1. Hypersensitivity reactions to vaccines in children: from measles to SARS‐CoV‐2
- Author
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Carlo Caffarelli, Lucia Liotti, Annamaria Bianchi, Paolo Bottau, Silvia Caimmi, Giuseppe Crisafulli, Fabrizio Franceschini, Claudia Paglialunga, Francesca Saretta, and Francesca Mori
- Subjects
Vaccines ,COVID-19 Vaccines ,SARS-CoV-2 ,Vaccination ,Immunology ,Pediatrics, Perinatology and Child Health ,Hypersensitivity ,COVID-19 ,Humans ,Immunology and Allergy ,Child ,Measles - Abstract
Allergic individuals at risk for hypersensitivity reactions to measles vaccine marketed for a long time are well established. On the other hand, risk factors for hypersensitivity reactions to the new mRNA COVID-19 vaccines currently include a history of allergy, allergy to excipient of the vaccine, or hypersensitivity reactions to the first dose of COVID-19 vaccine. In the last two cases, the recipient should be assessed by an allergist before vaccination to share a decision on the choice of vaccination. Studies on skin testing accuracy and desensitization protocols to the COVID-19 vaccines and the efficacy of potential alternatives in patients with confirmed hypersensitivity reactions to the first COVID-19 vaccine are necessary to improve the safety of COVID-19 vaccines.
- Published
- 2022