four indicators showed positive correlations with systolic blood pressure and diastolic blood pressure. After full adjustment, only TyG‐BMI and TyG‐WC were significantly associated with prehypertension in both genders. Furthermore, TyG‐BMI had the highest OR for prehypertension. Our study showed that TyG‐BMI might be an accessible and complementary monitor in the hierarchical management of non‐obese prehypertensive patients.

Published
2020

7. Manipulating the Crystalline Morphology in the Nonfullerene Acceptor Mixture to Improve the Carrier Transport and Suppress the Energetic Disorder

Author

Zhang, Ming, primary, Zhu, Lei, additional, Qiu, Chaoqun, additional, Hao, Tianyu, additional, Jiang, Yufeng, additional, Leng, Shifeng, additional, Chen, Jiajun, additional, Zhou, Guanqing, additional, Zhou, Zichun, additional, Zou, Yecheng, additional, Su, Xuan, additional, Shi, Zhiwen, additional, Zhu, Haiming, additional, Zhang, Yongming, additional, Russell, Thomas P, additional, Zhu, Xiaozhang, additional, and Liu, Feng, additional

Published
2021
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13. Early Detection of Silent Myocardial Impairment in Drug‐Naive Patients With New‐Onset Systemic Lupus Erythematosus

Author

Guo, Qiang, primary, Wu, Lian‐Ming, additional, Wang, Zi, additional, Shen, Jia‐Yan, additional, Su, Xuan, additional, Wang, Chang‐Qian, additional, Gong, Xing‐Rong, additional, Yan, Qing‐Ran, additional, He, Qing, additional, Zhang, Wei, additional, Xu, Jian‐Rong, additional, Jiang, Meng, additional, and Pu, Jun, additional

Published
2018
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18. Incidence of chromosomal anomalies in fetuses with isolated right aortic arch: A meta-analysis.

Author

Luo Q, Chen J, Zhang Y, Li J, Su X, Wang Q, and Ding Y

Subjects
Chromosome Deletion, Chromosomes, Human, Pair 22 genetics, Female, Humans, Karyotyping, Microarray Analysis, Pregnancy, Prenatal Diagnosis methods, Vascular Ring diagnosis, Chromosome Aberrations statistics & numerical data, Vascular Ring genetics
Abstract

Objective: Right aortic arch (RAA) can be associated with chromosomal anomalies. However, the incidence of chromosomal anomalies when RAA is isolated (iRAA), ie, not associated with intracardiac anomalies, varies between different studies (0%-28.5%). We have performed a meta-analysis to allow a more accurate prenatal counselling., Methods: We searched PubMed, Embase, and Web of Science for articles related to chromosomal anomalies among iRAA fetuses until April 2019. A total of 22 relevant studies, including 670 fetuses, were selected in the final meta-analysis., Results: The results revealed that the overall rates of chromosomal anomalies and 22q11.2 deletion in iRAA fetuses were 7.5% (95% confidence interval [CI], 4.7%-10.8%) and 4.3% (95% CI, 2.6%-6.4%), respectively, while the rates were lower in iRAA without extracardiac anomalies, 4.7% (95% CI, 1.1%-10.8%) and 2.4% (95% CI, 0.5%-5.7%). The rate of chromosomal or copy number variants including 22q11.2 deletion identified by chromosomal microarray analysis (CMA) in iRAA fetuses was 8.2% (95% CI, 5.0%-12.1%) and 3.7% (95% CI, 1.7%-6.6%), respectively, compared with 5.1% (95% CI, 2.5%-8.4%) and 2.4% (95% CI, 0.7%-5.1%) identified by traditional karyotyping., Conclusions: A considerable proportion of iRAA cases have associated chromosomal anomalies and prevalence of associated 22q11.2 deletion, and CMA is recommended if invasive prenatal testing is performed., (© 2019 John Wiley & Sons, Ltd.)

Published
2020
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