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Rhodium-catalyzed ortho-C-H functionalization is well known in the literature. Described herein is the Xphos-supported rhodium catalysis of meta-C-H olefination of benzylsulfonic acid and phenyl acetic acid frameworks with the assistance of a para-methoxy-substituted cyano phenol as the directing group. Complete mono-selectivity is observed for both scaffolds. A wide range of olefins and functional groups attached to arene are tolerated in this protocol.

A facile and efficient method for the construction of 3-alkyl/aryl substituted 1,4-benzoxazine and benzoxazepine via AgNO3 catalyzed cyclization of propargyloxy sulfonamides and their anti-tubercular activity against Mycobacterium tuberculosis H37RV is described. This cyclization proceeds through 6-exo-dig manner to generate the products in moderate to good yields.

Divinylbenzene derivatives represent an important class of molecular building blocks in organic chemistry and materials science. Reported herein is the palladium-catalyzed synthesis of divinylbenzenes by meta-C-H olefination of sulfone-based arenes. Successful sequential olefinations in a position-selective manner provided a novel route for the synthesis of hetero-dialkenylated products, which are difficult to access using conventional methods. Additionally, 1,3,5-trialkenylated compounds can be generated upon successful removal of the directing group.

New bicyclic pyridine-phosphane ligands were prepared, and their iridium complexes were evaluated in asymmetric hydrogenation of trisubstituted olefins with non-coordinating and weakly coordinating ...

Using an o-cyanophenoxy group as directing group benzylsulfonic acid esters are olefinated in meta-position by terminal and internal olefins.

Phenylacetic acids (I) and (V) having a 2-hydroxybenzonitrile substituent as directing group undergo meta-selective olefination with acrylates and vinyl ketones.

New bicyclic pyridine-phosphane ligands were prepared, and their iridium complexes were evaluated in asymmetric hydrogenation of trisubstituted olefins with non-coordinating and weakly coordinating ...

It is found that [Ag(cod)2]PF6 as well as [Ag(nbd)2]PF6 and [Ag(cyclohexadiene)2]PF6 efficiently promote the C-arylation of arylated N-tosylaziridines giving β-diaryl amines with excellent regioselectivity.

[Ag(COD)2]PF6 catalyzes the reaction between propargyl alcohols and N-tosylaziridines/azetidines leading to a diverse range of N,O-heterocycles, namely, oxazines, oxazepines, and oxazocines via ring-opening and ring-closing in a cascade

N-Tosyl aziridines react with a variety of arenes and heteroarenes in the presence of 1–2% of silver hexafluorophosphate at room temperature to afford the corresponding β-aryl amine derivatives in excellent yields and with high regioselectivity.