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Your search keyword '"Radujkovic, Aleksandar"' showing total 11 results
Start Over Author "Radujkovic, Aleksandar" Publisher wiley
11 results on '"Radujkovic, Aleksandar"'

1. Outcomes of CMML patients undergoing allo‐HCT are significantly worse compared to MDS—a study of the CMWP of the EBMT

Author

Rovó, Alicia, primary, Gras, Luuk, additional, Piepenbroek, Brian, additional, Kröger, Nicolaus, additional, Reinhardt, H. Christian, additional, Radujkovic, Aleksandar, additional, Blaise, Didier, additional, Kobbe, Guido, additional, Niityvuopio, Riitta, additional, Platzbecker, Uwe, additional, Sockel, Katja, additional, Hunault‐Berger, Mathilde, additional, Cornelissen, J. J., additional, Forcade, Edouard, additional, Bourhis, Jean Henri, additional, Chalandon, Yves, additional, Kinsella, Francesca, additional, Nguyen‐Quoc, Stéphanie, additional, Maertens, Johan, additional, Elmaagacli, Ahmet, additional, Mordini, Nicola, additional, Hayden, Patrick, additional, Raj, Kavita, additional, Drozd‐Sokolowska, Joanna, additional, de Wreede, Liesbeth C., additional, McLornan, Donal P., additional, Robin, Marie, additional, Yakoub‐Agha, Ibrahim, additional, and Onida, Francesco, additional

Published
2023
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2. Outcomes after allogeneic hematopoietic cell transplant in patients diagnosed with blast phase of myeloproliferative neoplasms: A retrospective study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

Author

Ortí, Guillermo, primary, Gras, Luuk, additional, Zinger, Nienke, additional, Finazzi, Maria Chiara, additional, Sockel, Katja, additional, Robin, Marie, additional, Forcade, Edouard, additional, Avenoso, Daniele, additional, Kröger, Nicolaus, additional, Finke, Jürgen, additional, Radujkovic, Aleksandar, additional, Hunault‐Berger, Mathilde, additional, Schroyens, Wilfried, additional, Zuckerman, Tsila, additional, Bourhis, Jean Henri, additional, Chalandon, Yves, additional, Bloor, Adrian, additional, Schots, Rik, additional, de Wreede, Liesbeth C., additional, Drozd‐Sokolowska, Joana, additional, Raj, Kavita, additional, Polverelli, Nicola, additional, Czerw, Tomasz, additional, Hernández‐Boluda, Juan Carlos, additional, McLornan, Donal, additional, and Yakoub‐Agha, Ibrahim, additional

Published
2023
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4. Outcomes of allogeneic haematopoietic cell transplantation for chronic neutrophilic leukaemia: A combined CIBMTR / CMWP of EBMT analysis

Author

Dholaria, Bhagirathbhai, primary, Radujkovic, Aleksandar, additional, Estrada‐Merly, Noel, additional, Sirait, Tiarlan, additional, Kim, Soyoung, additional, Hernández‐Boluda, Juan Carlos, additional, Czerw, Tomasz, additional, Hayden, Patrick J., additional, Kansagra, Ankit, additional, Ho, Vincent T., additional, Nishihori, Taiga, additional, Shaughnessy, Paul, additional, Scott, Bart, additional, Nakamura, Ryotaro, additional, Oran, Betul, additional, Kharfan‐Dabaja, Mohamed, additional, Savani, Bipin N., additional, McLornan, Donal, additional, Yakoub‐Agha, Ibrahim, additional, and Saber, Wael, additional

Published
2022
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5. Submyeloablative total body irradiation‐based conditioning and allogeneic stem cell transplantation in high‐risk myeloma with early progression after up‐front autologous transplantation

Author

Mai, Elias K., primary, Schmitt, Thomas, additional, Radujkovic, Aleksandar, additional, König, Laila, additional, Goldschmidt, Hartmut, additional, Ho, Anthony D., additional, Luft, Thomas, additional, Müller‐Tidow, Carsten, additional, Dreger, Peter, additional, Hegenbart, Ute, additional, and Schönland, Stefan O., additional

Published
2021
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6. Outcome of allogeneic haematopoietic stem cell transplantation in myeloproliferative neoplasm, unclassifiable: a retrospective study by the Chronic Malignancies Working Party of the EBMT

Author

McLornan, Donal P., primary, Malpassuti, Vittoria, additional, Lippinkhof‐Kozijn, Anne, additional, Potter, Victoria, additional, Beelen, Dietrich, additional, Bunjes, Donald, additional, Sengeloev, Henrik, additional, Radujkovic, Aleksandar, additional, Passweg, Jakob, additional, Chalandon, Yves, additional, Kröger, Nicolaus, additional, Wulf, Gerald G., additional, Johansson, Jan‐Erik, additional, Ciceri, Fabio, additional, Bornhäuser, Martin, additional, Holler, Ernst, additional, Guffroy, Blandine, additional, Martin, Sonja, additional, Neubauer, Andreas, additional, Gramatski, Martin, additional, Robin, Marie, additional, Iacobelli, Simona, additional, Hayden, Patrick, additional, Hernández Boluda, Juan C., additional, Czerw, Tomasz, additional, and Yakoub‐Agha, Ibrahim, additional

Published
2020
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7. Expression of CDKN1C in the bone marrow of patients with myelodysplastic syndrome and secondary acute myeloid leukemia is associated with poor survival after conventional chemotherapy

Author

Radujkovic, Aleksandar, primary, Dietrich, Sascha, additional, Andrulis, Mindaugas, additional, Benner, Axel, additional, Longerich, Thomas, additional, Pellagatti, Andrea, additional, Nanda, Kriti, additional, Giese, Thomas, additional, Germing, Ulrich, additional, Baldus, Stefan, additional, Boultwood, Jacqueline, additional, Ho, Anthony D., additional, Dreger, Peter, additional, and Luft, Thomas, additional

Published
2016
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9. Imatinib‐supplemented myeloablative total‐body irradiation/cyclophosphamide conditioning prior to allogeneic stem cell transplantation as consolidation treatment in patients with blast crisis of chronic myeloid leukemia

Author

Radujkovic, Aleksandar, primary, Dreger, Peter, additional, Hegenbart, Ute, additional, Buss, Eike C., additional, Luft, Thomas, additional, Ho, Anthony D., additional, Fruehauf, Stefan, additional, and Topaly, Julian, additional

Published
2014
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11. Statin-based endothelial prophylaxis and outcome after allogeneic stem cell transplantation.

Author

Pabst C, Schreck N, Benner A, Hegenbart U, Schönland S, Radujkovic A, Schmitt M, Müller-Tidow C, Orsatti L, Dreger P, and Luft T

Subjects
Humans, Neoplasm Recurrence, Local, Retrospective Studies, Transplantation, Homologous, Tryptophan, Graft vs Host Disease, Hematopoietic Stem Cell Transplantation, Hydroxymethylglutaryl-CoA Reductase Inhibitors
Abstract

Background: Allogeneic haematopoietic stem cell transplantation (alloSCT) often remains the only curative therapy for hematologic malignancies. Although the management of transplant-associated adverse events considerably improved over the last decades, nonrelapse mortality (NRM) remains a challenge, and endothelial dysfunction was identified as a major contributor to NRM., Methods: Statin-based endothelial prophylaxis (SEP) has been implemented in the standard of care in our transplant centre to reduce NRM caused by endothelial injury. Here, we retrospectively analysed the impact of SEP on clinical outcome in a cohort of 347 alloSCT patients., Results: SEP (n = 209) was associated with significantly reduced NRM (hazard ratio 0.61, 95% CI 0.38-0.96) and better overall survival (OS) after acute graft-versus-host disease (HR 0.59, 95% CI 0.37-0.93). Subgroup analyses showed that the NRM benefit was mainly found in patients with an intermediate endothelial activation and stress index (EASIX), while relapse risk was not affected. On day 100 post-alloSCT, patients receiving SEP had significantly higher levels of the rate-limiting enzyme of tryptophan metabolism, indoleamine 2,3-dioxygenase (IDO), higher kynurenine to tryptophan ratios as a proxy of IDO activity and tended to have lower levels of the endothelial injury marker ST2 (p = .055). No significant differences in interferon-gamma or IL18 levels were observed. These biomarker signatures suggest that the beneficial effects of SEP might be mediated by both endothelial protection and immunomodulation., Conclusions: Together, these data suggest that SEP improves NRM and OS post-alloSCT in particular in patients with intermediate endothelial risk and provide first mechanistic clues about its potential mode of action., (© 2022 The Authors. European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation.)

Published
2023
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