1. Disturbed sleep in individuals with idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF): Melatonin assessment as a biological marker
- Author
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Christelle Gamez, Laurent Hugueville, Soafara Andrianome, Maité Hanot-Roy, Brahim Selmaoui, René de Seze, and Kelly Blazy
- Subjects
0301 basic medicine ,medicine.medical_specialty ,animal structures ,Physiology ,Biophysics ,Urine ,Melatonin ,Pittsburgh Sleep Quality Index ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Medicine ,Radiology, Nuclear Medicine and imaging ,Circadian rhythm ,business.industry ,Epworth Sleepiness Scale ,General Medicine ,Sleep in non-human animals ,Idiopathic environmental intolerance ,6. Clean water ,3. Good health ,030104 developmental biology ,Endocrinology ,Analysis of variance ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Individuals who suffer from idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) complain of a variety of adverse health effects. Troubled sleep remains a recurrent and common symptom in IEI-EMF individuals. Melatonin, a circadian hormone, plays a major role in the sleep process. In this study, we compared levels of melatonin between a sensitive group (IEI-EMF, n = 30) and a non-sensitive control group (non IEI-EMF, n = 25) without exposure to electromagnetic sources. Three questionnaires were used to evaluate the subjective quality and sleep quantity: the Epworth Sleepiness Scale, the Pittsburgh Sleep Quality Index and the Spiegel Sleep Inventory. Melatonin was quantified in saliva and its major metabolite 6-sulfatoxymelatonin (aMT6s) in urine. Melatonin levels were compared by a two-way analysis of variance at various times between the control and IEI-EMF group. Despite significantly different sleep scores between the two groups, with a lower score in the IEI-EMF group (P 0.05) and urine aMT6s (P > 0.05). Bioelectromagnetics. 37:175-182, 2016. © 2016 Wiley Periodicals, Inc.
- Published
- 2016