80 results on '"Semiz, A."'
Search Results
2. Evaluating Antibiofilm, Cytotoxic and Apoptotic Activities of Scutellaria brevibracteata subsp. brevibracteata Essential Oil
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Bozbeyoğlu Kart, Naime Nur, primary, Günal, Batıkan, additional, Mutlu, Doğukan, additional, Mercan Doğan, Nazime, additional, Arslan, Şevki, additional, and Semiz, Gürkan, additional
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- 2023
- Full Text
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3. CD47 (don't eat me signal) expression levels and its relationship with clinicopathologic features in early‐stage prostate carcinoma
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Hüseyin S. Semiz, Ülkü Küçük, Erdem Kısa, Merve Keskinkılıç, Dilara Ecem Süyün, Mehmet Emin Arayıcı, Elif Atağ, and Aziz Karaoglu
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Male ,Oncology ,Urology ,Carcinoma ,Prostate ,Humans ,Prostatic Neoplasms ,CD47 Antigen ,Immunotherapy - Abstract
Background Prostate cancer is a cancer with poor host immune response and could be defined as a non-T-cell inflamed tumor. Therefore, immunotherapy treatments could not be included in the treatment of prostate cancer until recently. Inadequate antitumoral response is one of the main reasons why tumor cells multiply rapidly and cause lethal results. It was shown that CD47 molecule, which is secreted at high levels by leukemia cells, reduces macrophage-mediated phagocytosis and thus facilitates escape from the antitumoral immune response. The aim of this study was to show don't eat me signaling in prostate carcinoma tissues and its relationship with macrophage polarization. Materials and Methods A total of 263 patients with a diagnosis of prostatic adenocarcinoma after radical prostatectomy between 2015 and 2020 at our institute were included in the study. CD47, CD68, and CD163 expression levels were examined immunohistochemically (IHC) in these tissues. The relationship of these expression levels with unfavorable prognostic factors and survival for prostate carcinoma was investigated. Results In this study, all the operated prostate carcinoma cases had CD47 expression in tumor tissue, but only 52.5% had a high level of expression. Of 263 prostate cancer tissues, 135 (51.3%) showed high expression of CD68 protein and 189 (71.9%) showed high expression of CD163 protein. There was a statistically strong relationship between CD47, CD68, and CD163. Conclusions The CD47 molecule is basically a molecule that inhibits macrophage activation. CD68 is mostly used for macrophage classification, while CD163 is used for tumor-associated macrophage classification. Unlike others, we IHC examined CD47, CD68, and CD163 expressions in the surgical materials of patients who were operated for prostate carcinoma. In addition, we concluded that strong CD47 expression was closely associated with strong CD68 and CD163 expression in all tumor samples. However, a significant relationship between these expression levels and survival could not be demonstrated.
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- 2022
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4. Clinical features of generalized lipodystrophy in Turkey: a cohort analysis
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Karabey, Hülya Kayserili (ORCID 0000-0003-0376-499X & YÖK ID 7945); Özışık, Seçil, Simsir, IY; Tuysuz, B; Ozbek, MN; Tanrikulu, S; Guler, MC; Karhan, AN; Ongen, YD; Gunes, N; Soyaltin, UE; Altay, C; Nur, B; Ozalkak, S; Dogan, OA; Dursun, F; Pekkolay, Z; Eren, MA; Usta, Y; Saydam, BO; Adiyaman, SC; Unal, MC; Semiz, GG; Turan, I; Eren, E; Jeru, I; Vigouroux, C; Atik, T; Onay, H; Ozen, S; Oral, EA; Akinci, B, Koç University Hospital, School of Medicine, Karabey, Hülya Kayserili (ORCID 0000-0003-0376-499X & YÖK ID 7945); Özışık, Seçil, Simsir, IY; Tuysuz, B; Ozbek, MN; Tanrikulu, S; Guler, MC; Karhan, AN; Ongen, YD; Gunes, N; Soyaltin, UE; Altay, C; Nur, B; Ozalkak, S; Dogan, OA; Dursun, F; Pekkolay, Z; Eren, MA; Usta, Y; Saydam, BO; Adiyaman, SC; Unal, MC; Semiz, GG; Turan, I; Eren, E; Jeru, I; Vigouroux, C; Atik, T; Onay, H; Ozen, S; Oral, EA; Akinci, B, Koç University Hospital, and School of Medicine
- Abstract
Aim: To describe the Turkish generalized lipodystrophy (GL) cohort with the frequency of each complication and the death rate during the period of the follow-up. Methods: This study reports on 72 patients with GL (47 families) registered at different centres in Turkey that cover all regions of the country. The mean +/- SD follow-up was 86 +/- 78 months. Results: The Kaplan-Meier estimate of the median time to diagnosis of diabetes and/or prediabetes was 16 years. Hyperglycaemia was not controlled in 37 of 45 patients (82.2%) with diabetes. Hypertriglyceridaemia developed in 65 patients (90.3%). The Kaplan-Meier estimate of the median time to diagnosis of hypertriglyceridaemia was 14 years. Hypertriglyceridaemia was severe (>= 500 mg/dl) in 38 patients (52.8%). Seven (9.7%) patients suffered from pancreatitis. The Kaplan-Meier estimate of the median time to diagnosis of hepatic steatosis was 15 years. Liver disease progressed to cirrhosis in nine patients (12.5%). Liver disease was more severe in congenital lipodystrophy type 2 (CGL2). Proteinuric chronic kidney disease (CKD) developed in 32 patients (44.4%) and cardiac disease in 23 patients (31.9%). Kaplan-Meier estimates of the median time to diagnosis of CKD and cardiac disease were 25 and 45 years, respectively. Females appeared to have a more severe metabolic disease, with an earlier onset of metabolic abnormalities. Ten patients died during the follow-up period. Causes of death were end-stage renal disease, sepsis (because of recurrent intestinal perforations, coronavirus disease, diabetic foot infection and following coronary artery bypass graft surgery), myocardial infarction, heart failure because of dilated cardiomyopathy, stroke, liver complications and angiosarcoma. Conclusions: Standard treatment approaches have only a limited impact and do not prevent the development of severe metabolic abnormalities and early onset of organ complications in GL., NA
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- 2023
5. Clinical features of generalized lipodystrophy in Turkey: a cohort analysis
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Yildirim Simsir, Ilgin, primary, Tuysuz, Beyhan, additional, Ozbek, Mehmet Nuri, additional, Tanrikulu, Seher, additional, Celik Guler, Merve, additional, Karhan, Asuman Nur, additional, Denkboy Ongen, Yasemin, additional, Gunes, Nilay, additional, Soyaltin, Utku Erdem, additional, Altay, Canan, additional, Nur, Banu, additional, Ozalkak, Servan, additional, Akgun Dogan, Ozlem, additional, Dursun, Fatma, additional, Pekkolay, Zafer, additional, Eren, Mehmet Ali, additional, Usta, Yusuf, additional, Ozisik, Secil, additional, Ozgen Saydam, Basak, additional, Adiyaman, Suleyman Cem, additional, Unal, Mehmet Cagri, additional, Gungor Semiz, Gokcen, additional, Turan, Ihsan, additional, Eren, Erdal, additional, Kayserili, Hulya, additional, Jeru, Isabelle, additional, Vigouroux, Corinne, additional, Atik, Tahir, additional, Onay, Huseyin, additional, Ozen, Samim, additional, Oral, Elif A., additional, and Akinci, Baris, additional
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- 2023
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6. Author response for 'Clinical features of generalized lipodystrophy in Turkey: a cohort analysis'
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null Ilgin Yildirim Simsir, null Beyhan Tuysuz, null Mehmet Nuri Ozbek, null Seher Tanrikulu, null Merve Celik Guler, null Asuman Nur Karhan, null Yasemin Denkboy Ongen, null Nilay Gunes, null Utku Erdem Soyaltin, null Canan Altay, null Banu Nur, null Servan Ozalkak, null Ozlem Akgun Dogan, null Fatma Dursun, null Zafer Pekkolay, null Mehmet Ali Eren, null Yusuf Usta, null Secil Ozisik, null Basak Ozgen Saydam, null Suleyman Cem Adiyaman, null Mehmet Cagri Unal, null Gokcen Gungor Semiz, null Ihsan Turan, null Erdal Eren, null Hulya Kayserili, null Isabelle Jeru, null Corinne Vigouroux, null Tahir Atik, null Huseyin Onay, null Samim Ozen, null Elif A. Oral, and null Baris Akinci
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- 2023
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7. Review for 'AN ARCHAEOMETRIC STUDY OF THE KONYA BASIN METALLIC WARE THROUGH FT‐IR AND XRD ANALYSIS WITH CHEMOMETRICS: CENTRAL ANATOLIAN EARLY BRONZE AGE CERAMICS'
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Baris semiz
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- 2022
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8. Sudden onset of white fibrous papulosis of the neck and milia cysts on the neck of an elderly female patient
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Ralfi Singer, Özben Yalçın, Ezgi Aktaş Karabay, Yavuz Semiz, and Arzu Dobral
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medicine.medical_specialty ,White (horse) ,business.industry ,Epidermal Cyst ,Dermatology ,Elastic Tissue ,medicine.disease ,Milia ,Female patient ,Humans ,Medicine ,Female ,business ,Neck ,Aged ,Sudden onset - Published
- 2021
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9. CD47 (don't eat me signal) expression levels and its relationship with clinicopathologic features in early‐stage prostate carcinoma
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Semiz, Hüseyin S., primary, Küçük, Ülkü, additional, Kısa, Erdem, additional, Keskinkılıç, Merve, additional, Süyün, Dilara Ecem, additional, Arayıcı, Mehmet Emin, additional, Atağ, Elif, additional, and Karaoglu, Aziz, additional
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- 2022
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10. Morbidly obese pregnant woman with congenital leptin deficiency: Follow‐up and obstetric outcome
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Cagliyan, Erkan, primary, Ozmen, Samican, additional, Timur, Hikmet T., additional, Ozgozen, Mehmet E., additional, and Semiz, Gokcen G., additional
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- 2022
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11. Review for "AN ARCHAEOMETRIC STUDY OF THE KONYA BASIN METALLIC WARE THROUGH FT‐IR AND XRD ANALYSIS WITH CHEMOMETRICS: CENTRAL ANATOLIAN EARLY BRONZE AGE CERAMICS"
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semiz, Baris, primary
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- 2022
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12. Leukocytoclastic vasculitis secondary to COVID‐19 infection presenting with inclusion bodies: A histopathological correlation
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Yavuz Semiz, Özben Yalçın, Esra Yıldırım Bay, Onur Gündoğdu, Elif Moustafa, and İlteriş Oğuz Topal
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medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Leukocytoclastic vasculitis ,Medicine ,Dermatology ,business ,Cutaneous Vasculitis ,Inclusion bodies - Published
- 2021
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13. Body mass index and complications following major gastrointestinal surgery
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Blanco-Colino R, Lee S, Kamarajah SK, Vasko P, Kuiper SZ, Farina V, Chapman SJ, Drake TM, Gavagna L, Pasquali S, Pata F, Pellino G, de la Rosa-Estadella M, Stellingwerf ME, Stijns RCH, Borrellas A, Golding D, Ngaage M, Van Tol RR, de Groof J, de Wilt H, Bemelman WA, McNamee L, Espin-Basany E, Emre Baki B, Gecim IE, Can Tatar O, Bach S, Bhangu A, Bresges K, Burke J, Claireaux HA, Fearnhead N, Fitzgerald JE, Gallagher S, Glasbey JC, Gundogan B, Harrison EM, Hernon J, Khatri C, Kong CY, Lyons A, Mohan M, Morton D, Pinkney TD, Arezzo A, Foppa C, Morino M, Rubbini M, Selvaggi F, Sensi B, Sica G, Orhalmi J, Naccari P, Sgrò A, Burger BHCM, Fares DA, Spijkerman R, van Elst TR, Wiersema R, Stassen LPS, Rodriguez Garcia R, Özkan BB, Tavuz AI, Demirci ZS, Baki BE, Choi PJ, O'Sullivan H, Salman M, Simioni A, Colombo F, Turati L, Cazzola FE, Gallo G, Perrotta G, Papandrea M, Naccari PM, Menduni N, Rossi E, Chetta N, Romeo F, Giordano F, Randisi B, Curletti G, Kuiper J, Costa A, Marcos Rodrigo A, Sanchez A, Varo Muñoz A, Martinez Rios CE, Aliseda-Jover D, Fernandez Nieto D, Alvarez Reyes I, Dominguez Rodriguez LM, Hernandez Ros MI, Esteban Sinovas O, Bartrina Soler P, Villarejo Campos P, Laguna Román S, Fontanet-Soler S, Raurich-Leandro J, Dominguez-Prieto V, Segura-Sampedro JJ, Alconchel-Gago F, Salazar-García C, Gezen AE, Sahin A, Atasoy H, Yuksek B, Arslan E, Ozmen BB, Sen AY, Erol HI, Ucar E, Aktas MK, Yurdaor SS, Mermer S, Seyhan U, Tosun V, Gunaydin Y, Ekinci ZB, Yazkan Z, Choi J, Yeoh TSL, Jones CS, Venturini S, Saat MI, Loo J, Pike G, Davies SC, Kabariti R, Olivier J, Hurný M, Žebrák R, Machačová A, Schulzová M, Smolák P, Široká M, Palyzová H, Jaroš J, Dušek T, Šimáčková B, Bartoš M, Sotona O, Pös M, Karásek D, Higgins P, Hacking S, Arora E, Coughlan G, Palanivail N, Quill S, Zhang AA, Malak M, Maan DS, Cheema J, Goh AWJ, Shamsul Badrin AK, Guinness F, Howard James N, Neary A, Sebaoui S, Gilroy D, Petrov G, Craven K, MacDonald A, Redmond A, Brennan D, Roche D, O'Dwyer M, Collins P, Edwards S, Doyle J, Tiedt L, Arthurs B, O'Byrne L, Kiely A, Glynn M, Sproule L, Heaney A, Li Hi Shing S, Goh W, Al-Nasser Z, Al-Nasser A, Teh JW, De Boni D, Goldin E, Ciccioli E, Vendramin E, Marchese N, Bruno M, Vinci A, Harder G, Morandi V, Magnoli M, Suppa A, Palmieri A, Martorana M, Sette M, Balagna P, Cruciani C, Corte M, Ciano P, Bagaglini G, Montuori M, Di Benedetto L, Arcudi C, Pezzuto R, Saraceno F, Milana F, Franceschilli M, Rizzi A, Sampietro G, Rampulla V, Bianco F, Boschetti ME, Ghignone F, Bianchini S, Esposto R, Riva L, Riva M, Cannavò M, Arrigo A, Giavarini L, Colombo EM, Trompetto M, Clerico G, Catalano M, Dosa T, El Mabruk M, Barone V, Pallara E, Pasqualoni M, Caudullo G, Mastandrea Bonaviri GN, Muro M, Pistola I, Verardi L, Ferrara D, Gerardi S, Remore LM, Belia F, Del Coco F, Larotonda C, Botrugno EM, Cammarota A, Di Girolami L, Laterza V, Laurino A, Paolo G, Santocchi P, Puccioni C, Truma A, Giardino FR, Giuffrida A, Ripa M, Cautiero R, Patturelli M, Capozzolo A, Selvaggi L, Facchiano A, Milazzo LF, Papazachariou SK, Pattapola V, Anania G, Feo C, Bellinato M, Priani P, Zigiotto D, Troia A, Vable T, Piran G, Targa S, Pulpito S, Tagariello F, Fasano A, Anconelli D, Castiglione F, Tognolo L, Lopez G, Campion A, Tarantino M, Sacco R, Sammarco G, Palmisano S, Giacca M, Rocco I, Bellio G, Favero A, Raimondi P, Pantalone MR, De Nardi P, Notarnicola M, Picciariello A, Licari L, Parinisi Z, Fazzotta S, Ciciliot M, Reggiani L, Mariani F, Aonzo P, Checcacci P, Montanelli P, Guerra F, Skalamera I, Staderini F, Grandi S, Nelli T, de Boer DV, van der Pool AEM, Janssen TL, El-Atmani S, van Verschuer VMT, Poelman M, Dronkers WJ, van Steensel L, Toorenvliet BR, Duinhouwer LE, Vermaas M, Ter Bruggen FFJA, Hogendoorn W, van der Harst E, van Rijckevorsel VAJIM, Bayoumy AB, Lap CR, Gooszen JAH, Abdulrahman N, de Roy van Zuidewijn D, de Groof EJ, Zijlmans JL, van Dalen ASHM, Bos K, Musters GD, Looijen RC, Fliers JM, Oostendorp SE, Mosterd CM, Blonk L, Jurgens J, Ribbink ME, Boom MS, Boersma AM, Hidding E, Schmidt PA, Mensink G, Graus SA, Gastel MDA, Veenker CGH, Van Heumen TM, Slieker FJB, Sedee WJA, Löwensteyn YN, Amelung FJ, de Guerre LEVM, Nota CLMA, Van Dijck WPM, van Wijnbergen JWM, Pronk A, Kip M, van der Zee C, Heiloo S, Muller S, Verboeket B, Oudman TS, Zope S, Gilissen V, Gommers J, Cremers D, Van der Lubbe M, Smet M, Ter Weele K, de Bruin M, Geerlings M, Ter Horst L, Kerimova N, Pesser N, Heesakkers H, de Mees T, de Gooyer JM, Willems L, Gawria L, Bonouvrie D, Harms J, Eggen Y, Hengeveld E, Smeets HJ, Hoffman RPC, Detmers Blom FPN, Van Bruggen D, Steup WH, Gooiker GA, Willems YR, van der Hoeven AC, Vallve-Bernal M, Perez-Gandara B, Perez JL, Caballero Rodriguez E, Perez Febles M, Protti Ruiz GP, Hidalgo Pujol M, Alberti Delgado P, Gil Barrionuevo E, Anabitarte O, Caballero L, Poyato Nuñez FJ, Prado Perez R, de la Portilla de Juan F, Fulgencio Barbarin J, Elorza Echaniz G, Mitxelena Elosegi L, Delgado AT, Marti Gelonch L, Gonzalez Arribas M, De Serra Tejada I, Alberdi San Roman I, de Andres Olabarria U, Fernández-Domper L, Perez Costoya C, Perez Arias H, Fa Binefa M, Becerra Nieves M, Escalona Canal MG, Aldrey I, Vazquez-Gonzalez I, Falcon Cazas A, Amarelo Garcia M, Gonzalez Ruiz AA, Garcia Garrido M, Simon Frapolli V, Martinez Diaz JM, De la Torre Conde C, Rodrigues Silva K, Hernandez Kakauridze S, Lopez Garcia MC, Flores Funes D, Gómez-López de San Román C, San Martín Bragado M, Tejero Pintor FJ, Pando Ruiz B, Sánchez Estébanez E, Roquet Puigneró E, Pla Seró S, Vela Polanco FF, Mirallas Viñas O, Caro Gonzalez MP, Bertelli Puche JL, Gonzalez-Martinez A, Sanchez Cambronero M, Garcia Torres A, Dominguez Jimenez M, de Jesus Rodriguez Perdomo M, Echazarreta-Gallego E, Sánchez-Blasco L, Del Mar López-Cuevas M, Latras-Cortés I, López-Vendrell L, Díaz Padillo A, Mestres Petit N, Cruz Reyes JA, Fernandez C, Posada M, Moratilla Lapeña L, Martin Morales E, Mate-Mate P, Garcia Cruz G, Gorini L, Rubio-Perez I, Soldevila-Verdeguer C, Jiménez-Viñas C, Luehrman A, Sena-Ruiz F, Garcia-Perez JM, Plomer-Sanchez M, Pujol-Cano N, Jimenez-Segovia M, Diaz-Jover P, Pineño-Flores C, Ambrona-Zafra D, Gonzalez-Argente XF, Jiménez-Morillas P, López-Mármol R, Durán-Martínez M, González-Crespo A, Checa Guillen M, Valderrama Pérez A, Claramonte Bellmunt O, Martí Fernández RM, Kasap S, Soylemez ZOBB, Bolat AB, Aydar SEYI, Birgin BZ, Coskun O, Cakir SG, Belibagli ZO, Herken M, Erdem S, Kayacan S, Kelesoglu Y, Moran D, Atalay H, Kucukdiler E, Demirci A, Buyukkasap C, Kuzey A, Emral C, Dogan H, Cok H, Durmaz H, Asma A, Ergul B, Kaya A, Bilicen G, Gunay M, Senturk E, Baskoy L, Besısık HM, Topalan K, Piraliyev E, Danalıoglu AN, Ilbak A, Yıgman S, Kara C, Guzel M, Inci ET, Onsal U, Erel T, Cetin SK, Yekenkurul E, Kasar P, Saglam ZA, Gursoy F, Cetinkaya M, Aktekin H, Bober DN, Mugurtay YS, Koksal G, Celik S, Bektur G, Yildirim R, Ankarali T, Güven H, Yuksel A, Semiz A, Cise S, Tomas K, Ulusahin M, Akbulut F, Tulum H, Bodur S, Isler VC, Pektas AM, Mutlu D, Mericliler M, Tansoker I, Polat ZP, Seyrek N, Beyatli S, Toto OF, Cakaloglu HC, Sapci I, Akpunarli B, Adiyaman C, Kobal BB, Gok Z, Benli S, Turpan M, Kocapinar S, Parimli H, Acar S, Eger M, Yilmaz I, Cengiz U, Yoruk I, Mutlu B, Ulkucu A, Arukan C, Kara B, Gokce K, Calisgan B, Demirci K, Elkatroushi T, Ayaz B, Uzun B, Sivrikaya T, Goksoy B, Eroz E, Celik B, Canbay Torun B, Ekin B, Senay BB, Temiz C, Yilmaz M, Yasar C, Cakir E, Subasi A, Celik K, Aksoy K, Karabulut E, Altintas O, Bali AN, Ciftci E, Babaoglu H, Aljbour A, Aljbour I, Akcaoglu T, Kakil E, Taskin O, Taskin RB, Topal U, Huzmeli E, Caliskan T, Unal AG, Yurekli AM, Sari V, Tutam DN, Celen D, Posteki G, Demirtas B, Yildiz S, Kilic E, Yalcin Y, Kurt A, Gozubuyuk Y, Huseynova S, Cinar S, Calar SN, Kurklu O, Binbuga M, Ceylan C, Yavuz G, Alim YE, Yildirim N, Yilmaz S, Onar D, Aray E, Ozsipahi AC, Koc GE, Yetiskin E, Kocer MD, Ozgencil B, Bahcecioglu B, Hacioglu AD, Bilici O, Cin S, Uzunoglu EC, Cumen EC, Aslan L, Erozgur B, Yildiz SS, Zengin T, Kullac S, Mizan SR, Baykan B, Kopac O, Karabacak U, Aytekin A, Deliktas TS, Buyukkarabacak Y, Uzun O, Karahan B, Turkmen M, Akdogan A, Uctepe F, Bandirmali O, Erdogan P, Demir F, Bozkurt GK, Yilmaz T, Sheikh IMI, Orhan K, Balci B, Keyif MF, Bilgin S, Cantimer E, Yaman S, Akkaya E, Atesavci SN, Arslan U, Asik M, Koksal S, Murtaza MI, Mustafa S, Oun H, Sam ZH, Brogan A, Zaidi R, Quinn K, Taylor F, Pang G, Heath H, Smart NJ, Home J, Mauro D, Noone TM, Fenn J, Sinha A, Lowe R, Hutchings I, Longstaff L, Smith AG, Edwards JA, Alcocer BP, Oakley T, Thomas-Davies M, Hourston GJM, Kankam HKN, Ramana A, Baker C, Endo Y, Wong C, Anderson RGJ, Badran A, Ali A, Myers L, Tippins F, Stanley S, Sandison L, Schofield E, Delf J, Rees S, Anyan-Brown J, Long K, Archer M, Anakwenze V, Goel S, Sharma Khatiwada A, Khan S, Leafe O, Lee J, Embury-Young Y, Edwards L, Hazenberg P, Agrawal M, Guerero D, Britton F, Rejayee M, Mahesh S, Khaing PH, Baldwin A, Iyer S, Gaskell P, Adlan A, Cuckow L, Barmayehvar B, Rob T, Ciurleo C, Mural-Krishnan S, Jong N, Carlson S, Abdelgalil R, Goble M, Doshi A, Ogunleye O, Marsh L, Bagley J, Poacher A, Cantelo J, Wylie J, Govil S, Hill F, Beaver D, Urquhart A, Rakhimov I, Raina V, Clifford T, Iorga R, Cartwright E, Harris AJ, Shurovi B, Wadanamby S, Brown E, Bradley C, Ahmad A, Jeyabraba S, Hardaman B, Truss A, Mohamed US, Örhalmi J, Kerin MJ, Reynolds J, Ridgway P, Pietrabissa A, Foschi D, Sgroi G, Rosati G, Benevento A, Coco C, Persiani R, Vasquez G, Messina F, De Manzini N, Innocenti P, Rosati R, Altomare DF, Sartori A, Salamone G, Galleano R, Cianchi F, Wijnhoven BPL, van de Ven AWH, de Vos Tot Nederveen Cappel RJ, de Castro SMM, Meijerink WJHJ, Mulder IM, Acherman YIZ, van Leeuwen BL, Schasfoort RA, Kloppenberg FWH, Wiezer R, Consten ECJ, Van Grevenstein WMU, Schiphorst A, Wijffels N, Uittenbogaart M, Klinkert M, Koppe M, de Hingh I, Konsten J, Polat F, Berends F, Langenhoff B, Zimmerman D, van Engelenburg T, Vries JJM, Baeten CIM, Bastiaansen AJNM, van Geloven A, Khan I, Girones J, Barrera Gomez M, Sanz Ortega G, Duran Muñoz-Cruzado VM, Ruiz Montesinos I, Enriquez-Navascues JM, Portugal Porras V, Baixauli J, Garcia Florez LJ, Alonso Gonçalves S, Parajo A, Sanchez-Guillen L, Lujan Mompean JA, Soria Aledo V, Arenal JJ, Blanco Antona F, Badia JM, Roura J, Garcia Garcia J, Elía-Guedea M, Millan M, Viñas-Salas J, Garcia-Olmo D, Prieto-Nieto MI, Medina-Fernández FJ, Romero-Simó M, Frasson M, Espí Macías A, Tirnaksiz MB, Leventoglu S, Kara E, Taşçı Y, Pehlivan M, Guner A, Ozben V, Agalar C, Albayrak D, Ertekin C, Oncel M, Sakman G, Guler SA, Firat O, Akkucuk S, Ozbalci GS, Sozuer EM, Sengul N, Schizas A, Horgan PG, Singh B, Harikrishnan A, Stechman M, Hayat J, Coyne P, Wilson T, Arun C, Manvydas V, Moroni P, Lo Secco G, Argenti F, Romano F, Calcagno P, Steccanella F, Cisternino G, Bottini C, Realis Luc A, Apicella M, Candilio G, Gubbiotti F, De Luca E, Casagranda B, Decorato A, Aquilino F, Badii B, Rahmee CNS, Kleine E, Yauw S, de Zeeuw S, Aarts E, Teixeira da Silva M, Brueren L, Bokkerink G, Schok T, Graafland M, Gonzalez de Chaves PE, Jimenez-Gomez LM, García Galocha JL, Palos Campos MC, Jimenez Escovar F, Hernandez-Lizoáin JL, Monzonis Hernandez X, Dominguez Sanchez JM, Vives-Rodriguez E, Abrisqueta Carrion J, Beltrán de Heredia J, Padilla Valverde D, Alcazar Montero JA, Córdoba-Díaz de Laspra E, Franco Chacón M, Muriel P, Pastor-Riquelme P, Peinado Iribar B, Alonso Hernandez N, Costa-Navarro D, Martínez Chillarón E, Secilmis E, Bamac E, Koç F, Kayaci Durak M, Bayram S, Ekrem M, Uzun S, Gok AFK, Gorguner F, Yildiz T, Dalci K, Kilinc C, Koç M, Yuksek MA, Ersoy T, Celik E, Parmar E, Abuhussein N, Metcalf P, Atif M, Heywood E, Mayes JW, Kelly M, Mitchell H, Antoniou I, Dean R, Davies N, Trecarten S, Henderson I, Holmes C, Shuttleworth RH, Jindal A, Hughes F, Gouda P, Fleck R, Hanrahan M, Karunakaran P, Chen JH, Sykes MC, Sethi RK, Suresh S, Patel P, Patel M, 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JA, McLure SW, Pal S, Rangedara A, Baker AN, Asbjoernsen CA, Girling C, Gray L, Gauntlett L, Joyner C, Qureshi S, Mogan YP, Ng JCK, Kumar AN, Park JH, Tan D, Choo KP, Raman KP, Buakuma P, Xiao C, Govinden S, Thompson OD, Charalambos MA, Karsan RB, Dogra T, Bullman LM, Dawson PM, Frank AL, Abid H, Tung L, Qureshi U, Tahmina A, Matthews BW, Harris RT, O'Connor A, Mazan K, Iqbal S, Stanger SA, Thompson JD, Sullivan JAL, Uppal E, MacAskill A, Bamgbose FA, Neophytou C, Carroll AF, Rookes CW, Datta U, Dhutia AJ, Rashid S, Ahmed N, Lo T, Bhanderi S, Blore CD, Ahmed S, Shaheen H, Abburu S, Majid S, Abbas Z, Talukdar SS, Burney LJ, Patel JB, Al-Obaedi O, Roberts AW, Mahboob S, Sheth S, Karia P, Prabhudesai A, Kow K, Koysombat K, Wang S, Morrison P, Maheswaran Y, Keane P, Copley PC, Brewster O, Xu GX, Harries P, Wall C, Al-Mousawi A, Bonsu S, Cunha P, Ward T, Paul J, Nadanakumaran K, Tayeh S, Holyoak H, Remedios J, Theodoropoulou K, Luhishi A, Jacob L, Long F, Atayi A, Sarwar S, Parker O, Harvey J, Ross H, Rampal R, Thomas G, Vanmali P, McGowan C, Stein J, Robertson V, Carthew L, Teng V, Fong J, Street AN, Thakker CE, O'Reilly D, Bravo M, Pizzolato A, Khokhar HA, Ryan M, Cheskes L, Carr R, Salih AE, Bassiony S, Yuen R, Chrastek D, Rosen O'Sullivan H, Amajuoyi A, Wang A, Sitta O, Wye J, Qamar MA, Major C, Kaushal A, Morgan C, Petrarca M, Allot R, Verma K, Dutt S, Chilima CP, Peroos S, Kosasih SR, Chin H, Ashken L, Pearse RJ, O'Loughlin RA, Menon A, Singh K, Norton J, Sagar R, Jathanna N, Rothwell L, Watson N, Harding F, Dube P, Khalid H, Punjabi N, Sagmeister M, Gill P, Shahid S, Hudson-Phillips S, George D, Ashwood J, Lewis T, Dhar M, Sangal P, Rhema IA, Kotecha D, Afzal Z, Syeed JA, Prakash E, Jalota P, Herron J, Kimani L, Delport A, Shukla A, Agarwal V, Parthiban S, Thakur H, Cymes W, Rinkoff S, Turnbull JA, Hayat M, Darr S, Khan U, Lim J, Higgins A, Lakshmipathy G, Forte B, Canning E, Jaitley A, Lamont J, Toner E, Ghaffar A, McDowell M, Salmon D, O'Carroll O, Khan A, Kelly ME, Clesham K, Palmer C, Lyons R, Bell A, Chin R, Waldron RM, Trimble A, Cox SE, Ashfaq U, Campbell J, Holliday RBS, McCabe G, Morris F, Priestland R, Vernon OK, Ledsam A, Vaughan R, Lim D, Bakewell ZR, Hughes RK, Koshy RM, Jackson HR, Narayan P, Cardwell AE, Jubainville CL, Arif T, Elliott LE, Gupta V, Bhaskaran G, Odeleye A, Ahmed F, Shah R, Pickard J, Suleman YN, North AS, McClymont LF, Hussain N, Ibrahim I, Ng GS, Wong V, Lim AE, Harris LN, Tharmachandirar T, Mittapalli D, Patel V, Lakhani M, Bazeer HZ, Narwani V, Sandhu KK, Wingfield LR, Gentry S, Adjei H, Bhatti M, Braganza L, Barnes J, Mistry S, Chillarge G, Stokes S, Cleere J, Bucko AM, Meek J, Boxall N, Heywood EG, Wiltshire JJ, Toh C, Ward AE, Shurovi BN, Horth D, Patel BY, Ali B, Spencer T, Axelson T, Kretzmer L, Chhina C, Anandarajah C, Fautz T, Horst C, Thevathasan AA, Ng JQ, Hirst F, Brewer CF, Logan AE, Lockey JW, Forrest PR, Keelty N, Wood AD, Springford LR, Avery P, Schulz TM, Bemand TP, Howells L, Collier H, Khajuria A, Tharakan RG, Parsons S, Buchan AM, McGalliard RJ, Mason JD, Cundy OJ, Li N, Redgrave NA, Watson RP, Pezas TP, Dennis YF, Segall E, Hameed M, Lynch AS, Chamberlain M, Peck FS, Neo YN, Russell G, Elseedawy M, Foster NL, Soo YH, Puan L, Dennis R, Goradia H, Qureshi A, Osman S, Reeves T, Dinsmore L, Marsden M, Lu Q, Pitts-Tucker T, Dunn CE, Walford RA, Heathcote E, Martin R, Pericleous A, Brzyska K, Reid KG, Williams MR, Wetherall N, McAleer E, Thomas D, Kiff R, Milne S, Holmes MJV, Bartlett J, Lucas de Carvalho J, Bloomfield T, Tongo F, Bremner RH, Yong N, Atraszkiewicz BA, Mehdi A, Tahir M, Sherliker GXJ, Tear AK, Pandey A, Broyd A, Omer HM, Raphael M, Chaudhry WW, Shahidi S, Jawad AS, Gill CK, Hindle Fisher I, Adeleja I, Clark IJ, Aidoo-Micah GE, Stather PW, Salam GJ, Glover TE, Deas G, Sim NK, Obute RD, Wynell-Mayow WM, Sait MS, Mitha N, de Bernier GL, Siddiqui M, Shaunak R, Wali A, Cuthbert G, Bhudia R, Webb E, Shah S, Ansari N, Perera M, Kelly N, McAllister R, Stanley GH, Keane CP, Shatkar V, Maxwell-Armstrong C, Henderson LA, Maple N, Manson R, Adams RD, Semple E, Mills M, Daoub A, Marsh A, Ramnarine A, Hartley J, Malaj M, Jewell PD, Whatling EA, Hitchen N, Chen M, Goh B, Fern J, Rogers S, Derbyshire L, Robertson DT, Deekonda P, Abid A, Harrison PLM, Aildasani L, Turley H, Sherif MA, Pandey G, Filby JJ, Johnston A, Burke E, Mohamud M, Gohil K, Tsui AY, Singh R, Lim SJ, O'Sullivan K, McKelvey LL, O'Neill S, Roberts HF, Brown FS, Cao Y, Buckle RT, Liew Y, Sii S, Ventre CM, Graham CJ, Filipescu T, Yousif A, Dawar R, Wright A, Peters M, Varley R, Owczarek S, Hartley S, Khattak M, Iqbal A, Ali M, Durrani B, Narang Y, Bethell GS, Horne L, Pinto R, Nicholls K, Kisyov I, Torrance HD, English W, Lakhani SM, Ashraf SF, Venn M, Elangovan V, Kazmi Z, Brecher J, Sukumar S, Mastan A, Mortimer A, Parker J, Boyle J, Elkawafi M, Beckett J, Mohite A, Narain A, Mazumdar E, Sreh A, Hague A, Weinberg D, Fletcher L, Steel M, Shufflebotham H, Masood M, Sinha Y, Jenvey C, Kitt H, Slade R, Craig AR, Deall C, Reakes T, Chervenkoff J, Strange E, O'Bryan M, Murkin C, Joshi D, Bergara T, Naqib S, Wylam D, Scotcher SE, Hewitt CM, Stoddart MT, Kerai A, Trist AJ, Cole SJ, Knight CL, Stevens S, Cooper GE, Ingham R, Dobson J, O'Kane A, Moradzadeh J, Duffy A, Henderson C, Ashraf S, McLaughin C, Hoskins TC, Reehal RS, Bookless LR, McLean RC, Stone EJ, Wright EV, Abdikadir HR, Roberts C, Spence O, Srikantharajah M, Ruiz EM, Matthews JH, Gardner E, Hester E, Naran P, Simpson R, Minhas M, Cornish E, Semnani SA, Rojoa D, Radotra A, Eraifej J, Eparh K, Smith DNE, Mistry BD, Hickling SL, Din W, Liu C, Mithrakumar P, Mirdavoudi V, Rashid M, Mcgenity C, Hussain O, Kadicheeni M, Gardner H, Anim-Addo N, Pearce J, Aslanyan A, Ntala C, Sorah T, Parkin J, Alizadeh M, White A, Edozie F, Johnston J, Kahar A, Navayogaarajah V, Carter D, Khonsari P, Burgess A, Patel B, Kong C, Ponweera A, Cody A, Tan Y, Ng AYL, Croall A, Allan C, Ng S, Raghuvir V, Telfer R, Greenhalgh AD, McKerr CN, Edison MA, Patel BA, Dear K, Hardy MR, Williams P, Hassan S, Sajjad U, O'Neill EM, Lopes S, Healy L, Jamal N, Tan S, Lazenby D, Husnoo SB, Beecroft S, Sarvanandan T, Weston C, Bassam N, Rabinthiran S, Hayat U, Ng L, Varma D, Sukkari M, Mian A, Omar A, Kim JW, Sellathurai J, Mahmood J, O'Connell C, Bose R, Heneghan H, Lalor P, Matheson J, Doherty C, Cullen C, Cooper D, Angelov S, Drislane C, Smith ACD, Kreibich A, Palkhi E, Durr A, Lotfallah A, Gold D, Mckean E, Dhanji A, Anilkumar A, Thacoor A, Siddiqui ZH, Lim S, Piquet A, Anderson SM, McCormack DR, Gulati J, Ibrahim A, Murray SE, Walsh SL, McGrath A, Ziprin P, Chua EY, Lou CN, Bloomer J, Paine HR, Osei-Kuffour D, White CJ, Szczap A, Gokani S, Patel K, Malys MK, Reed A, Torlot GE, Cumber EM, Charania A, Ahmad S, Varma N, Cheema H, Austreng L, Petra H, Chaudhary M, Zegeye MI, Cheung F, Coffey D, Heer RS, Singh S, Seager E, Cumming S, Suresh RS, Verma S, Ptacek IB, Gwozdz AM, Yang T, Khetarpal AA, Shumon S, Fung TMP, Leung W, Kwang P, Chew L, Loke W, Curran A, Chan C, McGarrigle C, Mohan K, Cullen S, Wong E, Toale C, Collins D, Keane N, Traynor BP, Shanahan D, Yan A, Jafree DJ, Topham C, Mitrasinovic S, Omara S, Bingham G, Lykoudis PM, Miranda BH, Whitehurst K, Kumaran G, Devabalan Y, Aziz H, Shoa M, Dindyal S, Yates JA, Bernstein I, Rattan G, Coulson R, Stezaker S, Isaac A, Salem M, McBride A, McFarlane H, Yow L, MacDonald J, Bartlett RD, Turaga S, White U, Liew W, Yim N, Ang A, Simpson A, McAuley D, Craig E, Murphy L, Shepherd P, Kee JY, Abdulmajid A, Chung A, Warwick HL, Livesey A, Holton P, Theodoreson MD, Jenkin SL, Turner J, Entwisle JH, Marchal ST, O'Connor S, Blege HK, Aithie JM, Sabine LM, Stewart GE, Jackson S, Kishore A, Lankage CM, Acquaah F, Joyce HL, McKevitt KL, Coffey CJ, Fawaz AS, Dolbec KS, O'Sullivan DA, Geraghty JM, Lim E, Bolton L, FitzPatrick D, Robinson C, Ramtoola T, Collinson S, Grundy L, McEnhill PM, Harbhajan Singh GS, Loughran D, Golding DM, Keeling RE, Williams RP, Whitham RDJ, Yoganathan S, Nachiappan R, Egan RJ, Owasil R, Kwan ML, He A, Goh RW, Bhome R, Wilson H, Teoh PJ, Raji K, Jayakody N, Matthams J, Chong J, Luk CY, Greig RJ, Trail M, Charalambous G, Rocke AS, Gardiner N, Bulley F, Warren N, Brennan E, Fergurson P, Wilson R, Whittingham H, Brown EJ, Khanijau R, Gandhi K, Morris S, Boulton AJ, Chandan N, Barthorpe AE, Maamari R, Sandhu S, McCann M, Higgs L, Balian V, Reeder C, Diaper C, Sale T, Ali H, Archer CH, Clarke AK, Heskin J, Hurst PC, Farmer JD, O'Flynn LD, Doan L, Shuker BA, Stott GD, Vithanage NA, Hoban KA, Nesargikar PN, Kennedy HR, Grossart CM, Tan ESM, Roy CSD, Sim P, Leslie KE, Sim D, Abul MH, Cody N, Tay AY, Woon E, Sng S, Mah J, Robson J, Shakweh E, Wing VC, Mills H, Li MM, Barrow TR, Balaji S, Jordan HEM, Phillips C, Naveed H, Hirani S, Tai A, Ratnakumaran R, Sahathevan A, Shafi AMA, Seedat M, Weaver R, Batho A, Punj R, Selvachandran H, Bhatt N, Botchey S, Khonat Z, Brennan K, Morrison CJ, Devlin E, Linton A, Galloway E, McGarvie S, Ramsay N, McRobbie HD, Whewell H, Dean W, Nelaj S, Eragat M, Mishra A, Kane T, Zuhair M, Wells M, Wilkinson D, Woodcock N, Sun E, Aziz N, Abd Ghaffar MK., Nepogodiev, Dmitri, Rosati, Riccardo, Nepogodiev, D., and Robotics and image-guided minimally-invasive surgery (ROBOTICS)
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Male ,obesity ,Multivariate analysis ,Gastrointestinal Diseases ,IMPACT ,Settore MED/18 - CHIRURGIA GENERALE ,Body mass index ,Body weight ,Digestive tract ,Gastrointestinal tract ,Obesity ,Postoperative complications ,Gastroenterology ,digestive tract ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,0302 clinical medicine ,Risk Factors ,Medicine ,Prospective Studies ,Prospective cohort study ,Aged ,Europe ,Female ,Gastrointestinal Neoplasms ,Humans ,Middle Aged ,Postoperative Complications ,Body Mass Index ,OUTCOMES ,body mass index ,body weight ,gastrointestinal tract ,030220 oncology & carcinogenesis ,Meta-analysis ,Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] ,Cohort ,030211 gastroenterology & hepatology ,Cohort study ,medicine.medical_specialty ,Malignancy ,NO ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,business.industry ,postoperative complications ,MORTALITY ,medicine.disease ,Settore MED/18 ,Surgery ,Postoperative complication ,Postoperative Complications, Obesity, Digestive Tract, Gastrointestinal Tract, Body Mass Index, Body Weight ,business - Abstract
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results.Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery for malignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49-2.96, P Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease.
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- 2018
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14. Development of lentigo maligna in a patient with facial mycosis fungoides: A rare association
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Semiz, Yavuz, primary, Aktaş, Ezgi, additional, Şengör Aygün, Mine İlayda, additional, and Yalçın, Özben, additional
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- 2022
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15. Case of chilblain lupus triggered by adalimumab therapy in a patient with psoriasis
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Semiz, Yavuz, primary, Yıldırım Bay, Esra, additional, Oğuz Topal, İlteriş, additional, and Yalçın, Özben, additional
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- 2021
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16. Leukocytoclastic vasculitis secondary to COVID‐19 infection presenting with inclusion bodies: A histopathological correlation
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Yıldırım Bay, Esra, primary, Moustafa, Elif, additional, Semiz, Yavuz, additional, Gündoğdu, Onur, additional, Oguz Topal, Ilteris, additional, and Yalçın, Özben, additional
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- 2021
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17. Development of lentigo maligna in a patient with facial mycosis fungoides: A rare association
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Yavuz Semiz, Ezgi Aktaş, Mine İlayda Şengör Aygün, and Özben Yalçın
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Hutchinson's Melanotic Freckle ,Lentigo ,Mycosis Fungoides ,Skin Neoplasms ,Face ,Humans ,Dermatology ,Facial Neoplasms - Published
- 2022
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18. Does Gadoterate Meglumine Cause Gadolinium Retention in the Brain of Children? A Case–Control Study
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Yasar Bukte, Elif Dilara Topcuoglu, Aslıhan Semiz Oysu, and Osman Melih Topcuoglu
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Gadolinium DTPA ,Adolescent ,Gadolinium ,Population ,Contrast Media ,chemistry.chemical_element ,Meglumine ,Cerebrospinal fluid ,Organometallic Compounds ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Child ,education ,Retrospective Studies ,education.field_of_study ,business.industry ,Significant difference ,Case-control study ,Brain ,Magnetic Resonance Imaging ,Pons ,Cerebellar Nuclei ,chemistry ,Case-Control Studies ,Child, Preschool ,business ,Nuclear medicine ,Pediatric population ,GADOTERATE MEGLUMINE - Abstract
BACKGROUND Accumulation of macrocyclic gadolinium agents in children's brains remain to be determined. PURPOSE To demonstrate whether there is an intracranial macrocyclic gadolinium deposition after multiple contrast-enhanced MRI with gadoterate meglumine in a pediatric population. STUDY TYPE Retrospective case-control. POPULATION In all, 45 children (age range: 5-17 years; mean, 13.7 ± 3.4 years) for the study group and 45 healthy children (age range: 5-17 years; mean, 13.7 ± 3.4 years) for the control group. FIELD STRENGTH/SEQUENCE T1 - and T2 -weighted axial images on a 1.5T scanner. ASSESSMENT Children with at least three enhanced brain MRIs and an age- and sex-matched control group with an unenhanced brain MRIs were compared in terms of T1 signal intensity (SI). All patients in the study group received gadoterate meglumine intravenously (0.1 mmol/kg). SI measurements were made by drawing six regions of interest (ROIs): dentate nuclei (DN), pons, globus pallidi (GP), frontal white matter (FWM), thalamus (T), clivus, and cerebrospinal fluid (CSF) for both groups on unenhanced T1 -weighted images. STATISTICAL TESTS Student's t-test was used for comparison of SI. The Pearson correlation was calculated for the correlation between the SI and the number of gadolinium administrations. RESULTS A significant difference was detected between two groups for DN/CSF, pons/CSF, GP/CSF, thalamus/CSF, and FWM/CSF (P
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- 2019
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19. Case of chilblain lupus triggered by adalimumab therapy in a patient with psoriasis
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Yavuz Semiz, Esra Yıldırım Bay, İlteriş Oğuz Topal, and Özben Yalçın
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Dermatology - Published
- 2021
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20. High performance chromium (VI) removal from water by polyacrylonitrile-co-poly (2-ethyl hexylacrylate) and polyaniline nanoporous membranes
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Usanmaz, Ali, Bozkır, Selçuk, Semiz, Levent, Sankır, Mehmet, Demirci Sankır, Nurdan, Usanmaz, Ali, Bozkır, Selçuk, Semiz, Levent, Sankır, Mehmet, and Demirci Sankır, Nurdan
- Abstract
This article reports the chromium (VI) removal from water by preparing polyacrylonitrile-co-poly (2-ethyl hexylacrylate) (PAN(92)-co-P2EHA(8)) and polyaniline (PANI) nanoporous membranes at various PANI loadings. It was observed that chromium (VI) rejections of nanoporous membranes are highly concentration and pH dependent. Almost complete chromium removal (99.9%) with higher flux values (120-177 L m-2 h-1) was observed for nanoporous membranes. Moreover, nanoporous membranes were also demonstrated as fouling resistant. Total flux loss was low and a part was attributed to reversible flux loss, which cannot cause any permanent hysteresis and easily overcome with simple washing. Scanning electron microscopy (SEM) studies were performed for identifying cross sectional morphology. It was pointed out that pore size should be small enough for filtration and optimized for higher flux but pores should be functionalized for rejection. Chemical structure, swelling ratios, sheet resistivity, and fracture morphologies of nanoporous membranes were reported. POLYM. ENG. SCI., 2012. (C) 2012 Society of Plastics Engineers, Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [108T099], Contract grant sponsor: The Scientific and Technological Research Council of Turkey; contract grant number: 108T099.
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- 2021
21. Sudden onset of white fibrous papulosis of the neck and milia cysts on the neck of an elderly female patient
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Aktaş Karabay, Ezgi, primary, Semiz, Yavuz, additional, Singer, Ralfi, additional, Dobral, Arzu, additional, and Yalçın, Özben, additional
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- 2021
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22. Safety of hospital discharge before return of bowel function after elective colorectal surgery
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J Chapman, S, Blanco-Colino, R, Pérez-Ajates, S, O Anabitarte Bautista, Hodson, J, C Glasbey, J, Pata, F, Pellino, G, Sgrò, A, Soares, A, T van Elst, S Van Straten, Nepogodiev, D, Borakati, A, F Bath, M, H Yasin, I, Mclean, K, Arthur, T, Kovacevic, M, Delibegovic, S, Karamanliev, M, Swamad, M, Žebrák, R, Paramasivam, R, Martensen, A, M Larsen, H, Rädeker, L, E Frey, P, Kechagias, A, Venara, A, Duchalais, E, Ioannidis, A, Pasquali, S, Simioni, A, Farina, V, Podda, M, Lorenzon, L, Schaeff, V, Otto, A, Jakubauskas, M, R van Elst, T, Chu, M, Pvb, Fagan, I Wells, C, A Alagoa João, Juloski, J, Y El Kasmy El Kasmi, Espin-Basany, E, Clerc, D, Ciubotaru, C, Popescu, S, Yanishev, A, Lee, S, B Ozkan, B, A Yagız Sen, K Aktas, M, E Baki, B, Yüksek, B, Kamarajah, S, A Khaw, R, Mills, E, Goodson, R, Thakral, N, D Ablett, A, Adra, M, Kwek, I, M Khan, S, Quinn, P, R Manley, L, Badran, A, Ramjeeawon, A, Campbell, A, L Tan, H, S Rye, D, Rajaraman, N, G Norman, J, Vutipongsatorn, K, Solomou, G, Akhbari, 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M, Maciel, J, Cunha, M, J Aparício, D, Neves, J, Azevedo, J, Romano, M, Eiró, F, Romano, J, Monteiro, C, Claro, M, R Almeida, M, Peyroteo, M, D Machado, N, Capote, H, Ferreira, M, Sousa, X, Devesa, H, Cavadas, D, Guerreiro, I, Costa, M, Rosete, M, Salman, M, English, C, Mohammed, N, Litvin, A, V Ćuk, V, Mészárosová, K, Jaich, R, H De Lima, Brooks, S, Marx, M, M Nshalati Salvation, J García Cardo, Mora-Guzmán, I, J Sancho Muriel, U de Andres Olabarria, Muriel, P, C Jimenez Viñas, Alconchel, F, O Esteban Sinovas, C Fairén Oro, M López Otero, S Figueroa Jiménez, O Claramonte Bellmunt, J Martínez Caballero, Rubio-Pérez, I, M Aguilar-Martínez, M, J Segura-Sampedro, J, C Olmedo Moreno, D Negre Parra, M Estévez Diz, A, Martín-Balbuena, R, C Bustamante Recuenco, E Licardie Bolaños, R, Fernández, P, A Díaz Padillo, Forero-Torres, A, I Alberdi San Román, H Salvador Rosés, M Merayo Álvarez, P Villarejo Campos, C Lopes Moreira, C, P Uriol Peralta, M Serrano Navidad, Ripollés-Melchor, J, Garcea, A, 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L., Mccusker, C., Hlukha, L., Pike, G., Kamel, F., Thakkar, R., Donaldson, C., Campos, M. S., Bradbury, M., Osunronbi, T., Tam, L. Y. C., Kaabneh, A. K., Lawther, J., Fisher, P., Tribedi, T., Moosa, A., Ramdin, A., Goble, M., Downs, E., Wheldon, L., Baggus, E., Mandal, A., Nayeem, A., Ahmed, S., Fradley, W., Wilson, C., Gallagher, S., Criswell, T., Ward, J., Mukkavilli, A., Stubbs, B., Fordyce, W., Suchdev, N., Lim, S. W., Sookramanien, S. R., Chan, A., Bointas, G., Paul, M., Ward, K. L., Bagnall, M., Pherwani, S. A., Wang, K., Mitchell, L., Heyworth, J., Ayyar, S., Polson, R., Mackenzie, E., Doyle, N., Habib, Z., Zardab, M., Sartaj, F., Farooq, H., Tabibi, M., Drury, D. J., James, S. J., Barnett, R., Cahya, E., Lou, G., Coyle, M., Homyer, K., Zhu, L. Y., Woods, M., Chang, J., O'Callaghan, H., Suchett-Kaye, I., Mihailidis, T. H., Alawattegama, H., Seite, E., Barrett, A., Riordan, E., Lam, W., Dowdeswell, M., Mulvenna, C., Awokoya, O., Gurowich, L., Dhera, K., Hayat, S., Tincknell, L., Spazzapan, M., Teeling, F., Sysum, K., Latter, J., Latter, M., Khan, S., Woodmass, M., Hayden, H., Ali, Y., Husain, S., Arnold, A., Pedersen, A. C., Cunha, P., Ahmed, M., Al Zawawi, S., Kudva, V., Theodoropoulou, K., Miscampbell, M., Robinson, A. V., Johnston, J., Dharni, A., Lamb, S., Westerman, T., Evans, E., Campbell, L., Gillespie, M., Cheong, C. M., Kulathevanayagam, K., Varghese, A., Ike, S. I., Chu, T. S. M., Baljer, B., Mogg, J. A. W., Rai, P., Claireaux, H. A., Williams, M., Smillie, R., Goetz, J., Appleby, E., Fadipe, T., Vaughan-Burleigh, S., Jovaisaite, A., Shah, S. M., Khalid, N., Gutmann, D., Davison, S., Alame, Y. J., Syed, L., Owen, W. J., Ahsan, S. D., Anthony-Uzoeto, U., Hall, C. M., Zheng, S., Wynter, K., James, C., Sapre, D., Ghosh, R., Baird, J., Cockburn, L., Blackwood, O., Simpson, W., Jeong, S., Bishop, S., Bate, R., Hobson, C., Adam, A. H., Redclift, C., Do, J., Adeleye, O., Poli, F., Batterham, A., Brown, S., Parekh, J. N., Clay, W., Pieri, K., Jackson, A., Saxena, A., Gurung, B., Oyebola, T., O'Brien, F., Djeugam, B., Gardezi, S., Ul-Hasan, S., Martin-Hernandez, M. P., Sisley, M., Modi, S., Antakia, R., Elbayouk, A., Soh, Y. J., Mather, J., Yusuf, Z., Al-Sarraf, Z., Naja, M., Rassool, S. B., Convill, J., Nikookam, Y., Warsame, A., Pace, C., Kiandee, M., Ridwan, R., Carey, C., Hirri, F., Mcmillan, M. J. A., Ling, J. J., Pendelbury, L., Kerimzade, K., Tang, A., Howard, E. O., Humayun, S., Wadsworth, O. J., Tan, K., Abdelhameed, F., Haglund, C., Radnaeva, I., Hu, N., Rambhatla, S., Waldron, D., Madahar, P., Malik, S., Meney, L. C., Ibrahim, I., Kang, C. K., Chiu, J. Z. J., Livie, V., Ibrahim, B., Khalil, M., Pooley, G., Shishkin, B., Docherty, J., Southgate, A., Coomes, A., Mcgee, F., Flanagan, S., Tan, Q. J., Anwar, H., Clough, R., Chrisp, B., Cassels, J., Cross, G. W. V., Mercer, L., Mercer, C., Refalo, A., Hadley, R., Mctighe, A., Farrow, F., Brodie, A., Davis, G., Shah, D. R., Bowers, C., Patel, S., Morice, O., Burzic, A., Cheung, J., Shashidhara, A., Theodoraki, G., Birk, J., Ong, A., Ng, M. P. E., Wong, R. T. W., Maese, S., Yeap, B., Iqbal, Z., Melaugh, T., Perchard, W., Scurr, T., Campbell, E., Kelk, L., Ghosh, A., Gibbins, A., Mala, D., Loizidou, A., Hall, O., Mecia, L., Hew, C., Varathan, K., Tong, L., Chandrasekar, B., Buchanan, E., O'Connell, M., Kwak, S. Y., Ong, E. H., Gardner, S., Lim, J., Maden, C., Illahi, M., Tan, Z. X., Edwards, S., Stahl, R., Stahl, J., Hickman, A., Collett, D., Goolam-Mahomed, Z., Allen, B., Atiyah, A., Ahmad, H., Jones, J., Mcgregor, O., Ogundiya, E., Boulbadaoui, A., Kirnon-Jackman, O., Lim, Q. X., Peckham, H., Yeoh, T., Yong, S. Q., Chen, J. Y., Siva, S., Sam, Z. H., Gilani, M., Goh, Y. N., Muthukumar, M. G., Phillips, S., Tjoakarfa, J., Giri, A., Suresan, S., Thomas, P., Johnson, T. A., Williams, R. I., Rashid, A., Kushairi, A., Rais, A., James, A., Bugelli, M., Chechelnitskaya, Y., Sandhu, N., Tandon, R., Gray, M., Kumar, A., Ciurleo, C., Nyamali, I., Hiremath, S., Sinha, S., Chowdhary, M., Bradley, E., Mctiernan, M., Macdonald, S., Sharkey, S., Mclaughlin, N., Amey, C., Kraria, L., Skan, O., Kind, C., Tupper, P., Van Rhee, C., Honeyman, S. I., Menon, G., Jegatheeswaran, L., Madhavan, A., Warne, M., Malcolm, F. L., Lessware, T., Wilkerson, H. T., Chatterjee-Woolman, S., Yoong, A., Ahmed, W. U. R., Longshaw, A., Flannery, O., Green, R., Leaning, M., Cragg, J., Sharriff, H., Doherty, C., Kwan, K. W. L., Sanders-Crook, L., Bhatia, S., Eames, S., Lewis, F., Kirupananthan, P., Boh, Z. Y., Dass, S., Soma, A., Newton, A., Hill, M., Shafiq, Y., Brkljac, M., Boyce, L., English, W. J., Lam, S., Chipeta, C., Jain, C., Garofalidou, T., Novotny, S. A., Locke, S., Bowman, C., Begaj, A., Murphy, C., Radcliffe, K., Chong, J. T., Jeffrey, E., Chaudhury, N., Rajendran, K., Akbar, Z., Walters, B., Kulendrarajah, B., Tran, N., Shrestha, S., Parmar, S., Gallagher, C., Hennessy, L., Pentti, E., Badhrinarayanan, S., Fung, A., Mansoor, M., Kenny, R., Kan, P., Lee, D. E., Khosla, S., Samake, M., Shaban, F., Aftab, R., Gough, M., Woodburn, B., Vayalapra, S., Mcmurrugh, K., Jimulia, D., Deol, S., Pike, S., Embury-Young, Y., Patel, M., Kilgallon, E., Keating, R., Walsh, A., Khan, H., Logue, G., Orekoya, M., Alasmar, M., Charalambides, M., Llavall, A. C., Williamson, E., Bharwada, Y., Zearmal, S., Evans, H., Panikkar, M., de la Cruz, G., Caplan, J., Ruparelia, A., Tanvir, T., Soare, C., Pang, Y. L., Trotter, J., Zaidi, A., Thakrar, V., Pulickal, P., Ahmed, H., Parnell, J., Lennock, S., Ford, V., Brignall, R., O'Neill, D., Hanna, R., Kane, R., Nicola, M., Rajput, K., Xiao, Y., Michael, S., Wright, E., Juniper, S., Thompson, E., Hoskyns, L., Kanitkar, A., Ross, C., Unsworth, A., Rshaidat, H., Demarre, K., Chiang, A., Bareh, A., van Dellen, J., Faqihinejad, C., Gadhvi, A., Grant, R., Lewsey, J., Morris, A., Martin, H., Mcclarty, C., Sanyal, S., Alsaif, A., Palkhi, A., Bhopal, S., Burford, C., Huq, T., Irwin, E., Matthews, L., Ngu, W. S., Hosfield, T., Muneeb, F., Page, O., Zeb, E., Al-Azzawi, A., Mcintosh, J., Vucicevic, A., Hughes, M., Brooks, L., Fanibi, B., Dixon, M., Njoku, P., Morris, D., Jobson, J., Chowdhury, H., Joseph, N., Zulkefley, N., Hunt, G., Christodoulou, T., Wright, O., Soman, S., Jamal, M., Beqiri, S., Borgas, P., Christie, S., Pereira, F., Browne, S., Yiu, J., Dworkin, A., Brayley, J., Palmer, A., Charalambos, M., Jones, C. S., Toner, S., Cowden, R., Lee, L., Nicol, P., Holman, O., Imtiaz, M., Albert, V., Leung, S. P., Erotocritou, M., Stroud, R., Wilkin, R., Thomson, W., Mackee, L., Kler, A., Reynolds, L., Mohamed, S. H., Majeed, Y., Fakim, B., Jones, A., Liversedge, G., Carrington, Z., Windebank, J., Izzarina, A., Akbani, U., Craven, J., Aldarragi, A., Harding, S., Millward, A., Bedford, M., Gopalan, V., Midgen, A., Khadka, P., Cheng, O., Taneja, S., Manobharath, N., Kok, J. Y., Lim, D. W. E., Buick, T., Boland, M., Piya, S., Devlin, R., Fairfield, C. J., George, R. J., Rahi, M., Zaman, S., Hajiev, S., Ross, T., Crisp, E., Thompson, C., Charalambous, A., Hollywood, J. L., Hammond, R. F. L., Matthews, J., Mendonca, V., Spinty, J., Khan, K., Cheng, J., Glynn, N., Muhammad, U., Khan, M., Anderson, L., Mccormack, K., Mak, J., Patrawala, S., Milinkovic, N., Schofield, R., Chauhan, M., Hartley, L., Hind, J., Nelson, L., Ratnasingham, D., Whitehead, T., Dimitriadis, S., Marshall, K., Flint, E. J., Horner, C., Heybourne, A., Morgan, H., Wickstone, C., Panagiotou, D., O'Connell, E., Dean, K., Iqbal, R., Walsh, L., Yu, N., Rana, N., Massie, E., Ng, J., Jung, M., Lee, Y. D., Harris, M., White, S., Boev, B., Tonchev, P., Prochazka, V., Risko, J., Skalicky, A., Ravn, S., Ojakaar, A., Dorr-Harim, C., Koutserimpas, C., Giraudo, G., Armellini, A., Ruzzenente, A., Mazzeo, C., De Padua, C., Luc, A. R., Maroli, A., Vitali, M., Gusai, G. P., Quattromani, R., Virgilio, E., Berti, S., Di Mola, F. F., Papagni, V., Tuminello, F., Vittori, L., Longheu, A., Loche, G. A., Braccio, B., De Luca, E., Resta, G., Ancans, G., Tamosiunas, A., Petrulionis, M., Abdulrahman, N., van de Pas, K. G. H., Thomas, G., Brandsma, A. M., Davids, J., Rottier, S. J., de Roy van Zuidewijn, D., Hawkins, R., Ong, H. I., Li, Y., Desmond, B., Winstanley, J., Martins, M., Americano, M., Frade, S., Senhorinho, R., Peixoto, R., Alves-Vale, C., Lamas, M., O'Connor, D. B., Hoo, M., Gopaul, A., Scanlon, K., O'Dwyer, N., Jovanovic, M., Panyko, A., Van Vuuren, S., Centeno, A., Bernado, I. R., Senorans, M. P. G., Amor, L. G., Ramirez, A. C., Abrisqueta, J., Gomez, M. E., Arroyo, A., Cerdan, C., Romeu, N. G., Enriquez-Navascues, J. M., Collado-Roura, F., Curchod, P., Gaspar, S., Imadalou, L., Mutlu, D., Akyol, C., Uygur, F. A., Eray, I. C., Biyiklioglu, O., Cetin, M. F., Isik, A. E., Karip, B., Dogan, H., Sarigul, L., Tunc, E., Aydin, T., Bodur, S., Karabulut, K., Francis, A. A., Al-hadithi, A., Lau, I. S. F., Smith, E., Mahapatra, S., Mcauliffe, O., Imam, L., Akram, B., Hossaini, S., Davies, R., Ko, M., Collins, J., Pandya, A., Reilly, S., Archer, J., Livie, J., Chaudhry, F. A., Ntakomyti, E., Diallo, R., Bylinski, T., Wright, J., Masiha, E., Tung, J., Shirazi, B., Neilson, A., Epton, S., Patel, N., Trussell, S., Couldrey, A., and Donnelly, C.
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operative ,Male ,postoperative discharge ,Postoperative Complications ,0302 clinical medicine ,Colostomy ,CRITERIA ,Prospective Studies ,Bowel function ,Colectomy ,IMAGINE ,stoma ,intestines ,Proctectomy ,Ileostomy ,digestive, oral, and skin physiology ,patient discharge ,colorectal surgery, hospital discharge, bowel function ,RECOVERY ,Middle Aged ,adult ,colostomy ,elective surgical procedures ,female ,follow-up studies ,humans ,ileostomy ,ileus ,male ,middle aged ,multivariate analysis ,patient readmission ,patient safety ,postoperative complications ,prospective studies ,recovery of function ,colectomy ,proctectomy ,Patient Discharge ,Colorectal surgery ,ileus - - discharge - bowel function - elective - colorectal surgery ,Elective Surgical Procedures ,030220 oncology & carcinogenesis ,Female ,030211 gastroenterology & hepatology ,Patient Safety ,Cohort study ,safety ,Adult ,medicine.medical_specialty ,Ileus ,Patient Readmission ,defecation ,03 medical and health sciences ,medicine ,Hospital discharge ,Humans ,colorectal surgery ,colorectal resection ,Colorectal resection ,defecation, postoperative complications, colorectal surgery, intestines, patient discharge, patient readmission, safety, surgical procedures, operative, colorectal resection, ileus ,business.industry ,Recovery of Function ,Odds ratio ,medicine.disease ,digestive system diseases ,surgical procedures ,Surgery ,Multivariate Analysis ,Defecation ,business ,Follow-Up Studies - Abstract
Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien-Dindo classification system.A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) days respectively (P 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110).Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients.El íleo es frecuente tras la cirugía colorrectal y se asocia con un aumento del riesgo de las complicaciones postoperatorias. Identificar las características de una recuperación normal del tránsito y la idoneidad para el alta hospitalaria es una tarea difícil. Este estudio examinó la seguridad del alta hospitalaria antes del restablecimiento de la función intestinal. MÉTODOS: Se llevó a cabo un estudio de cohortes prospectivo y multicéntrico a través de una red de colaboración internacional. Se incluyeron pacientes adultos sometidos a resección electiva colorrectal entre enero y abril 2018. El objetivo principal fue el reingreso hospitalario durante los 30 primeros días tras la intervención. Se utilizó un análisis de regresión multivariable para evaluar el impacto del momento del alta en función del restablecimiento de la función intestinal. El objetivo secundario fue las complicaciones postoperatorias en los primeros 30 días después de la cirugía, valoradas mediante el sistema de clasificación de Clavien-Dindo.Se incluyeron en el análisis 3.288 pacientes, de los cuales 301 (9,2%) fueron dados de alta antes del restablecimiento de la función intestinal. La mediana de la estancia hospitalaria de los pacientes dados de alta antes y después del restablecimiento de la función intestinal fue 5 (rango intercuartílico: 4-7) y 7 (6-8) días, respectivamente (P 0,001). No hubo diferencias significativas en las tasas de reingreso entre estos grupos (6,6% versus 8,0%; P = 0,499), y este resultado se mantuvo en el análisis multivariable tras el ajuste por diferencias basales (razón de opotunidades, odds ratio, OR 0,90; i.c. del 95% 0,55-1,46, P = 0,659). Las tasas de complicaciones postoperarorias fueron similares en aquellos dados de alta antes o después del restablecimiento de la función intestinal (complicaciones menores: 34,7% versus 39,5%; complicaciones mayores 3,3% versus 3,4%; P = 0,110). CONCLUSIÓN: Dar de alta antes del restablecimiento de la función intestinal tras cirugía colorrectal electiva parece ser seguro en pacientes debidamente seleccionados.
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- 2020
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23. Prevalence of depressive symptoms in elderly cancer patients receiving chemotherapy and influencing factors
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Pinar Soysal, Aziz Karaoglu, Feyza Mutlay, Murat Keser, Hülya Ellidokuz, Seher Nazli Kazaz, Huseyin Salih Semiz, and Elif Atag
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education.field_of_study ,medicine.medical_specialty ,business.industry ,Population ,Cancer ,Disease ,medicine.disease ,03 medical and health sciences ,Psychiatry and Mental health ,Distress ,Social support ,0302 clinical medicine ,Quality of life ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,Geriatric Depression Scale ,030212 general & internal medicine ,Geriatrics and Gerontology ,education ,business ,Gerontology ,Depression (differential diagnoses) - Abstract
Background Depression is one of the most prevalent causes of distress in the geriatric population. The purpose of this study was to examine the prevalence of depressive symptoms in elderly cancer patients and to determine the possible associated factors. Methods Cancer patients 65 years or older and on active chemotherapy completed the Yesavage Geriatric Depression Scale. We examined the relationship of depressive symptoms with age, gender, marital status, educational background, type of cancer, stage of disease, comorbidities, types of treatment for cancer, the duration after diagnosis of cancer, social support, and pain status. Results The study included 170 patients with a mean age of 71 years, and 47.1% were women. The prevalence of a high depressive symptom score was 19.4%. Of the patients who had a high depressive symptom score based on the Yesavage Geriatric Depression Scale, 18.2% had already been diagnosed with depression and used antidepressants. The mean pain score was significantly higher in patients who had a high depressive symptom score compared to others (P = 0.012). Conclusion The prevalence of depressive symptoms in elderly cancer patients receiving chemotherapy was similar to that in the geriatric population without cancer. It was also consistent with previous studies on elderly cancer population. Pain was found to be a factor related to depressive symptoms. The prevalence of depression may be reduced by pain control. The treatment of depression may both improve the patient's quality of life and enhance their compliance with treatment.
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- 2018
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24. On the application of hole‐selective MoOxas full‐area rear contact for industrial scale p‐type c‐Si solar cells
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Nasser, Hisham, primary, Es, Fırat, additional, Zolfaghari Borra, Mona, additional, Semiz, Emel, additional, Kökbudak, Gamze, additional, Orhan, Efe, additional, and Turan, Raşit, additional
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- 2020
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25. Response to LTE “Re: Does Gadoterate Meglumine Cause Gadolinium Retention in the Brain of Children? A Case–Control Study”
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Topcuoglu, Elif Dilara, primary, Topcuoglu, Osman Melih, additional, Semiz Oysu, Aslıhan, additional, and Bukte, Yasar, additional
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- 2020
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26. Response to LTE 'Re: Does Gadoterate Meglumine Cause Gadolinium Retention in the Brain of Children? A Case–Control Study'
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Osman Melih Topcuoglu, Aslıhan Semiz Oysu, Yasar Bukte, and Elif Dilara Topcuoglu
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chemistry ,business.industry ,Gadolinium ,Medicine ,chemistry.chemical_element ,Radiology, Nuclear Medicine and imaging ,business ,Nuclear medicine ,GADOTERATE MEGLUMINE - Published
- 2020
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27. Does Gadoterate Meglumine Cause Gadolinium Retention in the Brain of Children? A Case–Control Study
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Topcuoglu, Elif Dilara, primary, Topcuoglu, Osman Melih, additional, Semiz Oysu, Aslihan, additional, and Bukte, Yasar, additional
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- 2019
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28. Depression and hopelessness in pre‐clinical medical students
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Coskun, Ozlem, primary, Ocalan, Ali Ozgurcan, additional, Ocbe, Cetin Batuhan, additional, Semiz, Huseyin Omer, additional, and Budakoglu, Irem, additional
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- 2019
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29. Pyrolytically grown indium sulfide sensitized zinc oxide nanowires for solar water splitting
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Pelin Komurcu, Nurdan Demirci Sankir, Mehmet Sankir, Alp Eren Gurol, Fatma Merve Alkan, Erkan Aydin, Levent Semiz, and Emre Kaan Can
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chemistry.chemical_classification ,Materials science ,Sulfide ,Inorganic chemistry ,Nanowire ,chemistry.chemical_element ,Heterojunction ,Zinc ,Condensed Matter Physics ,chemistry ,Absorption (electromagnetic radiation) ,Indium ,Visible spectrum ,Chemical bath deposition - Abstract
Zinc oxide (ZnO) nanowires, sensitized with spray pyrolyzed indium sulfide, were obtained by chemical bath deposition. The XRD analysis indicated dominant evolution of hexagonal ZnO phase. Significant gain in photoelectrochemical current using ZnO nanowires is largely accountable to enhancement of the visible light absorption and the formation of heterostructure. The maximum photoconversion efficiency of 2.77% was calculated for the indium sulfide sensitized ZnO nanowire photoelectrodes. (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
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- 2015
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30. Vitamin D status in children with attention-deficit-hyperactivity disorder
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Ali Evren Tufan, Cemalettin Gunes, Fatih Demircioğlu, Mehmet Tosun, Murat Semiz, Sevil Bilir Goksugur, and Mervan Bekdas
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Pediatrics ,medicine.medical_specialty ,Serum vitamin D level ,business.industry ,mental disorders ,Pediatrics, Perinatology and Child Health ,medicine ,Vitamin D and neurology ,Attention deficit hyperactivity disorder ,Adhd group ,medicine.disease ,business ,Early onset - Abstract
Background Attention-deficit–hyperactivity disorder (ADHD), one of the most common psychiatric disorders of childhood, has an early onset, affecting 2–18% of children worldwide. The etiopathogenesis of ADHD is obscure. In recent studies, a low level of vitamin D has been found in association with many disorders as well as in neuropsychiatric diseases. The aim of this study was therefore to investigate serum vitamin D level in pediatric ADHD patients. Methods A total of 60 ADHD patients and 30 healthy controls were included in the study. The age of both groups was in the 7–18-year-old range. Serum 25-OH-vitamin D, calcium, phosphorus and alkaline phosphatase were investigated. Results Serum 25-OH-vitamin D was found to be significantly lower in children and adolescents with ADHD compared to healthy controls, and no significant differences were found between the groups in terms of other variables. 25-OH-vitamin D level in the ADHD group and control group was, respectively, 20.9 ± 19.4 ng/mL and 34.9 ± 15.4 ng/mL (P = 0.001). Conclusion There is an association between lower 25-OH-vitamin D concentration and ADHD in childhood and adolescence. To the authors' knowledge this is the first study to investigate the relationship between vitamin D and ADHD in children.
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- 2014
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31. Prevalence of depressive symptoms in elderly cancer patients receiving chemotherapy and influencing factors
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Atag, Elif, primary, Mutlay, Feyza, additional, Soysal, Pinar, additional, Semiz, Huseyin S., additional, Kazaz, Seher N., additional, Keser, Murat, additional, Ellidokuz, Hulya, additional, and Karaoglu, Aziz, additional
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- 2018
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32. Hierarchical order statistics filtering for fast bi-dimensional EMD
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Anil Celebi, Oguzhan Urhan, and Serkan Semiz
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General Computer Science ,Computer science ,business.industry ,020208 electrical & electronic engineering ,Order statistic ,Window (computing) ,020206 networking & telecommunications ,Pattern recognition ,02 engineering and technology ,Hilbert–Huang transform ,Electronic, Optical and Magnetic Materials ,Set partitioning in hierarchical trees ,0202 electrical engineering, electronic engineering, information engineering ,Artificial intelligence ,Electrical and Electronic Engineering ,business - Abstract
A hierarchical approach for fast bi-dimensional empirical mode decomposition (B-EMD) is proposed. The presented approach utilizes an efficient window...
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- 2016
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33. High performance chromium (VI) removal from water by polyacrylonitrile-co-poly (2-ethyl hexylacrylate) and polyaniline nanoporous membranes
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Nurdan Demirci Sankir, Ali Usanmaz, Selcuk Bozkır, Mehmet Sankir, and Levent Semiz
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Materials science ,Polymers and Plastics ,Polyacrylonitrile ,chemistry.chemical_element ,Nanotechnology ,General Chemistry ,Technological research ,chemistry.chemical_compound ,Chromium ,Chemical engineering ,chemistry ,Polyaniline ,Materials Chemistry ,Nanoporous membrane - Abstract
Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [108T099]
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- 2012
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34. Patient with 45,X karyotype and severe virilization occult Y sequences
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Ender Duzcan, Ugur Koltuksuz, Serap Semiz, Füsun Düzcan, N. Lale Satiroglu-Tufan, C. Nur Semerci, and Nergul Corduk
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Gynecology ,medicine.medical_specialty ,medicine.diagnostic_test ,Virilization ,Gonadoblastoma ,Karyotype ,Biology ,Y chromosome ,medicine.disease ,Occult ,Testis determining factor ,Hypospadias ,Pediatrics, Perinatology and Child Health ,medicine ,medicine.symptom ,Fluorescence in situ hybridization - Published
- 2012
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35. Serum cortisol and dehydroepiandrosterone-sulfate levels in schizophrenic patients and their first-degree relatives
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Fatih Kilicli, Orhan Doğan, Murat Semiz, and Osman Yildirim
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endocrine system ,medicine.medical_specialty ,General Neuroscience ,General Medicine ,Disease ,medicine.disease ,Pathophysiology ,Psychiatry and Mental health ,chemistry.chemical_compound ,Endocrinology ,Dehydroepiandrosterone sulfate ,Neurology ,chemistry ,Schizophrenia ,Internal medicine ,Genetic predisposition ,medicine ,Neurology (clinical) ,First-degree relatives ,Psychology ,hormones, hormone substitutes, and hormone antagonists ,Serum cortisol ,Diagnosis of schizophrenia - Abstract
Aims: Alterations in cortisol and dehydroepiandrosterone sulfate (DHEA-S) levels are thought to play a role in the pathophysiology of neuropsychiatric disorders, including schizophrenia. The aim of this study was to investigate the role of serum cortisol and DHEA-S in the pathophysiology of schizophrenia. Methods: Sixty schizophrenic patients, 70 healthy first-degree relatives, and 60 healthy volunteers were included. Sociodemographic characteristics, data regarding disease duration and severity, as well as ongoing and previous drug use were recorded. Serum cortisol and DHEA-S levels were measured. Results: Serum cortisol and DHEA-S levels were significantly higher in the schizophrenia group compared with the first-degree relatives and controls (P
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- 2011
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36. Echocardiographic Epicardial Fat Thickness Is Associated with Carotid Intima-Media Thickness in Patients with Metabolic Syndrome
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Mehmet Mustafa Can, Vecih Oduncu, Ismet Dindar, Ender Semiz, Cihan Sengul, Taylan Akgun, Olcay Ozveren, Aysegul Sunbul, and Cihan Cevik
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medicine.medical_specialty ,Waist ,business.industry ,Anthropometry ,medicine.disease ,Epicardial fat ,Insulin resistance ,Blood pressure ,Intima-media thickness ,Internal medicine ,cardiovascular system ,medicine ,Cardiology ,Radiology, Nuclear Medicine and imaging ,In patient ,cardiovascular diseases ,Metabolic syndrome ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background: Carotid intima-media thickness (CIMT) is a potential indicator of subclinical atherosclerosis in patients with metabolic syndrome (MetS). Epicardial fat thickness (EFT) is suggested as a new cardiometabolic risk factor. We investigated the association between EFT and CIMT in patients with MetS. Methods: Forty patients with MetS were compared with 40 age- and sex-matched subjects without MetS in terms of echocardiographic EFT, CIMT, anthropometric measurements, and metabolic profile in this cross-sectional study. Results: The waist circumference, total and LDL-cholesterol, fasting glucose, triglycerides, systolics and diastolic blood pressure levels, hs-CRP, and homeostasis model assessment index for insulin resistance (HOMA-IR) were significantly increased in patients with MetS. The EFT and CIMT were also increased significantly in patients with MetS compared to controls (7.2 ± 2 mm vs. 5.7 ± 1.9 mm; P = 0.001, 0.74 ± 0.1 mm vs. 0.59 ± 0.1 mm; P < 0.01, respectively). Echocardiographic EFT was the only independent predictor of CIMT in the multivariate analysis (standardized β coefficient = 0.74, P < 0.001). Conclusion: EFT is associated with increased CIMT in patients with MetS. (Echocardiography 2011;28:853-858)
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- 2011
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37. Assessment of Atrial Conduction Time in Patients with Coronary Artery Ectasia
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Vecih Oduncu, Mehmet Can, Cihan Cevik, Aysegul Sunbul, Olcay Ozveren, Fethi Kilicarslan, Ismet Dindar, Ender Semiz, and Cihan Sengul
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medicine.medical_specialty ,business.industry ,Coronary artery ectasia ,Atrial fibrillation ,General Medicine ,medicine.disease ,Coronary artery disease ,medicine.anatomical_structure ,Atrial conduction ,Tissue Doppler echocardiography ,Internal medicine ,Ectasia ,Heart rate ,medicine ,Cardiology ,Cardiology and Cardiovascular Medicine ,business ,Artery - Abstract
Background: Coronary artery ectasia (CAE) is associated with increased sympathetic activity, plasma levels of inflammatory markers, and oxidative stress. These factors can also cause arrhythmias such as atrial fibrillation. Atrial conduction abnormalities in patients with CAE have not been investigated in terms of atrial electromechanical delay obtained by tissue Doppler echocardiography. Methods: Ninety patients with pure CAE (n = 30), nonobstructive coronary artery disease (NO-CAD) (n = 30), and angiographically normal coronary arteries “controls” (n = 30) were compared in terms of electrocardiographic P-wave measurements, echocardiographic atrial electromechanical coupling (AEC) parameters, and interatrial conduction delay. Results: The mean left atrium diameter in the CAE group was similar to the NO-CAD group but significantly greater than the control group (3.62 ± 0.28 vs 3.46 ± 0.32 vs 3.41 ± 0.31 cm, P = 0.021). P maximum and P-wave dispersion were significantly increased in the CAE group compared to the NO-CAD group and the control group (108.6 ± 6.6 vs 97.9 ± 6.6 vs 93.5 ± 6.2, P = 0.0001; 34.4 ± 7.6 vs 23.2 ± 7.8 vs 19.4 ± 7.7 ms, P < 0.0001). Mitral AEC, septal AEC, and tricuspid AEC were significantly higher in the CAE group than the NO-CAD group and the control group (68 ± 4.5 vs 57 ± 4.5 vs 53 ± 4.6 ms, P < 0.0001; 50.7 ± 7 vs 42.7 ± 7 vs 41.7 ± 7.2 ms, P = 0.0001; 47 ± 6.7 vs 39.1 ± 6.7 vs 38.1 ± 6.6 ms, P < 0.0001). Interatrial conduction delay was significantly increased in the CAE group compared to the NO-CAD group and the control group (21 ± 5.5 vs 17.8 ± 5.6 vs 15 ± 5.6 ms, P < 0.0001).The correlation analysis demonstrated that the interatrial conduction delay and P-wave dispersion (Pd) were positively correlated with number of ectatic segments (ESN) (r = 0.41, P = 0.024 vs r = 0.49, P = 0.006). Stepwise multiple linear regression analysis revealed that the ESN was the only independent determinants of interatrial conduction delay (P = 0.024). Conclusion: Pd and interatrial conduction delay are prolonged in patients with CAE compared to NO-CAD patients and the healthy controls. (PACE 2011; 34:1468–1474)
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- 2011
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38. Manipulation of VOC emissions with methyl jasmonate and carrageenan in the evergreen conifer Pinus sylvestris and evergreen broadleaf Quercus ilex
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Ülo Niinemets, Gürkan Semiz, James D. Blande, Juha Heijari, Kani Isik, and Jarmo K. Holopainen
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Methyl jasmonate ,biology ,Jasmonic acid ,Monoterpene ,Green leaf volatiles ,Scots pine ,Plant Science ,General Medicine ,Evergreen ,biology.organism_classification ,Terpene ,chemistry.chemical_compound ,chemistry ,Botany ,Plant hormone ,Ecology, Evolution, Behavior and Systematics - Abstract
Plant defence can be induced by exposing plants to the plant hormone jasmonic acid (JA) or its volatile ester, methyl jasmonate (MeJA). Carrageenans (Carr) - sulphated D-galactans extracted from red algae - can also induce plant defences. In this study, the effects of exogenous MeJA and Carr application (concentration 300 and 12.7 μmol, respectively) on volatile emissions from two widespread evergreen woody species, Pinus sylvestris (nine Turkish and one Finnish provenance) and Quercus ilex (Italian provenance) were investigated. We collected headspace samples from seedlings and analysed the quality and quantity of volatile compounds emitted by treated and control plants. In total, 19 monoterpenes, 10 sesquiterpenes, 10 green leaf volatiles (GLVs) and two aromatic compounds were emitted by P. sylvestris from all the provenances studied. Foliar MeJA application clearly affected the volatile profiles of trees from all the provenances. Effects of Carr were genotype specific. In Q. ilex, emissions of sesquiterpenes, GLVs and the homoterpene (E)-DMNT were all induced by MeJA application. However, emissions of most constitutively emitted monoterpenes were significantly reduced. Carr application also led to a significant reduction in monoterpene emissions, but without corresponding increases in other emissions. Our results indicate that exogenously applied MeJA and Carr can both significantly modify the volatile profiles of P. sylvestris and Q. ilex, but also that there are important provenance- and species-specific differences in the overall degree of elicitation and compositions of elicited compounds.
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- 2011
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39. Drug interaction potential of the seed extract ofUrtica urensL. (dwarf Nettle)
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Merve Bayav, Asli Semiz, Pelin Tekin, Hizlan H. Agus, and Alaattin Sen
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Pharmacology ,food.ingredient ,biology ,Urtica ,Cytochrome P450 ,Glutathione ,CYP2E1 ,Pharmacognosy ,biology.organism_classification ,Urticaceae ,chemistry.chemical_compound ,food ,chemistry ,Biochemistry ,In vivo ,Urtica urens ,biology.protein - Abstract
Dwarf nettle (Urtica urens) seed extract was examined in vivo in the rat for its potential to modulate drug metabolizing enzymes including aminopyrine N-demethylase (APND; CYP2C6), aniline 4-hydroxylase (A4H; CYP2E1), nitrosodimethylamine N-demethylase (NDMA-ND; CYP2E1) erythromycin N-demethylase (ERND; CYP3A1) CYP2D1/2 and glutathione S-transferase (GST). RT-PCR data and western blotting studies clearly demonstrated that CYP2C6 and CYP2E1 mRNA levels were substantially increased after Urtica treatment, while the level of CYP3A1 mRNA decreased and that of CYP2D1/2 remained unchanged. Urtica treatment significantly induced GST activity in the liver, lung and kidney (66-, 46- and 31-fold, respectively) while decreasing that of APND (35-, 61- and 94-fold) and NDMA-ND (23, 28 and 54-fold). ERND activity in liver was reduced 45-fold, but increased in the lung and kidney (78- and 144-fold) after Urtica treatment. These results indicate that Urtica seed extract may have the potential to inhibit and/or induce the metabolism of certain co-administered drugs.
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- 2009
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40. Lack of association between DRD3 gene polymorphism and response to clozapine in Turkish schizoprenia patients
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Ümit Başar Semiz, Cengiz Basoglu, I. Ömer Barlas, M. Emin Erdal, Hasan Herken, M. Ertan Ay, Mesut Cetin, and Özcan Uzun
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Turkey ,genotype ,medicine.medical_treatment ,Glycine ,Biology ,Pharmacology ,Bioinformatics ,behavioral disciplines and activities ,Association ,Cellular and Molecular Neuroscience ,Limbic system ,male ,Dopamine receptor D3 ,Genotype ,Serine ,medicine ,controlled study ,human ,Polymorphism ,Antipsychotic ,DNA extraction ,Clozapine ,Gene ,Genetics (clinical) ,DNA Primers ,Dopamine D3 receptor gene (DRD3) ,Polymorphism, Genetic ,Base Sequence ,adult ,Dopaminergic ,article ,Receptors, Dopamine D3 ,treatment response ,major clinical study ,Psychiatry and Mental health ,female ,medicine.anatomical_structure ,priority journal ,DNA polymorphism ,Case-Control Studies ,Schizophrenia ,Gene polymorphism ,psychologic assessment ,Antipsychotic Agents ,medicine.drug - Abstract
It is hypothesized that molecular components of dopaminergic system, especially the dopamine D3 receptor gene (DRD3), may play a crucial role in the pathophysiology of schizophrenia, because it is abundant in the limbic system of the brain and it binds antipsychotic drugs. Several groups attempted to find an association between a serine-to-glycine polymorphism of the DRD3 gene (Ser9Gly) and schizophrenia; however, the results were inconsistent. In this study, we aimed to investigate the relationship of the Serine/Glycine polymorphism of the DRD3 gene with therapeutic response to clozapine treatment between Turkish schizophrenia patients (N = 92) and healthy controls (N = 100). Genotype groups were comparable in BPRS, SAPS, SANS analysis of response to clozapine. Our results suggest that an association between the Ser/Gly polymorphism of DRD3 gene and response to clozapine in Turkish schizophrenia patients is unlikely to exist. © 2008 Wiley-Liss, Inc.
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- 2009
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41. Two Cases of Cushing’s Syndrome Due to Overuse of Topical Steroid in the Diaper Area1
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Yasemin Işık Balcı, Şeniz Ergin, Maşallah Candemir, Aziz Polat, and Serap Semiz
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medicine.medical_specialty ,S syndrome ,business.industry ,medicine.medical_treatment ,Diaper area ,Immunosuppression ,Dermatology ,medicine.disease ,Disseminated cytomegalovirus infection ,Surgery ,Cushing syndrome ,Pediatrics, Perinatology and Child Health ,medicine ,Clobetasol propionate ,Adverse effect ,business ,Topical steroid ,medicine.drug - Abstract
Topical use of corticosteroids may cause immunosuppression and iatrogenic Cushing's syndrome via hypothalamic-pituitary-adrenal axis. We report two cases with iatrogenic Cushing's syndrome with different clinical outcomes due to abuse of same potent topical steroid clobetasol propionate. One of them died because of fatal disseminated cytomegalovirus infection. The other patient recovered completely. Physicians and parents should be informed about the adverse effects of such potent topical corticosteroids and physicians should prescribe less potent agents, especially during infancy.
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- 2008
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42. Assessment of P-Wave Dispersion on 12-Lead Electrocardiography in Students Who Exercise Regularly
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Ismail Sakar, Osman Kahyaoglu, Olcay Semiz, Pinar Pazarli, Sevin Altinkaynak, and Mustafa Yildiz
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Adult ,Male ,medicine.medical_specialty ,Physical fitness ,Sensitivity and Specificity ,Body Mass Index ,Electrocardiography ,Sex Factors ,Heart Conduction System ,Heart Rate ,Internal medicine ,Heart rate ,medicine ,Humans ,Statistical dispersion ,Exercise physiology ,Students ,Exercise ,business.industry ,Atrial fibrillation ,General Medicine ,medicine.disease ,Pulse pressure ,Blood pressure ,Physical Fitness ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business ,Body mass index - Abstract
Background: P-wave dispersion, an electrocardiographic marker, is an independent predictor of atrial fibrillation. P-wave dispersion is associated with inhomogeneous and discontinuous propagation of sinus impulses. The aim of this study was to investigate P-wave dispersion in students who apply for registration to School of Physical Education and Sports. Methods: Totally 984 students (810 boys [mean age: 19.8 ± 2.0 years] and 174 girls [mean age: 19.0 ± 1.8 years]) who applied for registration to School of Physical Education and Sports with a training history of some years were included in the study. P-wave duration was calculated in all 12 leads of the surface electrocardiography, which were simultaneously recorded. The difference between P maximum and P minimum durations was defined as P-wave dispersion. Results: Age, body mass index (BMI), systolic blood pressure, diastolic blood pressure, P-wave maximal duration, and P-wave dispersion were increased in boys as compared with girls. Of age (P = 0.53), systolic blood pressure (P = 0.42), diastolic blood pressure (P = 0.50), pulse pressure (P = 0.73), gender, heart rate, and BMI tested with univariate linear regression analysis in all subjects; only gender (P < 0.001), BMI (P = 0.01), and heart rate (P = 0.02) were associated with P-wave dispersion (F = 5.16, P < 0.001, R2= 0.03). Conclusions: P-wave dispersion was increased in boys as compared with girls who exercise regularly. P-wave dispersion is affected by gender, BMI, and heart rate in healthy students.
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- 2008
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43. Nightmare disorder, dream anxiety, and subjective sleep quality in patients with borderline personality disorder
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Ümit Başar Semiz, Cengiz Basoglu, Mesut Cetin, and Servet Ebrinç
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Adult ,Male ,medicine.medical_specialty ,Nightmare disorder ,Dissociative Experiences Scale ,Comorbidity ,Dissociative Disorders ,Anxiety ,Life Change Events ,Pittsburgh Sleep Quality Index ,Borderline Personality Disorder ,Risk Factors ,Sleep Initiation and Maintenance Disorders ,Interview, Psychological ,mental disorders ,medicine ,Humans ,Dissociative disorders ,Psychiatry ,Borderline personality disorder ,General Neuroscience ,General Medicine ,Middle Aged ,medicine.disease ,Dreams ,Nightmare ,Psychiatry and Mental health ,Neurology ,Female ,Neurology (clinical) ,medicine.symptom ,Psychology ,Anxiety disorder - Abstract
Aims: The aims of the present study were to examine the rate of nightmare disorder (ND) and to determine the levels of dream anxiety and subjective sleep quality in patients with borderline personality disorder (BPD). Another aim was to determine whether dream anxiety was associated with childhood trauma, dissociative experiences, and subjective sleep disturbance in BPD patients. Finally, the hypothesis as to whether BPD patients with ND exhibited a more severe clinical profile than those without ND, was also tested. Methods: A total of 88 borderline patients and 100 age- and sex-matched healthy control subjects were assessed using the Structured Clinical Interview for DSM-III-R Personality Disorders, Structured Clinical Interview for DSM-IV Axis I Disorders, Van Dream Anxiety Scale, Pittsburgh Sleep Quality Index, Dissociative Experiences Scale, and Traumatic Experiences Checklist. Subjects with codiagnoses that could affect sleep were not included. Results: BPD patients suffered a significantly greater rate of nightmares, elevated levels of dream anxiety, and disturbed sleep quality than did controls. In the borderline group, heightened dream anxiety was correlated with higher rates of early traumatic experiences and dissociative symptoms, and impaired sleep quality. Furthermore, borderline patients with ND exhibited greater psychopathology as compared to those without ND in terms of several clinical characteristics. Conclusions: The present study provides support for a strong association between BPD, distressing nightmares, and subjective sleep quality. Recognition and management of dream and sleep disturbances in BPD patients might lead to improvements in their global clinical picture.
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- 2008
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44. Dissociation and alexithymia among men with alcoholism
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Bilge Evren, Ercan Dalbudak, Ümit Başar Semiz, Duran Çakmak, Cuneyt Evren, and Vedat Sar
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Adult ,Male ,medicine.medical_specialty ,Personality Inventory ,Turkey ,Dissociative Experiences Scale ,Comorbidity ,Dissociative Disorders ,Anxiety ,Toronto Alexithymia Scale ,Patient Admission ,Sex Factors ,Alexithymia ,medicine ,Humans ,Affective Symptoms ,Dissociative disorders ,Psychiatry ,medicine.diagnostic_test ,General Neuroscience ,Beck Depression Inventory ,General Medicine ,Middle Aged ,medicine.disease ,Michigan Alcoholism Screening Test ,Alcoholism ,Psychiatry and Mental health ,Neurology ,Female ,Neurology (clinical) ,medicine.symptom ,Personality Assessment Inventory ,Psychology ,Follow-Up Studies - Abstract
Aim: The aim of the present study was to evaluate the relationship between alexithymia and dissociation among men with alcoholism. Methods: Participants were 176 patients consecutively admitted to the inpatient unit of a addiction treatment center. The Toronto Alexithymia Scale, the Symptom Checklist-Revised, the Dissociative Experiences Scale, the Beck Depression Inventory, the Spielberger State–Trait Anxiety Inventory, and the Michigan Alcoholism Screening Test were administered to all participants. Results: Fifty-three patients were considered as having alexithymia. The alexithymic group had a significantly higher rate of dissociative taxon members (patients with pathological dissociation; 62.3%) according to Bayesian probability. Trait anxiety, overall psychiatric symptom severity, and pathological dissociation predicted alexithymia on covariance analysis. A multivariate analysis of covariance demonstrated that these predictors were related only to difficulty of identifying feelings, whereas trait anxiety was a significant covariant for difficulty of expressing feelings as well. Conclusion: Alexithymic phenomena are interrelated with dissociation and chronic anxiety among men with alcoholism. The relevance of this triad for prevention and treatment of alcoholism deserves interest in further research.
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- 2008
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45. Influence of demographic and clinical characteristics of actinic keratosis patients on illness perceptions and readiness to increase sun protection behaviours: an exploratory study
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Akarsu, Sevgi, primary, Ozbagcivan, Ozlem, additional, Ilknur, Turna, additional, Semiz, Fatma, additional, and Fetil, Emel, additional
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- 2017
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46. Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta‐Analysis
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Dujic, T, primary, Zhou, K, additional, Yee, SW, additional, van Leeuwen, N, additional, de Keyser, CE, additional, Javorský, M, additional, Goswami, S, additional, Zaharenko, L, additional, Hougaard Christensen, MM, additional, Out, M, additional, Tavendale, R, additional, Kubo, M, additional, Hedderson, MM, additional, van der Heijden, AA, additional, Klimčáková, L, additional, Pirags, V, additional, Kooy, A, additional, Brøsen, K, additional, Klovins, J, additional, Semiz, S, additional, Tkáč, I, additional, Stricker, BH, additional, Palmer, CNA, additional, 't Hart, LM, additional, Giacomini, KM, additional, and Pearson, ER, additional
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- 2017
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47. Effectiveness of a naturally derived insecticide, spinosad, against the pine processionary mothThaumetopoea wilkinsoni Tams (Lepidoptera: Thaumetopoeidae) under laboratory conditions
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Atila Yanikoglu, Kani Isik, Gürkan Semiz, and Huseyin Cetin
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Insecticides ,Veterinary medicine ,Larva ,Biological pest control ,Spinosad ,General Medicine ,Moths ,Biology ,Pinus ,biology.organism_classification ,Lethal Dose 50 ,Toxicology ,Lepidoptera genitalia ,Drug Combinations ,Biopesticide ,Insect Science ,medicine ,Animals ,Instar ,Macrolides ,PEST analysis ,Agronomy and Crop Science ,medicine.drug ,Thaumetopoeidae - Abstract
The pine processionary moth Thaumetopoea wilkinsoni Tams is a serious pest on pine trees in southwestern Turkey. The efficacy of a naturally derived insecticide, spinosad, on fourth-fifth instar larvae of T. wilkinsoni was studied under laboratory conditions. The product exhibited strong larvicidal activity and at doses above 5 mg litre(-1) caused > 90% mortality in the fourth-fifth larval stages of the species after 72 h. At 72 h the LD50 and LD90 values were 3.26 and 5.69 mg litre(-1) respectively. The results showed that spinosad is highly effective on T. wilkinsoni larvae.
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- 2006
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48. Association between paraoxonase-1 activity and lipid peroxidation indicator levels in people living in the antalya region with angiographically documented coronary artery disease
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Ender Semiz, Ayşe Yeşim Göçmen, and Saadet Gumuslu
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medicine.medical_specialty ,biology ,Apolipoprotein B ,business.industry ,Cholesterol ,Paraoxonase ,nutritional and metabolic diseases ,General Medicine ,PON1 ,Lipid peroxidation ,chemistry.chemical_compound ,Endocrinology ,Aryldialkylphosphatase ,chemistry ,Internal medicine ,biology.protein ,TBARS ,Medicine ,lipids (amino acids, peptides, and proteins) ,Cardiology and Cardiovascular Medicine ,business ,Lipoprotein - Abstract
Background: Paraoxonase-1 (PON1) is a high-density lipoprotein (HDL)-associated enzyme capable of hydrolyzing lipid peroxides. Thus, PON1 plays a preventing role in atherosclerosis by protecting against lipid peroxidation. Hypothesis: The incidence of coronary artery disease (CAD) is high in the Turkish population, and many risk factors have been studied as determinants of CAD. In Turkish people living in the Antalya region, we aimed to determine serum PON1 activity and its relation to lipoproteins and lipid peroxidation markers. Methods: We measured the activity of serum PON1 together with concentrations of a variety of lipid constituents—total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C), HDL cholesterol (HDL-C), triglycerides (TG), apolipoprotein (apo) A-I, apoB, and lipid peroxidation indicators (conjugated diene [CD] and thiobarbituric acid-reactive substances [TBARS])—in 108 patients with CAD and 64 healthy subjects (controls). Results: We found that the PON1 activity was significantly reduced in patients with CAD (222.37 ± 11.31 IU/l)compared with controls (331.75 ± 20.98 IU/l). These patients had significantly lower HDL-C, PON1/HDL-C, apoA-I, PON1/ApoA-I, and ApoA-I/ApoB, and higher LDL-C, TC/HDL-C, LDL-C/HDL-C, apoB, CD and TBARS than did controls. Total cholesterol and apoA-I concentrations were significantly higher in women than in men in both groups. After multiple logistic regression analysis, TBARS (odds ratio [OR] 568.87; p = 0.000), age (OR 1.10; p = 0.000), gender (OR 4.58; p = 0.008), apoA-I/apoB (OR 0.046; p = 0.003), and PON1/apoA-I (OR 0.58; p = 0.007) were independently indicative of the presence of CAD. Conclusions: This is the first report of decreased serum PON1 activity and increased lipid peroxidation indicators (CD and TBARS) of patients with CAD living in Antalya, Turkey. Our results indicate that TBARS levels, age, gender, apoA-1/ApoB, and PON1/apoA-I ratios are important markers of CAD.
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- 2004
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49. Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules
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Chuanyou Zhang, Jin Park, Anil Chawla, Sabina Semiz, Paul S. Furcinitti, Michael P. Czech, Sarah M. Nicoloro, and John D. Leszyk
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Monosaccharide Transport Proteins ,Recombinant Fusion Proteins ,medicine.medical_treatment ,Glucose uptake ,Molecular Sequence Data ,Kinesins ,Muscle Proteins ,macromolecular substances ,Microtubules ,General Biochemistry, Genetics and Molecular Biology ,Wortmannin ,Mice ,Phosphatidylinositol 3-Kinases ,chemistry.chemical_compound ,Bacterial Proteins ,Microtubule ,Adipocytes ,medicine ,Animals ,Insulin ,Enzyme Inhibitors ,Transport Vesicles ,Molecular Biology ,Cells, Cultured ,Oligonucleotide Array Sequence Analysis ,Glucose Transporter Type 4 ,General Immunology and Microbiology ,biology ,General Neuroscience ,Cell Membrane ,Glucose transporter ,Biological Transport ,Articles ,Intracellular Membranes ,Fibroblasts ,Rats ,Cell biology ,Androstadienes ,Luminescent Proteins ,Insulin receptor ,chemistry ,biology.protein ,Kinesin ,hormones, hormone substitutes, and hormone antagonists ,GLUT4 ,Signal Transduction - Abstract
Insulin stimulates glucose uptake in muscle and adipose cells by mobilizing intracellular membrane vesicles containing GLUT4 glucose transporter proteins to the plasma membrane. Here we show in live cultured adipocytes that intracellular membranes containing GLUT4-yellow fluorescent protein (YFP) move along tubulin-cyan fluorescent protein-labeled microtubules in response to insulin by a mechanism that is insensitive to the phosphatidylinositol 3 (PI3)-kinase inhibitor wortmannin. Insulin increased by several fold the observed frequencies, but not velocities, of long-range movements of GLUT4-YFP on microtubules, both away from and towards the perinuclear region. Genomics screens show conventional kinesin KIF5B is highly expressed in adipocytes and this kinesin is partially co-localized with perinuclear GLUT4. Dominant-negative mutants of conventional kinesin light chain blocked outward GLUT4 vesicle movements and translocation of exofacial Myc-tagged GLUT4-green fluorescent protein to the plasma membrane in response to insulin. These data reveal that insulin signaling targets the engagement or initiates the movement of GLUT4-containing membranes on microtubules via conventional kinesin through a PI3-kinase-independent mechanism. This insulin signaling pathway regulating KIF5B function appears to be required for GLUT4 translocation to the plasma membrane.
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- 2003
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50. Vitamin D status in children with attention-deficit-hyperactivity disorder
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Göksügür, Sevil Bilir, Tufan, Ali Evren, Semiz, Murat, Güneş, Cemalettin, Bekdaş, Mervan, Tosun, Mehmet, and Demircioğlu, Fatih
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children ,mental disorders ,vitamin D ,attention-deficit-hyperactivity disorder - Abstract
Bekdas, Mervan/0000-0003-2469-9509; Tufan, ALI EVREN/0000-0001-5207-6240 WOS: 000342836700020 PubMed: 24417979 BackgroundAttention-deficit-hyperactivity disorder (ADHD), one of the most common psychiatric disorders of childhood, has an early onset, affecting 2-18% of children worldwide. The etiopathogenesis of ADHD is obscure. In recent studies, a low level of vitamin D has been found in association with many disorders as well as in neuropsychiatric diseases. The aim of this study was therefore to investigate serum vitamin D level in pediatric ADHD patients. MethodsA total of 60 ADHD patients and 30 healthy controls were included in the study. The age of both groups was in the 7-18-year-old range. Serum 25-OH-vitamin D, calcium, phosphorus and alkaline phosphatase were investigated. ResultsSerum 25-OH-vitamin D was found to be significantly lower in children and adolescents with ADHD compared to healthy controls, and no significant differences were found between the groups in terms of other variables. 25-OH-vitamin D level in the ADHD group and control group was, respectively, 20.9 19.4ng/mL and 34.9 +/- 15.4ng/mL (P = 0.001). ConclusionThere is an association between lower 25-OH-vitamin D concentration and ADHD in childhood and adolescence. To the authors' knowledge this is the first study to investigate the relationship between vitamin D and ADHD in children.
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- 2014
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