1. Diabetic ketoacidosis drives <scp>COVID‐19</scp> related hospitalizations in children with type <scp>1</scp> diabetes
- Author
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Kathryn M. Sumpter, Sadana Balachandar, Janine Sanchez, Robert Rapaport, Anastasia Albanese-O'Neill, Catherina T. Pinnaro, Srinath Sanda, Alissa J. Roberts, Jenise C. Wong, Saketh Rompicherla, Shideh Majidi, Mary Pat Gallagher, Mariam Gangat, Osagie Ebekozien, Abha Choudhary, Tossaporn Seeherunvong, Brynn E. Marks, Ana L. Creo, Liana Gabriel, Meredith Wilkes, Guy T. Alonso, Jamie R. Wood, Anna Cymbaluk, Sarah K. Lyons, Neha S. Patel, and Jose Jimenez-Vega
- Subjects
Male ,Glycated Hemoglobin A ,type 1 diabetes ,Cross-sectional study ,Endocrinology, Diabetes and Metabolism ,030204 cardiovascular system & hematology ,0302 clinical medicine ,Risk Factors ,1型糖尿病 ,DKA ,Registries ,Child ,Pediatric ,Diabetes ,Age Factors ,Up-Regulation ,新型冠状病毒肺炎 ,Hospitalization ,Exact test ,儿科 ,Child, Preschool ,Disease Progression ,Public Health and Health Services ,Original Article ,Female ,Type 1 ,Insulin pump ,medicine.medical_specialty ,Adolescent ,Diabetic ketoacidosis ,Clinical Sciences ,030209 endocrinology & metabolism ,Risk Assessment ,Diabetic Ketoacidosis ,03 medical and health sciences ,COVID‐19 ,Internal medicine ,Diabetes mellitus ,Diabetes Mellitus ,medicine ,Humans ,Risk factor ,Preschool ,Metabolic and endocrine ,Glycated Hemoglobin ,Type 1 diabetes ,business.industry ,Prevention ,Infant, Newborn ,Infant ,COVID-19 ,Original Articles ,Odds ratio ,Newborn ,medicine.disease ,United States ,pediatric ,Diabetes Mellitus, Type 1 ,Cross-Sectional Studies ,business ,Biomarkers - Abstract
Background Diabetes is a risk factor for poor COVID‐19 outcomes, but pediatric patients with type 1 diabetes are poorly represented in current studies. Methods T1D Exchange coordinated a US type 1 diabetes COVID‐19 registry. Forty‐six diabetes centers submitted pediatric cases for patients with laboratory confirmed COVID‐19. Associations between clinical factors and hospitalization were tested with Fisher's Exact Test. Logistic regression was used to calculate odds ratios for hospitalization. Results Data from 266 patients with previously established type 1 diabetes aged, Highlights Outcomes for children with type 1 diabetes who experience COVID‐19 are currently unknown. We report 266 cases from US diabetes clinics of children with type 1 diabetes who had COVID‐19. Diabetic ketoacidosis was the major adverse outcome, and it was associated with higher A1c.
- Published
- 2021
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