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Your search keyword '"Shu-Yung Chang"' showing total 3 results
Start Over Author "Shu-Yung Chang" Publisher wiley
3 results on '"Shu-Yung Chang"'

3. Neurodevelopmental Defects: A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects (Adv. Sci. 5/2021)

Author

Geetika Sahni, Kagistia Hana Utami, Puck Wee Chan, Thong Teck Tan, Jean Jacques Clement Fatien, Umut Altunoglu, Yi-Chin Toh, Carine Bonnard, Jeremy Teo Choon Meng, Jerome Zu Yao Tan, Bruno Reversade, Hülya Kayserili, Shu-Yung Chang, and Mahmoud A. Pouladi

Subjects
Back Cover, Drug, General Chemical Engineering, media_common.quotation_subject, General Engineering, Neuroepithelial Tissue, General Physics and Astronomy, Medicine (miscellaneous), Biology, Biochemistry, Genetics and Molecular Biology (miscellaneous), Cell biology, General Materials Science, Human specific, Gene, media_common
Abstract

In article number 2001100, Yi‐Chin Toh and co‐workers combine hPSC micropatterning and a temporally‐sequenced induction protocol to specify neuroepithelial (NE) cells in spatial juxtaposition to mesoendoderm cells. This results in the formation of a reproducible and highly‐organized NE tissue. By evaluating NE tissue structural dysmorphia in the micropatterned NE model, gene‐ and drug‐induced neurodevelopmental defects can be successfully modelled. [Image: see text]

Published
2021
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