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22 results on '"Paterson, Michael"'

2. Longitudinal changes in subgingival biofilm composition following periodontal treatment

Author

Johnston, William, primary, Rosier, Bob T., additional, Carda‐Diéguez, Miguel, additional, Paterson, Michael, additional, Watson, Paddy, additional, Piela, Krystyna, additional, Goulding, Marilyn, additional, Ramage, Gordon, additional, Baranyia, Divyashri, additional, Chen, Tsute, additional, Al‐Hebshi, Nezar, additional, Mira, Alex, additional, and Culshaw, Shauna, additional

Published
2023
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6. The systemic inflammatory response following hand instrumentation versus ultrasonic instrumentation—a randomized controlled trial

Author

Johnston, William, Paterson, Michael, Piela, Krystyna M., Davison, Emily, Simpson, Annabel, Goulding, Marilyn, Ramage, Gordon, Sherriff, Andrea, and Culshaw, Shauna

Abstract

Objective:\ud \ud This study sought to investigate whether the immediate systemic inflammatory response following full mouth debridement differs following use of hand compared with ultrasonic instruments.\ud \ud Methods:\ud \ud Thirty‐nine periodontitis patients were randomised to treatment with full‐mouth debridement using either hand or ultrasonic instrumentation completed within 24 hours. Serum and periodontal clinical parameters were collected at baseline, day 1, day 7 and day 90 post‐treatment. Differences in systemic inflammatory markers were assessed using general linear models at each time‐point, corrected for age, gender, smoking status, body mass index and baseline levels of each marker.\ud \ud Results:\ud \ud Across all patients, serum C‐reactive protein increased at day 1, with no differences between hand and ultrasonic groups (p(adjusted)=0.22). There was no difference between groups in interleukin‐6 (p(adjusted)=0.29) or tumour necrosis factor α (p(adjusted)=0.53) at day 1. Inflammatory markers returned to baseline levels by day 7. Treatment resulted in equal and marked improvements in clinical parameters in both groups; however, total treatment time was on average shorter for ultrasonic instruments (p(adjusted)=0.002).\ud \ud Conclusions:\ud \ud Ultrasonic instrumentation resulted in shorter treatment time with comparable clinical outcomes. Levels of serum C‐reactive protein at day 1 were similar following debridement with hand or ultrasonic instruments.

Published
2020

7. Trends in the Prevalence and Incidence of Psoriasis and Psoriatic Arthritis in Ontario, Canada: A Population‐Based Study

Author

Eder, Lihi, primary, Widdifield, Jessica, additional, Rosen, Cheryl F., additional, Cook, Richard, additional, Lee, Ker‐Ai, additional, Alhusayen, Raed, additional, Paterson, Michael J., additional, Cheng, Stephanie Y., additional, Jabbari, Shirin, additional, Campbell, Willemina, additional, Bernatsky, Sasha, additional, Gladman, Dafna D., additional, and Tu, Karen, additional

Published
2019
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17. Crystal, Molecular and Electronic Structure of N,N′‐Diphenyl‐N,N′‐bis(2,4‐dimethylphenyl)‐(1,1′‐biphenyl)‐4,4′‐diamine and the Corresponding Radical Cation

Author

Low, Paul J., primary, Paterson, Michael A. J., additional, Puschmann, Horst, additional, Goeta, Andrés E., additional, Howard, Judith A. K., additional, Lambert, Christoph, additional, Cherryman, Julian C., additional, Tackley, Daniel R., additional, Leeming, Stephen, additional, and Brown, Bev, additional

Published
2003
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22. Identification of incident pancreatic cancer in Ontario administrative health data: A validation study.

Author

Wu JW, Azoulay L, Huang A, Paterson M, Wu F, Secrest MH, and Filion KB

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Female, Humans, Incidence, Male, Middle Aged, Ontario epidemiology, Pancreatic Neoplasms etiology, Reproducibility of Results, Young Adult, Algorithms, Databases, Factual, Pancreatic Neoplasms epidemiology
Abstract

Purpose: To validate three approaches for identifying incident cases of pancreatic cancer in Ontario administrative claims data., Methods: We created a cohort using Ontario (Canada) administrative health data from 2002 to 2012 and identified cases of pancreatic cancer with three approaches, using the Ontario Cancer Registry (OCR) as the reference standard. In the any diagnosis approach, cases were defined by primary or secondary diagnostic codes for pancreatic cancer in outpatient or inpatient records. In the any inpatient diagnosis approach, cases were defined using only diagnoses in hospital discharge abstracts. In the algorithm approach, cases were identified by an algorithm that combined the first two approaches. Comparing each approach to the OCR, we calculated the expected value and 95% confidence interval (CI) of the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). We also compared the event dates using each approach with those recorded in the OCR., Results: Among a total of 12 060 837 patients in Ontario administrative health data sources, 13 999 incident pancreatic cancer cases were identified in the OCR. Sensitivity ranged from 72.5% (algorithm) to 97.5% (any diagnosis), and PPV ranged from 38.4% (any diagnosis) to 78.9% (any inpatient diagnosis). Specificity and NPV were ~100% for all approaches. The median absolute difference in cancer event date ranged 0 to 15 days. The any inpatient diagnosis method had the highest PPV (78.9%; 95% CI: 78.2-79.5%) and moderate sensitivity (86.6%; 95% CI: 86.0-87.2%)., Conclusion: Inpatient diagnoses of pancreatic cancer in Ontario administrative heath data are suitable for pancreatic cancer case identification., (© 2018 John Wiley & Sons, Ltd.)

Published
2020
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