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22 results on '"Snively, Beverly"'

2. Analysis of pleiotropic genetic effects on cognitive decline and systemic inflammation in the Women’s Health Initiative Memory Study

Author

Lutz, Michael W, primary, Brown, Mark M., additional, Kucgibhatla, Maragatha, additional, Plassman, Brenda L, additional, Saldana, Santiago, additional, Snively, Beverly M, additional, Chen, Jiu‐Chiuan, additional, Henderson, Victor, additional, Manson, JoAnn E., additional, Pal, Lubna, additional, Shadyab, Aladdin H., additional, Rapp, Stephen R., additional, and Hayden, Kathleen M., additional

Published
2021
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3. Cognitive resilience among APOE ε4 carriers in the oldest old

Author

Hayden, Kathleen M., primary, Gaussoin, Sarah A., additional, Hunter, Jaimie C., additional, Manson, JoAnn E., additional, Sachs, Bonnie C., additional, Shadyab, Aladdin H., additional, Tindle, Hilary A., additional, Mossavar‐Rahmani, Yasmin, additional, Mozhui, Khyobeni, additional, Snively, Beverly M., additional, Rapp, Stephen R., additional, and Resnick, Susan M., additional

Published
2019
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7. A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study

Author

Driscoll, Ira, primary, Snively, Beverly M., additional, Espeland, Mark A., additional, Shumaker, Sally A., additional, Rapp, Stephen R., additional, Goveas, Joseph S., additional, Casanova, Ramon L., additional, Wactawski‐Wende, Jean, additional, Manson, JoAnn E., additional, Rossom, Rebecca, additional, Brooks, Janet, additional, Hernandez, Dena G., additional, Singleton, Andrew B., additional, and Resnick, Susan M., additional

Published
2019
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8. P1‐632: CHARACTERISTICS OF COGNITIVE RESILIENCE IN APOE ε4 CARRIERS AGED 80 AND OLDER: THE WOMEN'S HEALTH INITIATIVE MEMORY STUDY

Author

Hayden, Kathleen M., primary, Gaussoin, Sarah A., additional, Hunter, Jaimie C., additional, Manson, Joann E., additional, Sachs, Bonnie C., additional, Shadyab, Aladdin H., additional, Tindle, Hilary, additional, Mossavar-Rahmani, Yasmin, additional, Mozhui, Khyobeni, additional, Snively, Beverly M., additional, Rapp, Stephen R., additional, and Resnick, Susan M., additional

Published
2018
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11. P4-011: A CANDIDATE GENE STUDY OF GENETIC RISK FOR DEMENTIA AND MILD COGNITIVE IMPAIRMENT (MCI) IN WOMEN AGED >65 YEARS: RESULTS FROM THE WOMEN's HEALTH INITIATIVE MEMORY STUDY (WHIMS)

Author

Driscoll, Ira, primary, Snively, Beverly M., additional, Espeland, Mark A., additional, Shumaker, Sally A., additional, Rapp, Stephen R., additional, Goveas, Joseph S., additional, Casanova, Ramon, additional, Wactawski-Wende, Jean, additional, Manson, JoAnn E., additional, Rossom, Rebecca C., additional, Brooks, Janet, additional, Hernandez, Dena G., additional, Singleton, Andrew B., additional, and Resnick, Susan M., additional

Published
2014
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12. Cognitive impairment in rapid-onset dystonia-parkinsonism

Author

Cook, Jared F., primary, Hill, Deborah F., additional, Snively, Beverly M., additional, Boggs, Niki, additional, Suerken, Cynthia K., additional, Haq, Ihtsham, additional, Stacy, Mark, additional, McCall, W. Vaughn, additional, Ozelius, Laurie J., additional, Sweadner, Kathleen J., additional, and Brashear, Allison, additional

Published
2014
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15. Heritability of serum iron measures in the hemochromatosis and iron overload screening (HEIRS) family study

Author

McLaren, Christine E., primary, Barton, James C., additional, Eckfeldt, John H., additional, McLaren, Gordon D., additional, Acton, Ronald T., additional, Adams, Paul C., additional, Henkin, Leora F., additional, Gordeuk, Victor R., additional, Vulpe, Chris D., additional, Harris, Emily L., additional, Harrison, Barbara W., additional, Reiss, Jacob A., additional, and Snively, Beverly M., additional

Published
2010
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21. GENOME-WIDE ASSOCIATION STUDY (GWAS) AND GENOME-WIDE BY ENVIRONMENT INTERACTION STUDY (GWEIS) OF DEPRESSIVE SYMPTOMS IN AFRICAN AMERICAN AND HISPANIC/LATINA WOMEN.

Author

Dunn EC, Wiste A, Radmanesh F, Almli LM, Gogarten SM, Sofer T, Faul JD, Kardia SL, Smith JA, Weir DR, Zhao W, Soare TW, Mirza SS, Hek K, Tiemeier H, Goveas JS, Sarto GE, Snively BM, Cornelis M, Koenen KC, Kraft P, Purcell S, Ressler KJ, Rosand J, Wassertheil-Smoller S, and Smoller JW

Subjects
Black or African American psychology, Black or African American statistics & numerical data, Aged, Depression psychology, Female, Hispanic or Latino psychology, Hispanic or Latino statistics & numerical data, Humans, Life Change Events, Middle Aged, Phenotype, Polymorphism, Single Nucleotide, Risk Factors, Self Report, Black or African American genetics, Depression genetics, Gene-Environment Interaction, Genome-Wide Association Study statistics & numerical data, Hispanic or Latino genetics
Abstract

Background: Genome-wide association studies (GWAS) have made little progress in identifying variants linked to depression. We hypothesized that examining depressive symptoms and considering gene-environment interaction (GxE) might improve efficiency for gene discovery. We therefore conducted a GWAS and genome-wide by environment interaction study (GWEIS) of depressive symptoms., Methods: Using data from the SHARe cohort of the Women's Health Initiative, comprising African Americans (n = 7,179) and Hispanics/Latinas (n = 3,138), we examined genetic main effects and GxE with stressful life events and social support. We also conducted a heritability analysis using genome-wide complex trait analysis (GCTA). Replication was attempted in four independent cohorts., Results: No SNPs achieved genome-wide significance for main effects in either discovery sample. The top signals in African Americans were rs73531535 (located 20 kb from GPR139, P = 5.75 × 10(-8) ) and rs75407252 (intronic to CACNA2D3, P = 6.99 × 10(-7) ). In Hispanics/Latinas, the top signals were rs2532087 (located 27 kb from CD38, P = 2.44 × 10(-7) ) and rs4542757 (intronic to DCC, P = 7.31 × 10(-7) ). In the GEWIS with stressful life events, one interaction signal was genome-wide significant in African Americans (rs4652467; P = 4.10 × 10(-10) ; located 14 kb from CEP350). This interaction was not observed in a smaller replication cohort. Although heritability estimates for depressive symptoms and stressful life events were each less than 10%, they were strongly genetically correlated (rG = 0.95), suggesting that common variation underlying self-reported depressive symptoms and stressful life event exposure, though modest on their own, were highly overlapping in this sample., Conclusions: Our results underscore the need for larger samples, more GEWIS, and greater investigation into genetic and environmental determinants of depressive symptoms in minorities., (© 2016 Wiley Periodicals, Inc.)

Published
2016
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22. Family history of diabetes, autoimmunity, and risk factors for cardiovascular disease among children with diabetes in the SEARCH for Diabetes in Youth Study.

Author

Gilliam LK, Liese AD, Bloch CA, Davis C, Snively BM, Curb D, Williams DE, and Pihoker C

Subjects
Adolescent, Adult, Age of Onset, Body Weights and Measures, Child, Diabetes Mellitus, Type 1 complications, Diabetes Mellitus, Type 1 epidemiology, Diabetes Mellitus, Type 1 genetics, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 epidemiology, Diabetes Mellitus, Type 2 genetics, Female, Humans, Likelihood Functions, Male, Middle Aged, Risk Factors, Autoimmunity genetics, Cardiovascular Diseases etiology, Diabetes Mellitus, Type 1 etiology, Diabetes Mellitus, Type 2 etiology, Family Health
Abstract

Background: While type 1 diabetes and type 2 diabetes (T2D) are considered etiologically distinct, mixed features of autoimmunity and insulin resistance are increasingly common. We explored a familial contribution to this admixture by evaluating diabetes family history (FH) and its relationship to diabetes type, ethnicity, age at diagnosis, and cardiovascular risk factors in SEARCH for Diabetes in Youth Study participants., Methods: Diabetes FH was assessed by questionnaire, with FH categories defined by relative's(s') age at diagnosis as follows: <25 (early FH), >/=25 (later FH), and both <25 and >/=25 (mixed FH). Diabetes type was classified based on a biochemical algorithm using diabetes autoantibodies and fasting C-peptide (FCP)., Results: A positive FH was common in all diabetes types, particularly T2D (83%). Minorities were more likely to have a positive FH than non-Hispanic Whites [odds ratio (OR) 1.96, 95% confidence interval (CI) 1.69-2.27]. The likelihood of having an early FH decreased with age at diagnosis (OR 0.95, 95% CI 0.93-0.98), and the likelihood of having a later/mixed or any positive FH increased with age (OR 1.03, 95% CI 1.01-1.04; OR 1.03, 95% CI 1.02-1.05, respectively). Higher FCP concentrations and less desirable values for almost all cardiovascular risk factors were associated with a later/mixed FH. The association between a later/mixed FH and FCP, body mass index, waist circumference, triglycerides, and high-density lipoprotein remained significant in a subgroup of autoimmune participants., Conclusions: Later FH confers cardiovascular risk factors in diabetic youth, including those youth with islet cell autoimmunity. This characterization of diabetes FH may provide a better understanding of familial contributors to diabetes.

Published
2007
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