Search

Your search keyword '"Liu, Sijie"' showing total 29 results
Start Over Author "Liu, Sijie" Publisher wiley
29 results on '"Liu, Sijie"'

2. Targeting epidermal growth factor receptor signalling pathway: A promising therapeutic option for COVID‐19

Author

Razzaq, Aroona, primary, Disoma, Cyrollah, additional, Zhou, Yuzheng, additional, Tao, Siyi, additional, Chen, Zongpeng, additional, Liu, Sixu, additional, Zheng, Rong, additional, Zhang, Yongxing, additional, Liao, Yujie, additional, Chen, Xuan, additional, Liu, Sijie, additional, Dong, Zijun, additional, Xu, Liangtao, additional, Deng, Xu, additional, Li, Shanni, additional, and Xia, Zanxian, additional

Published
2023
Full Text
View/download PDF

5. Engineered Core–Shell Multifunctional Nano‐Tracer in Raman‐Silent Region with Highly Retained Affinity to Enhance Lateral Flow Immunoassays

Author

Liu, Sijie, primary, Luo, Xing, additional, Shu, Rui, additional, Liao, Yangjun, additional, Dou, Leina, additional, Bu, Tong, additional, Wang, Shaochi, additional, Li, Yuechun, additional, Sun, Jing, additional, Zhang, Daohong, additional, Zhu, Mingqiang, additional, and Wang, Jianlong, additional

Published
2022
Full Text
View/download PDF

14. A High-Temperature Order-Disorder Phase Transition Coupled With Conformational Change in the Hybrid Material [C6H13NH]2⋅ZnBr4

Author

Sangen Zhao, Muhammad Adnan Asghar, Lina Li, Zhihua Sun, Liu Sijie, Chengmin Ji, Aurang Zeb, Junhua Luo, and Tariq Khan

Subjects
Phase transition, Conformational change, Chemistry, Organic Chemistry, 02 engineering and technology, General Chemistry, Dielectric, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Biochemistry, Heat capacity, 0104 chemical sciences, Crystallography, Differential scanning calorimetry, Transition point, 0210 nano-technology, Hybrid material, Conformational isomerism
Abstract

A new high-temperature, hybrid, phase-transition material, 1-methylpiperidinium tetrabromozincate (1), that shows a reversible transition at 345 K was synthesized. Differential scanning calorimetry and specific heat capacity measurements confirmed this reversible transformation with a large heat hysteresis of 25 K, which describes a typical first-order phase transition in 1. The dielectric constant exhibited a steplike anomaly and showed high and low dielectric states in the high- and room-temperature phases, respectively, and therefore, this hybrid might be considered as a potential switchable dielectric material. The variable-temperature powder X-ray diffraction patterns displayed remarkable shifts between the experimental patterns at the two different phases. Single-crystal X-ray diffraction analyses at various temperatures revealed that the origin of this transformation could be attributed to disordering of the bromine atoms in the anion and the nitrogen atom of the cation. The cation also assumed a conformational change, which was likely induced by the disordered nitrogen atom. The conformational onset of the transformation of the cation from a planar conformer into a relaxed chair also occurred upon decreasing the temperature below transition point; thus, the combined order-disorder and conformational change induced the structural transformation and the change in symmetry.

Published
2016

20. Direct activation of tachykinin receptors within baroreflex afferent pathway and neurocontrol of blood pressure regulation

Author

Yuan, Mei, primary, Ma, Mei‐Na, additional, Wang, Ting‐Yu, additional, Feng, Yan, additional, Chen, Pei, additional, He, Chao, additional, Liu, Sijie, additional, Guo, Yun‐Xia, additional, Wang, Yue, additional, Fan, Yao, additional, Wang, Lu‐Qi, additional, E, Xiao‐Qiang, additional, Qiao, Guo‐Fen, additional, and Li, Bai‐Yan, additional

Published
2018
Full Text
View/download PDF

29. Targeting epidermal growth factor receptor signalling pathway: A promising therapeutic option for COVID-19.

Author

Razzaq A, Disoma C, Zhou Y, Tao S, Chen Z, Liu S, Zheng R, Zhang Y, Liao Y, Chen X, Liu S, Dong Z, Xu L, Deng X, Li S, and Xia Z

Subjects
Humans, Antiviral Agents therapeutic use, Antiviral Agents pharmacology, COVID-19 Drug Treatment, Erlotinib Hydrochloride therapeutic use, Post-Acute COVID-19 Syndrome, Pulmonary Fibrosis metabolism, SARS-CoV-2 metabolism, COVID-19, ErbB Receptors genetics, ErbB Receptors metabolism, Signal Transduction drug effects
Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously producing new variants, necessitating effective therapeutics. Patients are not only confronted by the immediate symptoms of infection but also by the long-term health issues linked to long COVID-19. Activation of epidermal growth factor receptor (EGFR) signalling during SARS-CoV-2 infection promotes virus propagation, mucus hyperproduction, and pulmonary fibrosis, and suppresses the host's antiviral response. Over the long term, EGFR activation in COVID-19, particularly in COVID-19-induced pulmonary fibrosis, may be linked to the development of lung cancer. In this review, we have summarised the significance of EGFR signalling in the context of SARS-CoV-2 infection. We also discussed the targeting of EGFR signalling as a promising strategy for COVID-19 treatment and highlighted erlotinib as a superior option among EGFR inhibitors. Erlotinib effectively blocks EGFR and AAK1, thereby preventing SARS-CoV-2 replication, reducing mucus hyperproduction, TNF-α expression, and enhancing the host's antiviral response. Nevertheless, to evaluate the antiviral efficacy of erlotinib, relevant clinical trials involving an appropriate patient population should be designed., (© 2023 The Authors. Reviews in Medical Virology published by John Wiley & Sons Ltd.)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results