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28 results on '"Qin, Na"'

1. Identification of genetically predicted DNA methylation markers associated with non–small cell lung cancer risk among 34,964 cases and 448,579 controls

Author

Zhao, Xiaoyu, primary, Yang, Meiqi, additional, Fan, Jingyi, additional, Wang, Mei, additional, Wang, Yifan, additional, Qin, Na, additional, Zhu, Meng, additional, Jiang, Yue, additional, Gorlova, Olga Y., additional, Gorlov, Ivan P., additional, Albanes, Demetrius, additional, Lam, Stephen, additional, Tardón, Adonina, additional, Chen, Chu, additional, Goodman, Gary E., additional, Bojesen, Stig E., additional, Landi, Maria Teresa, additional, Johansson, Mattias, additional, Risch, Angela, additional, Wichmann, H.‐Erich, additional, Bickeböller, Heike, additional, Christiani, David C., additional, Rennert, Gad, additional, Arnold, Susanne M., additional, Brennan, Paul, additional, Field, John K., additional, Shete, Sanjay, additional, Le Marchand, Loïc, additional, Liu, Geoffrey, additional, Hung, Rayjean J., additional, Andrew, Angeline S., additional, Kiemeney, Lambertus A., additional, Zienolddiny, Shanbeh, additional, Grankvist, Kjell, additional, Johansson, Mikael, additional, Caporaso, Neil E., additional, Woll, Penella J., additional, Lazarus, Philip, additional, Schabath, Matthew B., additional, Aldrich, Melinda C., additional, Patel, Alpa V., additional, Davies, Michael P. A., additional, Ma, Hongxia, additional, Jin, Guangfu, additional, Hu, Zhibin, additional, Amos, Christopher I., additional, Shen, Hongbing, additional, and Dai, Juncheng, additional

Published
2023
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2. Integrative analyses of N6‐methyladenosine‐associated single‐nucleotide polymorphisms (m6A‐SNPs) identify tumor suppressor gene AK9 in lung cancer

Author

Hua, Tingting, primary, Zhang, Chang, additional, Fu, Yating, additional, Qin, Na, additional, Liu, Su, additional, Chen, Congcong, additional, Gong, Linnan, additional, Ma, Huimin, additional, Ding, Yue, additional, Wei, Xiaoxia, additional, Jin, Chenying, additional, Jin, Chen, additional, Zhu, Meng, additional, Zhang, Erbao, additional, Dai, Juncheng, additional, and Ma, Hongxia, additional

Published
2023
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4. Gene amplification‐driven RNA methyltransferase KIAA1429 promotes tumorigenesis by regulating BTG2 via m6A‐YTHDF2‐dependent in lung adenocarcinoma

Author

Zhang, Chang, primary, Sun, Qi, additional, Zhang, Xu, additional, Qin, Na, additional, Pu, Zhening, additional, Gu, Yayun, additional, Yan, Caiwang, additional, Zhu, Meng, additional, Dai, Juncheng, additional, Wang, Cheng, additional, Li, Ni, additional, Jin, Guangfu, additional, Ma, Hongxia, additional, Hu, Zhibin, additional, Zhang, Erbao, additional, Tan, Fengwei, additional, and Shen, Hongbing, additional

Published
2022
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5. Functional characterization and clinical significance of super‐enhancers in lung adenocarcinoma

Author

Jiang, Xiangxiang, primary, Qin, Na, additional, Hua, Tingting, additional, Wei, Xiaoxia, additional, Li, Yuancheng, additional, Chen, Congcong, additional, Gong, Linnan, additional, Liu, Su, additional, Wang, Cheng, additional, Yin, Rong, additional, Jiang, Yue, additional, Dai, Juncheng, additional, Xu, Lin, additional, Shen, Hongbing, additional, and Ma, Hongxia, additional

Published
2022
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9. Hypomethylation‐activated cancer‐testis gene SPANXC promotes cell metastasis in lung adenocarcinoma

Author

Wang, Xuewei, primary, Ju, Sihan, additional, Chen, Yao, additional, Qian, Qufei, additional, Yan, Caiwang, additional, Chen, Shuaizhou, additional, Chang, Yuting, additional, Xu, Yide, additional, Ma, Zijian, additional, Zhang, Chang, additional, Qin, Na, additional, Gu, Yayun, additional, Wang, Cheng, additional, Zhang, Erbao, additional, and Hu, Zhibin, additional

Published
2019
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10. Comprehensive characterization of cancer‐testis genes in testicular germ cell tumor

Author

Chang, Yuting, primary, Wang, Xuewei, additional, Xu, Yide, additional, Yang, Liu, additional, Qian, Qufei, additional, Ju, Sihan, additional, Chen, Yao, additional, Chen, Shuaizhou, additional, Qin, Na, additional, Ma, Zijian, additional, Dai, Juncheng, additional, Ma, Hongxia, additional, Jin, Guangfu, additional, Zhang, Erbao, additional, Wang, Cheng, additional, and Hu, Zhibin, additional

Published
2019
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11. Circulating CD137 + CD8 + T cells accumulate along with increased functional regulatory T cells and thoracic tumour burden in lung cancer patients

Author

Nong, Jingying, primary, Wang, Jinghui, additional, Gao, Xin, additional, Zhang, Qi, additional, Yang, Bin, additional, Yan, Zhuohong, additional, Wang, Xiaojue, additional, Yi, Ling, additional, Wang, Qunhui, additional, Gao, Yuan, additional, Hu, Aimin, additional, Qin, Na, additional, Wei, Panjian, additional, Zhang, Hongtao, additional, and Zhang, Shucai, additional

Published
2019
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12. Gene amplification derived a cancer‐testis long noncoding RNA PCAT6 regulates cell proliferation and migration in hepatocellular carcinoma

Author

Chen, Shuaizhou, primary, Chen, Yao, additional, Qian, Qufei, additional, Wang, Xuewei, additional, Chang, Yuting, additional, Ju, Sihan, additional, Xu, Yide, additional, Zhang, Chang, additional, Qin, Na, additional, Ding, Hui, additional, Gu, Yayun, additional, Han, Jing, additional, Wang, Cheng, additional, Zhang, Erbao, additional, and Hu, Zhibin, additional

Published
2019
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14. Cancer-testis genePIWIL1promotes cell proliferation, migration, and invasion in lung adenocarcinoma

Author

Xie, Kaipeng, primary, Zhang, Kai, additional, Kong, Jing, additional, Wang, Cheng, additional, Gu, Yayun, additional, Liang, Cheng, additional, Jiang, Tingting, additional, Qin, Na, additional, Liu, Jibin, additional, Guo, Xuejiang, additional, Huo, Ran, additional, Liu, Mingxi, additional, Ma, Hongxia, additional, Dai, Juncheng, additional, and Hu, Zhibin, additional

Published
2017
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17. Potentially functional variants in lncRNAs are associated with breast cancer risk in a Chinese population

Author

Jiang, Yue, primary, Du, Fangzhi, additional, Chen, Fei, additional, Qin, Na, additional, Jiang, Zhu, additional, Zhou, Jin, additional, Jiang, Tao, additional, Pu, Zhening, additional, Cheng, Yue, additional, Chen, Jiaping, additional, Dai, Juncheng, additional, Ma, Hongxia, additional, Jin, Guangfu, additional, Hu, Zhibin, additional, Yu, Hao, additional, and Shen, Hongbing, additional

Published
2017
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20. ChemInform Abstract: Palladium-Catalyzed Suzuki-Miyaura Coupling of Aryl Sulfamates with Arylboronic Acids

Author

Ren-Hao Li, Li-Xiong Shao, Qin-Na Ma, and Zhan-Yong Wang

Subjects
Coupling (electronics), chemistry.chemical_compound, chemistry, Potassium, Aryl, chemistry.chemical_element, General Medicine, Combinatorial chemistry, Catalysis, Palladium
Abstract

A newly synthesized NHC-Pd(II)-morpholine complex shows efficient catalytic activity toward Suzuki—Miyaura coupling of aryl sulfamates (I) with arylboronic acids (II) or potassium phenyltrifluoroborate (IV).

Published
2014

28. Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls.

Author

Zhao X, Yang M, Fan J, Wang M, Wang Y, Qin N, Zhu M, Jiang Y, Gorlova OY, Gorlov IP, Albanes D, Lam S, Tardón A, Chen C, Goodman GE, Bojesen SE, Landi MT, Johansson M, Risch A, Wichmann HE, Bickeböller H, Christiani DC, Rennert G, Arnold SM, Brennan P, Field JK, Shete S, Le Marchand L, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Zienolddiny S, Grankvist K, Johansson M, Caporaso NE, Woll PJ, Lazarus P, Schabath MB, Aldrich MC, Patel AV, Davies MPA, Ma H, Jin G, Hu Z, Amos CI, Shen H, and Dai J

Subjects
Adult, Humans, DNA Methylation, Genome-Wide Association Study, Epigenesis, Genetic, Biomarkers, CpG Islands, Carcinoma, Non-Small-Cell Lung genetics, Lung Neoplasms genetics
Abstract

Background: Although the associations between genetic variations and lung cancer risk have been explored, the epigenetic consequences of DNA methylation in lung cancer development are largely unknown. Here, the genetically predicted DNA methylation markers associated with non-small cell lung cancer (NSCLC) risk by a two-stage case-control design were investigated., Methods: The genetic prediction models for methylation levels based on genetic and methylation data of 1595 subjects from the Framingham Heart Study were established. The prediction models were applied to a fixed-effect meta-analysis of screening data sets with 27,120 NSCLC cases and 27,355 controls to identify the methylation markers, which were then replicated in independent data sets with 7844 lung cancer cases and 421,224 controls. Also performed was a multi-omics functional annotation for the identified CpGs by integrating genomics, epigenomics, and transcriptomics and investigation of the potential regulation pathways., Results: Of the 29,894 CpG sites passing the quality control, 39 CpGs associated with NSCLC risk (Bonferroni-corrected p ≤ 1.67 × 10 -6 ) were originally identified. Of these, 16 CpGs remained significant in the validation stage (Bonferroni-corrected p ≤ 1.28 × 10 -3 ), including four novel CpGs. Multi-omics functional annotation showed nine of 16 CpGs were potentially functional biomarkers for NSCLC risk. Thirty-five genes within a 1-Mb window of 12 CpGs that might be involved in regulatory pathways of NSCLC risk were identified., Conclusions: Sixteen promising DNA methylation markers associated with NSCLC were identified. Changes of the methylation level at these CpGs might influence the development of NSCLC by regulating the expression of genes nearby., Plain Language Summary: The epigenetic consequences of DNA methylation in lung cancer development are still largely unknown. This study used summary data of large-scale genome-wide association studies to investigate the associations between genetically predicted levels of methylation biomarkers and non-small cell lung cancer risk at the first time. This study looked at how well larotrectinib worked in adult patients with sarcomas caused by TRK fusion proteins. These findings will provide a unique insight into the epigenetic susceptibility mechanisms of lung cancer., (© 2023 American Cancer Society.)

Published
2024
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