9 results on '"Qianyi Wan"'
Search Results
2. Development and external validation of a nomogram for individualized adjuvant imatinib duration for high‐risk gastrointestinal stromal tumors: A multicenter retrospective cohort study
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Ruolin Liu, Yingxin Wu, Jin Gong, Rui Zhao, Li Li, Qianyi Wan, Nan Lian, Xiaoding Shen, Lin Xia, Yuhou Shen, Haitao Xiao, Xiaoting Wu, Yi Chen, Ying Cen, and Xuewen Xu
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adjuvant imatinib ,gastrointestinal stromal tumors ,high risk ,individualized treatment duration ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Introduction The main emphasis of the research about adjuvant imatinib for high‐risk gastrointestinal stromal tumors (GISTs) is prolonging the treatment duration and ignores the heterogeneous that 10‐year recurrence rates ranged from about 20%–100%. Thus, this study evaluated the effect of different durations of adjuvant imatinib on outcomes in high‐risk GISTs to explore the feasibility of individual treatment. Methods We analyzed 855 high‐risk GIST patients from three centers who underwent macroscopically complete resection between December 2007 and September 2020. The patients were divided into training (n =564) and two validation cohorts (n = 238 and53) based on their source. Recurrence‐free survival (RFS) was the primary point. Cox multivariate analysis was used to develop the nomogram. C‐index, time‐dependent area under the curves, and calibration plots were used to assess the performance of the nomogram. Results Univariate analysis showed that longer adjuvant imatinib was significantly associated with better 5‐year RFS (p
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- 2022
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3. Low Skeletal Muscle Mass and the Incidence of Delirium in Hospitalized Older Patients: A Systematic Review and Meta-Analysis of Observational Studies
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Yuhou Shen, Qianyi Wan, Rui Zhao, Yi Chen, Lin Xia, Yutao Wu, Shuomeng Xiao, Yong Wang, Lihao Zhao, Tao Li, and Xiaoting Wu
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Medicine - Abstract
Background. Both low skeletal muscle mass and delirium are prevalent in older hospitalized patients, while their associations are unclear. This systematic review and meta-analysis aim to investigate the associations between low skeletal muscle mass and the incidence of delirium in hospitalized patients. Methods. The PubMed, Web of Science, and Embase were searched for relevant studies published before May 2022, and we conducted this systematic review and meta-analysis according to the PRISMA and MOOSE guidelines. The summary odds ratios (OR) and 95% confidence intervals (CI) were estimated, and subgroup analyses were also conducted according to the age and major surgeries. Results. Finally, nine studies with 3 828 patients were included. The pooled result showed no significant association between low skeletal muscle mass and the incidence of delirium (OR 1.69, 95% CI 0.85 to 2.52). However, sensitivity analysis suggested that one study caused a significant alteration of the summary result, and the meta-analysis of the remaining 8 studies showed that low skeletal muscle mass was significantly associated with an 88% increased incidence of delirium (OR 1.88, 95% CI 1.43 to 2.33). Furthermore, subgroup analyses indicated that low skeletal muscle mass was associated with a higher incidence of delirium in patients ≥75 years old or undergoing major surgeries instead of those
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- 2023
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4. Sarcopenia and adverse health‐related outcomes: An umbrella review of meta‐analyses of observational studies
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Lin Xia, Rui Zhao, Qianyi Wan, Yutao Wu, Yong Zhou, Yong Wang, Yaping Cui, Xiaoding Shen, and Xiaoting Wu
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AMSTAR ,GRADE ,health‐related outcomes ,sarcopenia ,umbrella review ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Objective The purpose of this umbrella review was to assess the associations between sarcopenia and adverse health‐related outcomes. Design An umbrella review of meta‐analyses of observational studies. Setting and Participants Patients with sarcopenia and controls without sarcopenia were included. Measures The PubMed, Web of Science and Embase were searched for relevant systematic review and meta‐analysis. AMSTAR and GRADE system were used for methodological quality and evidence quality assessments, respectively. Results Totally 54 outcomes extracted from 30 meta‐analyses were analyzed. Twenty out of 21 prognostic outcomes indicated that sarcopenia was significantly associated with poorer prognosis of gastric cancer, hepatocellular cancer, urothelial cancer, head and neck cancer, hematological malignancy, pancreatic cancer, breast cancer, colorectal cancer, lung cancer, esophageal cancer, and ovarian cancer. Besides, 10 out of 16 postoperative outcomes suggested that sarcopenia significantly increased the risk of multiple postoperative complications and prolonged the length of hospitalization of patients with digestive cancer. In age‐related outcomes, sarcopenia significantly increased the risk of dysphagia, cognitive impairment, fractures, falls, hospitalization, and all‐cause mortality of elderly populations. Moreover, sarcopenia was also associated with higher level of albuminuria, risk of depression, and several metabolic diseases. Conclusions and Implications Sarcopenia significantly affected a wide range of adverse health‐related outcomes, particularly in patients of tumor and elderly populations. Because evidences of most outcomes were rated as “low” and “very low,” more prospective cohort studies are required in the future.
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- 2020
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5. Allium vegetable consumption and health: An umbrella review of meta‐analyses of multiple health outcomes
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Qianyi Wan, Ni Li, Liang Du, Rui Zhao, Mengshi Yi, Qiushi Xu, and Yong Zhou
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allium vegetables ,garlic ,health‐related outcomes ,onion ,umbrella review ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Abstract Previously, our meta‐analysis and other studies have suggested that allium vegetable consumption is beneficial for health, but no umbrella review has been conducted to assess the evidence of the various health benefits of allium vegetable consumption. Therefore, we conducted this umbrella review on this topic. This umbrella review included a total of 16 meta‐analyses with 50 unique outcomes. The most beneficial cancer‐related outcome was shown for gastric cancer (risk ratio 0.78; 95% confidence interval [CI] 0.67–0.91). In addition, only 8 weeks of garlic consumption significantly decreased serum total cholesterol (weighted mean differences −17.20 mg/dl; 95% CI −23.10 to −11.30), and patients with dyslipidemia who consumed garlic experienced more benefits than the whole population. Diabetic patients with longer durations of garlic intake experienced more benefits in terms of fasting blood glucose (FBG), HbA1c, and serum fructosamine than healthy participants, and garlic intake was associated with blood pressure reduction in hypertensive patients but not in normotensive participants. Limited side effects of garlic, such as garlic odor and gastrointestinal complaints, were reported among the included meta‐analyses. Our results suggested that allium vegetables might be beneficial for cancer prevention. In particular, garlic was comparatively safe and is recommended as a long‐term dietary component for patients with dyslipidemia, diabetes, and hypertension.
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- 2019
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6. Allium vegetable consumption and health: An umbrella review of meta‐analyses of multiple health outcomes
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Yong Zhou, Rui Zhao, Ni Li, Mengshi Yi, Liang Du, Qianyi Wan, and Qiushi Xu
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0301 basic medicine ,medicine.medical_specialty ,Population ,Reviews ,health‐related outcomes ,lcsh:TX341-641 ,Review ,allium vegetables ,03 medical and health sciences ,garlic ,0302 clinical medicine ,Internal medicine ,Diabetes mellitus ,medicine ,education ,onion ,education.field_of_study ,030109 nutrition & dietetics ,Cancer prevention ,biology ,umbrella review ,business.industry ,food and beverages ,biology.organism_classification ,medicine.disease ,Confidence interval ,Blood pressure ,Relative risk ,Allium ,030211 gastroenterology & hepatology ,business ,lcsh:Nutrition. Foods and food supply ,Dyslipidemia ,Food Science - Abstract
Previously, our meta‐analysis and other studies have suggested that allium vegetable consumption is beneficial for health, but no umbrella review has been conducted to assess the evidence of the various health benefits of allium vegetable consumption. Therefore, we conducted this umbrella review on this topic. This umbrella review included a total of 16 meta‐analyses with 50 unique outcomes. The most beneficial cancer‐related outcome was shown for gastric cancer (risk ratio 0.78; 95% confidence interval [CI] 0.67–0.91). In addition, only 8 weeks of garlic consumption significantly decreased serum total cholesterol (weighted mean differences −17.20 mg/dl; 95% CI −23.10 to −11.30), and patients with dyslipidemia who consumed garlic experienced more benefits than the whole population. Diabetic patients with longer durations of garlic intake experienced more benefits in terms of fasting blood glucose (FBG), HbA1c, and serum fructosamine than healthy participants, and garlic intake was associated with blood pressure reduction in hypertensive patients but not in normotensive participants. Limited side effects of garlic, such as garlic odor and gastrointestinal complaints, were reported among the included meta‐analyses. Our results suggested that allium vegetables might be beneficial for cancer prevention. In particular, garlic was comparatively safe and is recommended as a long‐term dietary component for patients with dyslipidemia, diabetes, and hypertension.
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- 2019
7. Soy and Isoflavone Consumption and Multiple Health Outcomes: Umbrella Review of Systematic Reviews and Meta‐Analyses of Observational Studies and Randomized Trials in Humans
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Mengshi Yi, Yi Chen, Rui Zhao, Wen Zhuang, Liang Du, Ni Li, Qianyi Wan, Lin Xia, Xiao-Ting Wu, and Yong Zhou
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Male ,0301 basic medicine ,medicine.medical_specialty ,Disease ,Health outcomes ,law.invention ,03 medical and health sciences ,Randomized controlled trial ,law ,Neoplasms ,Internal medicine ,Humans ,Medicine ,Randomized Controlled Trials as Topic ,Consumption (economics) ,030109 nutrition & dietetics ,business.industry ,Healthy diet ,Isoflavones ,Observational Studies as Topic ,030104 developmental biology ,Systematic review ,Cardiovascular Diseases ,Meta-analysis ,Female ,Observational study ,Soybeans ,business ,Food Science ,Biotechnology - Abstract
Scope To assess the existing evidence of associations between consumption of soy and isoflavone and multiple health outcomes. Methods and results This is an umbrella review of meta-analyses and systematic reviews of randomized trials and observational studies in humans. 114 Meta-analyses and systematic reviews are identified with 43 unique outcomes. Soy and isoflavone consumption seems more beneficial than harmful for a series of health outcomes. Beneficial associations are identified for cancers, cardiovascular disease, gynecological, metabolic, musculoskeletal, endocrine, neurological, and renal outcomes, particularly in perimenopausal women. Harmful association is only found for gastric cancer (RR: 1.17, 95% CI: 1.02-1.36) for high intake of miso soup (1-5 cups per day) in male. Conclusion Generally, soy and isoflavone consumption is more beneficial than harmful. The results herein support promoting soy intake as part of a healthy diet. Randomized controlled trials are necessary to confirm this finding.
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- 2019
8. Impact of Nonoptimal Intakes of Saturated, Polyunsaturated, and Trans Fat on Global Burdens of Coronary Heart Disease
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Qianyi Wang, Ashkan Afshin, Mohammad Yawar Yakoob, Gitanjali M. Singh, Colin D. Rehm, Shahab Khatibzadeh, Renata Micha, Peilin Shi, and Dariush Mozaffarian
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cardiovascular disease ,coronary heart disease ,dietary fat ,ω‐6 polyunsaturated fat ,saturated fat ,trans fat ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BackgroundSaturated fat (SFA), ω‐6 (n‐6) polyunsaturated fat (PUFA), and trans fat (TFA) influence risk of coronary heart disease (CHD), but attributable CHD mortalities by country, age, sex, and time are unclear. Methods and ResultsNational intakes of SFA, n‐6 PUFA, and TFA were estimated using a Bayesian hierarchical model based on country‐specific dietary surveys; food availability data; and, for TFA, industry reports on fats/oils and packaged foods. Etiologic effects of dietary fats on CHD mortality were derived from meta‐analyses of prospective cohorts and CHD mortality rates from the 2010 Global Burden of Diseases study. Absolute and proportional attributable CHD mortality were computed using a comparative risk assessment framework. In 2010, nonoptimal intakes of n‐6 PUFA, SFA, and TFA were estimated to result in 711 800 (95% uncertainty interval [UI] 680 700–745 000), 250 900 (95% UI 236 900–265 800), and 537 200 (95% UI 517 600–557 000) CHD deaths per year worldwide, accounting for 10.3% (95% UI 9.9%–10.6%), 3.6%, (95% UI 3.5%–3.6%) and 7.7% (95% UI 7.6%–7.9%) of global CHD mortality. Tropical oil–consuming countries were estimated to have the highest proportional n‐6 PUFA– and SFA‐attributable CHD mortality, whereas Egypt, Pakistan, and Canada were estimated to have the highest proportional TFA‐attributable CHD mortality. From 1990 to 2010 globally, the estimated proportional CHD mortality decreased by 9% for insufficient n‐6 PUFA and by 21% for higher SFA, whereas it increased by 4% for higher TFA, with the latter driven by increases in low‐ and middle‐income countries. ConclusionsNonoptimal intakes of n‐6 PUFA, TFA, and SFA each contribute to significant estimated CHD mortality, with important heterogeneity across countries that informs nation‐specific clinical, public health, and policy priorities.
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- 2016
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9. Weight-Based Clustering Decision Fusion Algorithm for Distributed Target Detection in Wireless Sensor Networks
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Haiping Huang, Lei Chen, Xiao Cao, Ruchuan Wang, and Qianyi Wang
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Electronic computers. Computer science ,QA75.5-76.95 - Abstract
We use a great deal of wireless sensor nodes to detect target signal that is more accurate than the traditional single radar detection method. Each local sensor detects the target signal in the region of interests and collects relevant data, and then it sends the respective data to the data fusion center (DFC) for aggregation processing and judgment making whether the target signal exists or not. However, the current judgment fusion rules such as Counting Rule (CR) and Clustering-Counting Rule (C-CR) have the characteristics on high energy consumption and low detection precision. Consequently, this paper proposes a novel Weight-based Clustering Decision Fusion Algorithm (W-CDFA) to detect target signal in wireless sensor network. It first introduces the clustering method based on tree structure to establish the precursor-successor relationships among the clusters in the region of interests and then fuses the decision data along the direction from the precursor clusters to the successor clusters gradually, and DFC (i.e., tree root) makes final determination by overall judgment values from subclusters and ordinary nodes. Simulation experiments show that the fusion rule can obtain more satisfactory system level performance at the environment of low signal to noise compared with CR and C-CR methods.
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- 2013
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