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Based on two pretreatment evaluations, doubling time (DT) was calculated in 75 cases of invasive breast cancer (BC). The cases studied were more or less equally distributed between three DT groups: fast-growing tumors (DT less than 90 days), intermediate cases (DT between 90 and 180 days), and slow-growing tumors (DT greater than 180 days. A correlation was found to exist between DT and patient age and, to an even greater extent, between DT and pathologic prognostic indicators such as histologic grading and nuclear grade. Inflammatory symptoms were not associated with DT, but were closely related to the size of the tumor and regional lymph node involvement. The date of detection of distant metastases depended heavily on the DT of the BC:BC with shorter DT = earlier metastatic spread. The presence of inflammatory signs was also decisive: within each DT category, inflammatory BC metastases were both more frequent and precocious.

L'etude des proprietes rheologiques a l'etat fondu de materiaux composites a base de farines de bois ou de bois retifie et de polyethylene basse densite apolaire ou de copolymeres d'ethylene polaires, a ete effectuee a differentes vitesses de cisaillement. Le comportement des melanges varie avec le degre de torrefaction du bois et la nature polaire ou apolaire de la matrice. Une interpretation de ces differences de comportement, basees sur les interactions fibres-matrices, a ete proposee. Des mesures d'essais mecaniques, effectuees sur des eprouvettes composites, confirment les resultats presentes a l'etat fondu. // Investigation of the molten state properties of composite materials based on powdered pine or torrefied pines and low density polyethylene or ethylene copolymers is carried out at different shear rates. Mixtures with a polyethylene matrix exhibit a different behaviour compared to those based on copolymers. An interpretation of these differences based on fibre/matrix interactions is proposed. Mechanical tests carried out on composite test-bars corroborate the results obtained from the molten state.