1. Metabolic Correlates in Infants and Children During Anaesthesia and Surgery
- Author
-
S. G. E. LindahiM.D., M. G. Hulse, and D. J. Hatch
- Subjects
Male ,medicine.medical_specialty ,Carbon dioxide production ,Body weight ,Intraoperative Period ,chemistry.chemical_compound ,Oxygen Consumption ,Humans ,Medicine ,Child ,Monitoring, Physiologic ,Pulmonary Gas Exchange ,business.industry ,Halothane anaesthesia ,Body Weight ,Infant ,General Medicine ,Controlled ventilation ,Surgery ,Respiratory quotient ,Anesthesiology and Pain Medicine ,chemistry ,Child, Preschool ,Surgical Procedures, Operative ,Anesthesia ,Carbon dioxide ,Breathing ,Ventilation volume ,Female ,Anesthesia, Inhalation ,Halothane ,business ,human activities ,circulatory and respiratory physiology - Abstract
In 58 infants and children with body weights between 2.8 and 20.5 kg carbon dioxide production (VCO2 ml min-1) was measured during halothane anaesthesia for minor surgical procedures. In 22 cases measurements were made during both spontaneous and controlled ventilation during the same operation. A non-rebreathing circuit was used. Expired ventilation volume was measured with a dry gas meter and expired gas collected during 3-5 min in a Douglas bag. The carbon dioxide fraction of exhaled gas was determined with a sampling Gould capnograph. A respiratory quotient (RQ) of 0.8 was used to calculate oxygen consumption (VO2 ml min-1). During spontaneous breathing, regression analysis of the relationship between VCO2 and kg and between VO2 and kg showed high intercepts while corresponding relations to kg3/4 revealed an almost direct proportionality. Thus, VCO2 and VO2 ought to be related to body weight in kg3/4 in spontaneously breathing children. The mean value (+/- 1 s.d.) for VCO2 was 11.4 +/- 3.1 ml kg-3/4 and for VO2 14.2 +/- 3.9 ml kg-3/4. During controlled ventilation, the relationship between kg b.w. showed for VCO2 as well as for VO2 an almost direct proportionality with a mean value (+/- 1 s.d.) for VCO2 of 6.3 +/- 1.6 ml min-1 kg-1 and for VO2 of 7.8 +/- 2.0 ml min-1 kg-1. Prediction of VO2 for infants and children of this size could be based upon 14 X kg3/4 during halothane anaesthesia and surgery.
- Published
- 1984