Search

Your search keyword '"Liu, Zhongjun"' showing total 23 results
Start Over Author "Liu, Zhongjun" Publisher wiley
23 results on '"Liu, Zhongjun"'

6. Evaluation of a new spinal surgical robotic system of Kirschner wire placement for lumbar fusion: A multi‐centre, randomised controlled clinical study

Author

Li, Junyu, primary, Huang, Lin, additional, Zhou, Wenyu, additional, Wang, Zizhen, additional, Li, Zongze, additional, Zeng, Lin, additional, Liu, Zhongjun, additional, Shen, Huiyong, additional, Cai, Zhaopeng, additional, Gu, Hongsheng, additional, Yang, Xinjian, additional, Zhang, Rui, additional, Hu, Wanheng, additional, Yu, Miao, additional, and Chen, Jianting, additional

Published
2020
Full Text
View/download PDF

14. Autophagy and Apoptosis Cross Talk: Cross Talk Between Autophagy and Apoptosis Contributes to ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death (Adv. Healthcare Mater. 17/2018)

Author

He, Guanping, primary, Ma, Yunlong, additional, Zhu, Ye, additional, Yong, Lei, additional, Liu, Xiao, additional, Wang, Peng, additional, Liang, Chen, additional, Yang, Chenlong, additional, Zhao, Zhigang, additional, Hai, Bao, additional, Pan, Xiaoyu, additional, Liu, Zhongjun, additional, Liu, Xiaoguang, additional, and Mao, Chuanbin, additional

Published
2018
Full Text
View/download PDF

16. Cross Talk Between Autophagy and Apoptosis Contributes to ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death

Author

He, Guanping, primary, Ma, Yunlong, additional, Zhu, Ye, additional, Yong, Lei, additional, Liu, Xiao, additional, Wang, Peng, additional, Liang, Chen, additional, Yang, Chenlong, additional, Zhao, Zhigang, additional, Hai, Bao, additional, Pan, Xiaoyu, additional, Liu, Zhongjun, additional, Liu, Xiaoguang, additional, and Mao, Chuanbin, additional

Published
2018
Full Text
View/download PDF

22. Evaluation of a new spinal surgical robotic system of Kirschner wire placement for lumbar fusion: A multi-centre, randomised controlled clinical study.

Author

Li J, Huang L, Zhou W, Wang Z, Li Z, Zeng L, Liu Z, Shen H, Cai Z, Gu H, Yang X, Zhang R, Hu W, Yu M, and Chen J

Subjects
Bone Wires, Humans, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae surgery, Pedicle Screws, Robotic Surgical Procedures, Spinal Fusion
Abstract

Background: To introduce a novel robotic system 'Orthbot' that has been developed and tested as a surgical assistant for auto-placement of the K-wire in lumbar fusion., Methods: This is a multi-centre, randomized controlled clinical study that includes 56 patients (robot group, RG: 27, free-hand group, FG: 29). Following the pre-operative planning and intra-operative fluoroscopic images, the 'Orthbot' automatically completed registration and K-wire placement under the supervision of the surgeon. Deviation distance (DD) and deviation angle (DA) were used as the primary parameters to evaluate the accuracy of the robotic system., Results: The average DD was 0.95 ± 0.377 mm and 4.35 ± 2.01 mm, respectively in the RG and FG (p < 0.001). The average DA of the K-wire in the coronal plane and the sagittal plane in X-Ray was respectively 6.80 ± 7.79° and 1.27 ± 2.32° in the RG (p < 0.001), and 22.22 ± 16.85° and 4.57 ± 3.86° in the FG (p < 0.001), which showed a higher accuracy rate in the robotic-assisted cases compared to the free-hand cases., Conclusions: The novel robotic system could achieve accurate K-wire insertions as indicated by the radiological results., (© 2020 John Wiley & Sons Ltd.)

Published
2021
Full Text
View/download PDF

23. Increased levels of hypoxia-inducible factor-1α are associated with Bcl-xL expression, tumor apoptosis, and clinical outcome in chondrosarcoma.

Author

Chen C, Zhou H, Wei F, Jiang L, Liu X, Liu Z, and Ma Q

Subjects
Adolescent, Adult, Aged, Bone Neoplasms chemistry, Cell Line, Tumor, Chondrosarcoma chemistry, Female, Humans, Hypoxia-Inducible Factor 1, alpha Subunit analysis, Male, Middle Aged, Apoptosis, Bone Neoplasms pathology, Chondrosarcoma pathology, Hypoxia-Inducible Factor 1, alpha Subunit physiology, bcl-X Protein analysis
Abstract

Hypoxia-inducible factor (HIF)-1α is a key nuclear transcription factor that regulates the cellular response to hypoxia, and is important for solid tumor growth and survival. However, the underlying role of HIF-1α in human chondrosarcoma has not been well characterized. This study aims to investigate the expression patterns of HIF-1α in chondrosarcoma, and its association with clinicopathologic features, Bcl-xL expression, apoptosis index (AI), and overall survival of patients with chondrosarcoma. Our results shown that the protein levels of HIF-1α were increased, and the mRNA and protein levels of Bcl-xL were also increased in SW1353 cells under hypoxic conditions. In eight patients with chondrosarcoma, increased expression of HIF-1α and Bcl-xL was detected in chondrosarcoma tissues compared with the paired adjacent normal tissues. Of 34 archival specimens of chondrosarcomas, 20 (58.8%) showed high HIF-1α protein expression as compared to benign cartilage tumors. Increased HIF-1α expression was correlated with a higher pathological grade and MSTS stage of chondrosarcoma. Moreover, HIF-1α expression was significantly associated with Bcl-xL expression and AI. More significantly, the survival rate of patients with HIF-1α high tumors was significantly lower than that of patients with HIF-1α low tumors. These findings suggest that increased HIF-1α levels mediated up-regulation of Bcl-xL play a prominent role in evasion of apoptosis and tumor progression, and can be predictive for the prognosis in human chondrosarcoma., (Copyright © 2010 Orthopaedic Research Society.)

Published
2011
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results