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5 results on '"Milne, ME"'

1. Case series: Computed tomography (CT) demonstrates lacrimal canal involvement in koalas (Phascolarctos cinereus) with maxillary incisor dental disease.

Author

Bryce, AJ, Milne, ME, Tyrrell, D, Bodley, K, Bryce, AJ, Milne, ME, Tyrrell, D, and Bodley, K

Abstract

Dental disease is common in wild and captive koalas. Effective treatments are limited and dental disease may not be recognised until it is quite severe. We describe the appearance of varying severities of dental disease on computed tomography (CT) images in a case series of six koalas. This case series demonstrates the use of CT to detect both mild and severe dental disease in koalas. The study also documents the normal CT appearance of the nasolacrimal duct in the koala. The only clinical abnormality in koalas with the mildest dental disease was ocular discharge. Computed tomography findings associated with ocular discharge were periapical lysis of first maxillary incisors, lacrimal canal remodelling and subsequent nasolacrimal duct obstruction. Dental disease should be a differential diagnosis for ocular discharge in koalas and CT examination enables visualisation of early stages of dental disease.

Published
2022

5. Outbreak of equine herpesvirus type 1 myeloencephalitis: new insights from virus identification by PCR and the application of an EHV-1-specific antibody detection ELISA.

Author

Studdert MJ, Hartley CA, Dynon K, Sandy JR, Slocombe RF, Charles JA, Milne ME, Clarke AF, and El-Hage C

Subjects
Abortion, Veterinary epidemiology, Animals, Animals, Newborn, Antibodies, Viral blood, Ataxia etiology, Ataxia veterinary, Encephalomyelitis complications, Encephalomyelitis epidemiology, Enzyme-Linked Immunosorbent Assay veterinary, Female, Herpesviridae Infections complications, Herpesviridae Infections epidemiology, Herpesvirus 1, Equid genetics, Herpesvirus 1, Equid isolation & purification, Horse Diseases blood, Horse Diseases virology, Horses, Immunohistochemistry veterinary, Male, Polymerase Chain Reaction veterinary, Pregnancy, Pregnancy Complications, Infectious epidemiology, Victoria epidemiology, Antibodies, Viral analysis, Disease Outbreaks veterinary, Encephalomyelitis veterinary, Herpesviridae Infections veterinary, Herpesvirus 1, Equid immunology, Horse Diseases epidemiology, Pregnancy Complications, Infectious veterinary
Abstract

Five of 10 pregnant, lactating mares, each with a foal at foot, developed neurological disease. Three of them became recumbent, developed complications and were euthanased; of the two that survived, one aborted an equine herpesvirus type 1 (EHV-1)-positive fetus 68 days after the first signs were observed in the index case and the other gave birth to a healthy foal on day 283 but remained ataxic and incontinent. The diagnosis of EHV-1 myeloencephalitis was supported by postmortem findings, PCR identification of the virus and by serological tests with an EHV-1-specific ELISA. At the time of the index case, the 10 foals all had a heavy mucopurulent nasal discharge, and PCR and the ELISA were used to detect and monitor EHV-1 infection in them. The status of EHV-1 infection in the five in-contact mares was similarly monitored. Sera from three of the affected mares, taken seven days after the index case were negative or had borderline EHV-1-specific antibody titres. In later serum samples there was an increase in the titres of EHV-1-specific antibody in two of the affected mares. In contrast, sera from the five unaffected in-contact mares were all EHV-1-antibody positive when they were first tested seven or 13 days after the index case.

Published
2003
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