1. The Movement Disorder Society Nonmotor Rating Scale: Initial Validation Study
- Author
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Chaudhuri, K Ray, Schrag, Anette, Weintraub, Daniel, Rizos, Alexandra, Rodriguez-Blazquez, Carmen, Mamikonyan, Eugenia, Martinez-Martin, Pablo, Chaudhuri, K. Ray, Rodriguez‐Blazquez, Carmen, Martinez‐Martin, Pablo, International Parkinson and Movement Disorder Society, United Kingdom Clinical Research Collaboration, National Institute for Health Research (Reino Unido), and University of Pennsylvania (Estados Unidos)
- Subjects
Adult ,Male ,0301 basic medicine ,medicine.medical_specialty ,Nonmotor symptoms ,Movement disorders ,Parkinson's disease ,Intraclass correlation ,Scales ,Severity of Illness Index ,Article ,Disability Evaluation ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Cronbach's alpha ,Rating scale ,Interquartile range ,Activities of Daily Living ,medicine ,Humans ,Aged ,business.industry ,Reproducibility of Results ,Parkinson Disease ,Middle Aged ,medicine.disease ,Nonmotor fluctuations ,body regions ,Inter-rater reliability ,Cross-Sectional Studies ,030104 developmental biology ,Standard error ,Neurology ,Parkinson’s disease ,Female ,Neurology (clinical) ,medicine.symptom ,business ,030217 neurology & neurosurgery - Abstract
Erratum to: “The Movement Disorder Society Nonmotor Rating Scale: Initial Validation Study”, by Ray Chaudhuri et al. (Mov Disord 2020; 35: 116-133). Mov Disord. 2020 Jan;35(10):116-133. https://doi.org/10.1002/mds.28266 Background: The Movement Disorder Society-sponsored Nonmotor Rating Scale is an update of the existing Parkinson's disease Nonmotor Symptoms Scale modified to address some limitations in Nonmotor Symptoms Scale scoring, structure, and symptom coverage. Methods: PD patients were recruited from movement disorder centers in an international, multicenter study. The Movement Disorder Society Nonmotor Rating Scale, consisting of 13 domains plus a subscale for nonmotor fluctuations, was rater administered, along with the Nonmotor Symptoms Scale and other clinical assessments. Standard reliability and validity testing were conducted. Results: Four hundred and two PD patients were recruited (mean age ± standard deviation, 67.42 ± 9.96 years; mean age at PD onset ± standard deviation, 59.27 ± 10.67 years; median Hoehn and Yahr stage 2 (interquartile range 2-3). Data quality was satisfactory for all Movement Disorder Society Nonmotor Rating Scale domains except sexual (6.7% missing data). There were no floor or ceiling effects for the Movement Disorder Society Nonmotor Rating Scale and nonmotor fluctuations total score; domains had no ceiling effects, but some floor effects (13.5%-83.5%). The Movement Disorder Society Nonmotor Rating Scale and nonmotor fluctuations total score internal consistency were acceptable (average Cronbach's alpha, 0.66 and 0.84, respectively); interrater reliability was excellent (intraclass correlation coefficient, >0.95); for test-retest reliability, the intraclass correlation coefficient was 0.84 for the Movement Disorder Society Nonmotor Rating Scale and 0.70 for Movement Disorder Society nonmotor fluctuations total score, and precision was excellent for the Movement Disorder Society Nonmotor Rating Scale (standard error of measurement, 25.30) and fair for nonmotor fluctuations (standard error of measurement, 7.06). Correlations between Movement Disorder Society Nonmotor Rating Scale score and the corresponding Nonmotor Symptoms Scale and Movement Disorder Society UPDRS scores were high. There were no significant sex or age effects. The Movement Disorder Society Nonmotor Rating Scale score increased with increasing PD duration, disease severity, and PD medication dose (all P
- Published
- 2019