1. Lymphoid Cell Surface Markers in Acute Lymphocytic Leukaemia
- Author
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A. Astaldi, Mori Pg, G. C. B. Astaldi, M. Pasino, Massimo L, B. Bernardi, C. Rosanda-Vadala, A. Comelli, G. P. Tonini, P. Perutelli, and A. Giovanelli
- Subjects
Pathology ,medicine.medical_specialty ,Rosette Formation ,T-Lymphocytes ,Cell ,Receptors, Antigen, B-Cell ,Antineoplastic Agents ,Lymphocyte Activation ,Cell size ,Humans ,Medicine ,Acute lymphocytic leukaemia ,Lymphocytes ,Child ,Phytohaemagglutinin ,B-Lymphocytes ,Cluster of differentiation ,biology ,business.industry ,Cell Membrane ,Infant ,Hematology ,Prognosis ,Peripheral blood ,Leukemia, Lymphoid ,medicine.anatomical_structure ,Child, Preschool ,Immunology ,biology.protein ,business ,Lymphocyte markers - Abstract
Peripheral blood lymphoid cells of 29 patients with acute lymphocytic leukaemia (ALL) at onset were studied for characterization of B and T membrane markers and phytohaemagglutinin responsiveness. 24 cases (83%) were classified as "null" cell ALL and 5 (17%) as T-cell ALL. No relationship could be found between cytological presentation and immunological classification. Moreover, no correlation has been demonstrated between clinical-immunological parameters and prognosis, indicating that in our series of patients, assessment of cell size and surface markers were not a reliable predictor of prognosis.
- Published
- 2009
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