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Your search keyword '"Masera, N"' showing total 4 results
Start Over Author "Masera, N" Publisher wiley
4 results on '"Masera, N"'

1. Acute chest syndrome in children with sickle cell disease: Data from a national AIEOP cohort identify priority areas of intervention in a hub‐and‐spoke system

Author

Munaretto, V., primary, Corti, P., additional, Bertoni, E., additional, Tripodi, S. I., additional, Guerzoni, M. E., additional, Cesaro, S., additional, Arcioni, F., additional, Piccolo, C., additional, Mina, T., additional, Zecca, M., additional, Cuzzubbo, D., additional, Casale, M., additional, Palazzi, G., additional, Notarangelo, L. D., additional, Masera, N., additional, Samperi, P., additional, Perrotta, S., additional, Russo, G., additional, Sainati, L., additional, and Colombatti, R., additional

Published
2023
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2. Development of RBC transfusion indications and the collection of patient-specific pre-transfusion information

Author

Yazer, M. H., primary, van de Watering, L., additional, Lozano, M., additional, Sirdesai, S., additional, Rushford, K., additional, Wood, E. M., additional, Yokoyama, A. P., additional, Kutner, J. M., additional, Lin, Y., additional, Callum, J., additional, Cserti-Gazdewich, C., additional, Lieberman, L., additional, Pendergrast, J., additional, Pendry, K., additional, Murphy, M. F., additional, Selleng, K., additional, Greinacher, A., additional, Marwaha, N., additional, Sharma, R., additional, Jain, A., additional, Orlin, Y., additional, Yahalom, V., additional, Perseghin, P., additional, Incontri, A., additional, Masera, N., additional, Okazaki, H., additional, Ikeda, T., additional, Nagura, Y., additional, Zwaginga, J. J., additional, Pogłod, R., additional, Rosiek, A., additional, Letowska, M., additional, Yuen, J., additional, Cid, J., additional, Harm, S. K., additional, and Adhikari, P., additional

Published
2017
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3. Transfusion service management of sickle-cell disease patients

Author

Yazer, M.H., primary, Lozano, M., additional, Crighton, G., additional, Greenway, A., additional, Comande, M., additional, Savoia, H., additional, Wood, E., additional, Gilli, S., additional, Castilho, L., additional, Saad, Sara T.O., additional, Galactéros, F., additional, Noizat-Pirenne, F., additional, Pazgal, I., additional, Stark, P., additional, Orlin, Y., additional, Perseghin, P., additional, Masera, N., additional, Cela, E., additional, Anguita, J., additional, Wikman, A., additional, and Delaney, M., additional

Published
2015
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4. Hydroxyurea prescription, availability and use for children with sickle cell disease in Italy: Results of a National Multicenter survey

Author

Nicoletta Masera, Laura Sainati, Gian Luca Forni, Angelica Barone, Silverio Perrotta, Piera Samperi, Elena Facchini, Paola Corti, Maddalena Casale, Raffaella Colombatti, Maria Elena Guerzoni, Paolo Rigano, Simone Cesaro, Elisa Bonetti, Maurizio Miano, Giovanni Palazzi, Lucia Dora Notarangelo, Giovanna Russo, Giovanni Carlo Del Vecchio, Federica Menzato, Colombatti, R, Palazzi, G, Masera, N, Notarangelo, Ld, Bonetti, E, Samperi, P, Barone, A, Perrotta, Silverio, Facchini, E, Miano, M, Del Vecchio, Gc, Guerzoni, Me, Corti, P, Menzato, F, Cesaro, S, Casale, Maddalena, Rigano, P, Forni, Gl, Russo, G, and Sainati, L.

Subjects
children, hydroxyurea, Italy, sickle cell disease, usage, Adolescent, Anemia, Sickle Cell, Child, Child, Preschool, Emigrants and Immigrants, Female, Follow-Up Studies, Humans, Hydroxyurea, Infant, Male, Drug Prescriptions, Health Services Accessibility, Pediatrics, medicine.medical_specialty, Anemia, Population, Pediatrics, Perinatology and Child Health, Hematology, Oncology, Disease, 03 medical and health sciences, 0302 clinical medicine, medicine, Medical prescription, Preschool, education, education.field_of_study, business.industry, Retrospective cohort study, Perinatology and Child Health, medicine.disease, Acute chest syndrome, Sickle Cell, Regimen, 030220 oncology & carcinogenesis, business, 030215 immunology, Cohort study
Abstract

Background The number of patients with sickle cell disease (SCD) has increased in Italy in the past decade due to immigration. In spite of the established efficacy of hydroxyurea (HU) in childhood, population-based data regarding its prescription and effectiveness come mainly from studies performed in adults or outside Europe. Population and methods The Hydroxyurea in SCD: A Large Nation-wide Cohort Study from Italy was a retrospective cohort study of adult and pediatric patients with SCD attending 32 centers. Pediatric data are analyzed separately. Results Out of 504 children followed in 11 centers, 206 (40%) were on HU (194 SS/Sβ°, 12 SC/Ss+); 74% came from Sub-Saharian Africa and 18% from Europe. HU therapy indications for SS/Sβ° patients were as follows: 57% painful vaso-occlusive crisis, acute chest syndrome or both, 24% anemia, 8% anemia, and other reasons (the majority had Hb ≤ 8–8.5 g/dl, revealing scarce acceptance of low Hb values by pediatric hematologist). Mean starting dose was 15.5 mg/kg, and dose at full regimen was 17.1 mg/kg. Mean age at HU therapy was 7.68 years, although it was lower for SS/Sβ° patients. Only 10% started HU before 3 years. In 92%, 500 mg capsule was used; in 6%, the galenic was used; and in 2%, 100 mg tablet was used. Significant reduction of clinical events and inpatients admissions, with improvement in hematological parameters, was observed for SS/Sβ° patients and a trend toward improvement for SC/Ss+ patients was also observed. Conclusions HU effectiveness is demonstrated in a national cohort of children with SCD living in Italy, even at a lower dose than recommended, revealing good adherence to a treatment program by a socially vulnerable group of patients such as immigrants.

Published
2017
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