23 results on '"Lauri S."'
Search Results
2. Transfusion policies in coronary artery bypass - a nationwide survey in Finland
- Author
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G. Myllylä, L. Kytölä, and Lauri S. Nuutinen
- Subjects
Adult ,medicine.medical_specialty ,Blood transfusion ,medicine.medical_treatment ,Humans ,Medicine ,Blood Transfusion ,Coronary Artery Bypass ,Elective surgery ,Prospective cohort study ,Intensive care medicine ,Finland ,Aged ,Retrospective Studies ,Aged, 80 and over ,business.industry ,Confounding ,Retrospective cohort study ,General Medicine ,Middle Aged ,Cardiac surgery ,Anesthesiology and Pain Medicine ,medicine.anatomical_structure ,Emergency medicine ,Fresh frozen plasma ,business ,Artery - Abstract
Background: Since the discovery of HIV, minimizing the use of donor blood has become increasingly important in surgical activity. In Finland, however, the use of homologous red blood has grown considerably during the past years. Therefore, we found it necessary to conduct a nationwide survey of transfusion practices in elective surgery. This report deals with transfusions in coronary artery bypass (CABG) operations in all Finnish cardiac centres. Methods: The study group comprised 804 primary CABG patients operated during a 2-year period. Two reviewers retrospectively examined the data concerning the use of and indications for homologous and autologous blood in the patient charts. Results: In all, 705 (88%) of patients received homologous blood. The proportions of patients receiving blood components differed between hospitals: from 53 to 99% for red cells, 2 to 22% for fresh frozen plasma and 5 to 49% for platelets. The variation was not caused by diverse patient populations: the mean number of blood component units transfused per patient differed from 1 to 6 between centres — even after adjustment for confounding variables. Multiple blood conservation methods were used in one centre. Nevertheless, homologous blood was administered to 88% of their patients. Conclusions: A considerable proportion of CABG patients are transfused with homologous blood in Finland compared to other countries. In addition, the transfusion practices proved highly variable between hospitals and were determined largely by local opinions. This study reveals a clear demand for prospective studies and constructive discussion among anaesthesiologists to establish uniform guidelines for blood use in cardiac surgery.
- Published
- 1998
3. Introducing epidural fentanyl for on-ward pain relief after major surgery
- Author
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Lauri S. Nuutinen, U. Havukainen, T. E. Salomäki, M. Turunen, and Hannu Kokki
- Subjects
Male ,medicine.medical_specialty ,Respiratory rate ,Nausea ,medicine.medical_treatment ,Epidural fentanyl ,Pain relief ,Fentanyl ,Rating scale ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Pain Measurement ,Pain, Postoperative ,Chemotherapy ,business.industry ,Respiration ,General Medicine ,Middle Aged ,Surgery ,Analgesia, Epidural ,Analgesics, Opioid ,Anesthesiology and Pain Medicine ,Anesthesia ,Female ,medicine.symptom ,business ,medicine.drug - Abstract
Background: Epidural opioids have been recommended for analgesia after major surgery. In this report we describe how we introduced a low-cost, on-ward, nurse-based acute pain service using epidural fentanyl after major surgery in the University Hospitals of Oulu and Kuopio. Methods: In order to evaluate the feasibility of epidural fentanyl infusion administered by ward nurses, we prospectively assessed pain and side effects during fentanyl infusion (median duration 41 h) after major surgery in 305 consecutive patients in Kuopio. Results: 92% of the patients on the ward who had received epidural fentanyl infusion at 31–54 μg h-1 reported at most three episodes of severe pain (/ Numerical Rating Scale > 3/10) during the initial postoperative days, but there were some patients (8%) who reported several episodes (>3) of more severe pain (Numerical Rating Scale > 3). Three patients (0.9%) showed a diminished respiratory rate (
- Published
- 1996
4. Management of upper airway obstruction using a Seldinger minitracheotomy kit
- Author
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Tero Ala-Kokko, M Kyllönen, and Lauri S. Nuutinen
- Subjects
Male ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,Epiglottitis ,Tracheotomy ,Bronchoscopy ,Intubation, Intratracheal ,medicine ,Fiber Optic Technology ,Humans ,Intubation ,Seldinger technique ,Infectious Mononucleosis ,Miniaturization ,Laryngoscopy ,medicine.diagnostic_test ,business.industry ,Equipment Design ,General Medicine ,Middle Aged ,respiratory system ,Airway obstruction ,medicine.disease ,Respiration, Artificial ,respiratory tract diseases ,Surgery ,Airway Obstruction ,Anesthesiology and Pain Medicine ,Anesthesia ,Airway management ,business ,Airway - Abstract
Two adult patients with upper airway obstruction due to epiglottitis and infectious mononucleosis requiring urgent airway management are presented. Successful establishment of an open airway was achieved by performing a minitracheotomy using the Seldinger technique followed finally with nasotracheal fibreoptic intubation.
- Published
- 1996
5. Guidelines for anaesthesia care in the Nordic countries
- Author
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Lauri S. Nuutinen, Jørgen Viby-Mogensen, Ola Stenqvist, S. E. Gisvold, Hans Flaatten, B. Tryggvason, and P. H. Rosenberg
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business.industry ,General Medicine ,Scandinavian and Nordic Countries ,medicine.disease ,Medical Records ,Anesthesiology and Pain Medicine ,Anesthesiology ,Environmental protection ,Anesthesia Recovery Period ,Workforce ,Humans ,Medicine ,Anesthesia ,Medical emergency ,business ,Societies, Medical ,Monitoring, Physiologic - Published
- 1992
6. Effect of a non-steroidal anti-inflammatory drug, diclofenac, on haemostasis in patients undergoing total hip replacement
- Author
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P. Ranta, Lauri S. Nuutinen, J. Laitinen, T. Salomäki, and J. Puranen
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Adult ,Male ,Bleeding Time ,Diclofenac ,medicine.medical_treatment ,Placebo ,Arthroscopy ,Bolus (medicine) ,Double-Blind Method ,Bleeding time ,medicine ,Humans ,Thromboplastin ,Knee ,Aged ,Hemostasis ,Pain, Postoperative ,Chemotherapy ,medicine.diagnostic_test ,Platelet Count ,business.industry ,General Medicine ,Middle Aged ,stomatognathic diseases ,Anesthesiology and Pain Medicine ,Anesthesia ,Female ,Partial Thromboplastin Time ,Hip Prosthesis ,business ,Partial thromboplastin time ,medicine.drug - Abstract
Haemostasis was studied in patients receiving diclofenac for postoperative pain relief. Intravenous diclofenac 75 mg over 60 min, followed first by an infusion of 5 mg/h for 15 h and then by 50 mg every 8 h orally was administered to 20 patients undergoing total hip replacement. Eighteen patients receiving a placebo infusion and dextropropoxyfen per os served as controls. The results showed no statistically significant differences between the groups in blood loss, bleeding time (IVY), partial activated thromboplastin time and prothrombin complex assay or in platelet count. The measurements were performed preoperatively, 3 h postoperatively and on the fourth and tenth postoperative days. Plasma concentrations were also determined in ten patients undergoing knee arthroscopy. An i.v. diclofenac infusion of 75 mg over a period of 15 min was administered either once (to half of the patients) or twice. The mean diclofenac concentrations were 28 +/- 5 nmol/ml (+/- s.d.) after 15 min and 36 +/- 12 nmol/ml after the second infusion. The bleeding time in the arthroscopy patients receiving one or two bolus infusions of 75 mg diclofenac remained at the control level. It is concluded that diclofenac given as an intravenous infusion of 75 mg in 60 min, then 5 mg/h for 15 h, followed by 50 mg every 8 h orally, is a safe as dextropropoxyfen for pain relief in patients undergoing major orthopaedic surgery as far as coagulation data are concerned.
- Published
- 1992
7. Susceptibility for homeostatic plasticity is down‐regulated in parallel with maturation of the rat hippocampal synaptic circuitry
- Author
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Huupponen, J., primary, Molchanova, S. M., additional, Taira, T., additional, and Lauri, S. E., additional
- Published
- 2007
- Full Text
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8. Clinical judgement and information seeking by nurses and physicians working with cancer patients
- Author
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Salanterä, S., primary, Eriksson, E., additional, Junnola, T., additional, Salminen, E.K., additional, and Lauri, S., additional
- Published
- 2002
- Full Text
- View/download PDF
9. The β1,6-GlcNAc transferase activity present in hog gastric mucosal microsomes catalyses site-specific branch formation on a long polylactosamine backbone
- Author
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Helin, J, primary, Penttilä, L, additional, Leppänen, A, additional, Maaheimo, H, additional, Lauri, S, additional, Costello, C.E, additional, and Renkonen, O, additional
- Published
- 1997
- Full Text
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10. Catheter-Related Complications of Total Parenteral Nutrition (TPN): A Review
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Jan-Ola Wistbacka and Lauri S. Nuutinen
- Subjects
medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Embolism ,Thrombosis ,Bacterial Infections ,General Medicine ,Thrombophlebitis ,medicine.disease ,Catheterization ,Surgery ,Sepsis ,Catheter ,Anesthesiology and Pain Medicine ,Parenteral nutrition ,Humans ,Medicine ,Parenteral Nutrition, Total ,business ,Intensive care medicine ,Central venous catheter - Published
- 1985
11. Aryl hydrocarbon hydroxylase in lymphocytes and lung tissue from lung cancer patients and controls
- Author
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Olavi Pelkonen, Lauri S. Nuutinen, Risto Pokela, and Niilo T. Kärki
- Subjects
Cancer Research ,medicine.medical_specialty ,Lung Neoplasms ,Lymphocyte ,Biology ,Mixed Function Oxygenases ,Cytochrome P-450 CYP2A6 ,Mice ,Basal (phylogenetics) ,Internal medicine ,medicine ,Animals ,Humans ,Lymphocytes ,Lung cancer ,Benzopyrene Hydroxylase ,Lung ,Cells, Cultured ,chemistry.chemical_classification ,Smoking ,Respiratory disease ,Aryl hydrocarbon hydroxylase ,Middle Aged ,medicine.disease ,Rats ,Enzyme Activation ,medicine.anatomical_structure ,Endocrinology ,Enzyme ,Oncology ,chemistry ,Aryl Hydrocarbon Hydroxylases ,Drug metabolism - Abstract
The inducibility of aryl hydrocarbon hydroxylase (AHH) activity in peripheral mitogen-treated lymphocytes, and of AHH and other monoxygenase activities in lung samples, was studied in 41 patients--34 with pulmonary carcinoma, 4 with a benign lung tumour and 3 with chronic obstructive pulmonary disease. Lymphocyte AHH induction alone was studied in 43 non-smoking and 37 smoking surgical patients. Absolute induced and non-induced AHH activities were at about the same level in the lymphocytes from the lung cancer patients as in those from the non-smoking controls, whereas the activities in smoking controls were about 100% higher. The mean inducibility ratios were very similar in all groups, ranging from 4.4 in the benign tumour patients to 5.4 in both control groups. Thymidine incorporation was on average about 40% lower in the lymphocytes from the lung cancer patients. AHH activity was detectable in all the peripheral lung samples, both normal or tumorous tissue, and its inter-individual variation was more than 67-fold. ECDE activity was also detectable in all the samples studied and its correlation with AHH activity was statistically significant (r = 0.888), suggesting that the same enzyme metabolizes both substrates. ERDE was detectable only in the samples with the highest AHH and ECDE activities. There was no correlation between basal or induced lymphocyte AHH activities and lung tissue AHH activity, but there were statistically significant correlations between lung AHH activity and the inducibility ratio with (r = 0.618) or without correction by thymidine incorporation (r = 0.442). These correlations suggest that there are common regulatory factors for AHH inducibility in different tissues. No significant difference in any drug metabolism parameter measured was observed between the lung cancer patients and the controls.
- Published
- 1987
12. ChemInform Abstract: NICKEL-PROMOTED SYNTHESIS OF CYCLIC BIPHENYLS. TOTAL SYNTHESIS OF ALNUSONE DIMETHYL ETHER
- Author
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M. F. SEMMELHACK and LAURI S. RYONO
- Subjects
General Medicine - Published
- 1975
13. ChemInform Abstract: NICKEL-PROMOTED SYNTHESIS OF CYCLIC BIPHENYLS. TOTAL SYNTHESIS OF ALNUSONE DIMETHYL ETHER
- Author
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SEMMELHACK, M. F., primary and RYONO, LAURI S., additional
- Published
- 1975
- Full Text
- View/download PDF
14. Fluid Therapy Practice in Elective Surgery in Finland
- Author
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NUUTINEN, LAURI S., primary and WISTBACKA, JAN-OLA, additional
- Published
- 1985
- Full Text
- View/download PDF
15. Catheter‐Related Complications of Total Parenteral Nutrition (TPN): A Review.
- Author
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WISTBACKA, JAN‐OLA, primary and NUUTINEN, LAURI S., additional
- Published
- 1985
- Full Text
- View/download PDF
16. Geriatric rehabilitation nursing: developing a model.
- Author
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Routasalo P, Arve S, and Lauri S
- Subjects
- Aged, Attitude of Health Personnel, Family psychology, Health Knowledge, Attitudes, Practice, Health Services Research, Humans, Nurse-Patient Relations, Nursing Evaluation Research, Nursing Process, Nursing Staff organization & administration, Nursing Staff psychology, Organizational Objectives, Patient Care Team organization & administration, Patient Compliance psychology, Philosophy, Nursing, Geriatric Nursing organization & administration, Models, Nursing, Nurse's Role, Rehabilitation Nursing organization & administration
- Abstract
In this paper, we describe a geriatric rehabilitation nursing model developed on the basis of the nursing and rehabilitation literature. That literature comprised some 120 articles addressing the rehabilitation of elderly patients and the work done by nurses in that process, various philosophical questions and the results of geriatric rehabilitation. One-third of these articles has been evaluated on the strength of the articles' evidence, and these are discussed in this paper. The findings show that the main factors in geriatric rehabilitation nursing are the patient with health or functional problems and the nurse with professional values, knowledge and skills. The patient is part of a family and the nurse works as part of a multidisciplinary team. In the geriatric rehabilitation process, the patient and the nurse work in close interaction. The aims of rehabilitation depend upon the patient's commitment to the objective and upon the nurse's commitment to help the patient achieve that objective. A health orientation, goal-oriented work, nursing decision-making and a rehabilitative approach to work are all central to this effort. Work is organized in multidisciplinary teams where nurses have equal responsibilities with other professional staff. Testing and development of the model is ongoing.
- Published
- 2004
- Full Text
- View/download PDF
17. Clinical judgement and information seeking by nurses and physicians working with cancer patients.
- Author
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Salanterä S, Eriksson E, Junnola T, Salminen EK, and Lauri S
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- Finland, Humans, Judgment, Problem Solving, Statistics, Nonparametric, Decision Making, Neoplasms diagnosis, Neoplasms therapy, Nurses, Patient Care Planning, Physicians
- Abstract
This study examined and compared the processes of information collection and clinical judgement by nurses (n=107) and physicians (n=27) working with cancer patients. The data was collected in two university hospitals by means of a computer-simulated case description and the thinking-aloud method. Data interpretation was based on SPSS statistical software and the method of content analysis. Statistical differences between the two groups were tested with non-parametric Kruskal-Wallis Anova or the Mann-Whitney U-test. The Wilcoxon test was applied in pairwise comparisons. Independent questions were analysed by cross-tabulation and Pearson's chi(2). According to the results nurses and physicians apply different approaches to clinical judgement and problem-solving. On the basis of the status statement they received in the program both groups pointed to similar problems and sought a great deal of additional information. However the type of information required was different in the two groups. There were also significant differences in the knowledge base applied for purposes of clinical judgement: nurses tended to rely on personal knowledge, physicians on theory. Physicians were able to identify their patient's major clinical problems, but nurses had more difficulty doing this. On the other hand, nurses took a broader view on the general well-being of patients than physicians did., (Copyright 2002 John Wiley & Sons, Ltd.)
- Published
- 2003
- Full Text
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18. Experiences of security associated with pregnancy and childbirth: a study of pregnant women.
- Author
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Melender HL and Lauri S
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- Adult, Educational Status, Factor Analysis, Statistical, Fear, Female, Finland, Humans, Mothers education, Nurse Midwives psychology, Nurse-Patient Relations, Nursing Methodology Research, Parity, Social Support, Surveys and Questionnaires, Attitude to Health, Mothers psychology, Parturition psychology, Pregnancy psychology, Safety, Trust psychology
- Abstract
The aim of this study was to describe the sense of security associated with pregnancy and childbirth and to identify factors associated with it. Security was conceptualized in accordance with Kaufmann as a human need and as a human value. The instrument used was a questionnaire with a 4-point scale. The sample consisted of 481 pregnant Finnish women. The response rate was 69%. Rotated factor analysis was carried out and sum variables were produced. The effects of various background variables were calculated using the Kruskal-Wallis test and the Mann-Whitney U-test. The elements creating security were social support, knowledge, prenatal health-care experiences, support from the partner, livelihood, positive stories and, in multiparae, positive previous childbearing experiences. The most salient finding concerning factors related to security was that women who had no pregnancy-related problems in the current pregnancy reported social support, prenatal health-care experiences and support from the partner as security-creating elements more often than women with such problems. This was the only factor related to manifestation of security. The findings suggest that all pregnant women should be assisted by professionals to find security-creating elements in their particular situation to promote and strengthen the sense of security, paying special attention to women with pregnancy-related problems.
- Published
- 2002
- Full Text
- View/download PDF
19. An exploratory study of clinical decision-making in five countries.
- Author
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Lauri S, Salanterä S, Chalmers K, Ekman SL, Kim HS, Käppeli S, and MacLeod M
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- Canada, Cognitive Science, Europe, Factor Analysis, Statistical, Humans, Intuition, Logic, United States, Decision Making, Models, Psychological, Nursing Assessment
- Abstract
Purpose: To identify the cognitive processes nurses use in their decision-making in long- and short-term care settings in five countries, and the demographic variables associated with their decision-making. METHOD AND SAMPLES: The instrument used was a 56-item questionnaire that has been shown to be reliable in earlier studies. The sample consisted of five convenience samples of registered nurses working in either geriatric wards (n = 236) or acute medical-surgical wards (n = 223) in hospitals or nursing homes in Canada, Finland, Sweden, Switzerland, and the United States., Findings: Five models of decision-making were identified on the basis of factor analysis. They represent both analytical and intuitive cognitive processes. Analytical cognitive processes were emphasized in information collection, problem definition, and planning of care, and intuitive cognitive processes were emphasized in planning, implementing, and evaluating care. Professional education, practical experience, field of practice, and type of knowledge were significantly associated with decision-making models as well as with country of residence of the participants. The highest proportion of analytically oriented decision-makers was found among nurses in long-term care, the decision-making of nurses in short-term care was more intuitively oriented., Conclusions: The results indicate that decision-making of participants varied from country to country and in different nursing situations. Future research should be focused on reasons for these differences, the relationship between the task and the nurses' type of knowledge, and how nurses use their knowledge to make decisions in different nursing situations.
- Published
- 2001
- Full Text
- View/download PDF
20. Informational and emotional support for cancer patients' relatives.
- Author
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Eriksson E and Lauri S
- Subjects
- Adult, Emotions, Female, Finland, Humans, Male, Middle Aged, Needs Assessment, Neoplasms nursing, Nursing Evaluation Research, Quality of Health Care, Surveys and Questionnaires, Attitude to Health, Family psychology, Neoplasms psychology, Patient Education as Topic organization & administration, Social Support
- Abstract
The purpose of this study was to find out what cancer patients' relatives think about the actions of health care professionals in terms of providing informational and emotional support. The sample consisted of 168 relatives of patients from oncological wards all over Finland. The data were collected with a questionnaire specifically developed for this study. Non-parametric tests were used for statistical analysis. The results clearly highlighted the importance of informing relatives about the patient's illness. However, less than one-third of the relatives said they received much information. Relatives' need for emotional support was clearly at a lower level than their need for information. Even so, only very little support was provided in relation to relatives' needs.
- Published
- 2000
- Full Text
- View/download PDF
21. Patients' and nurses' assessment of cancer pain.
- Author
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Hovi SL and Lauri S
- Subjects
- Adult, Aged, Aged, 80 and over, Female, Finland, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Nursing Staff, Hospital education, Oncology Nursing, Reproducibility of Results, Surveys and Questionnaires, Attitude of Health Personnel, Attitude to Health, Neoplasms complications, Nursing Assessment methods, Nursing Staff, Hospital psychology, Pain diagnosis, Pain psychology, Pain Measurement nursing, Pain Measurement psychology
- Abstract
The purpose of this study was to examine hospitalised cancer patients' and nurses' assessment of patients' cancer pain and to compare them. The data were collected from 51 patient-nurse pairs in two hospitals from oncological and medical clinics. Each nurse and patient took part in the study no more than once. The data were collected with a structured interview and the questionnaire. The intensity of pain was measured with a visual analogue scale (VAS) and the Finnish version of the McGill Pain Questionnaire (FPQ). The results showed that the differences between patients' and nurses' assessments were statistically significant for most intensive pain and for acceptable pain. In both cases nurses' assessments of the intensity of pain were lower than patients' assessments. The nurses identified 40 words in the verbal FPQ that the patients used in describing their experiences of pain. The words used most often by patients were agonizing, tender, wave-like and radiant. The word that the nurses used most often was that of intense. Nurses' knowledge about pain medication in general and morphine in particular was clearly associated with the differences observed in estimates of the intensity of pain. Nurses with poor knowledge underestimated the patients' most intensive experiences of pain. The difference was statistically significant.
- Published
- 1999
- Full Text
- View/download PDF
22. Oncology nurses' attitudes towards alternative medicine.
- Author
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Salmenperä L, Suominen T, and Lauri S
- Subjects
- Adult, Communication, Health Knowledge, Attitudes, Practice, Humans, Middle Aged, Nurse-Patient Relations, Patient Education as Topic, Quackery, Surveys and Questionnaires, Attitude of Health Personnel, Complementary Therapies, Neoplasms therapy, Nursing Staff, Hospital psychology, Oncology Nursing
- Abstract
Little is known about nurses' attitudes towards alternative medicine. The purpose of this study was to describe attitudes towards alternative medicine among nurses working on oncology wards in three university and one central hospital in Finland. The data were collected with a questionnaire specifically developed for this project. The response rate was 68.1% (n = 92). The nurses did not regard alternative medicine as a safe and natural method in the treatment of cancer. On the contrary, many nurses believed that alternative therapies are offered by quack doctors for financial gain. However, the nurses considered it important that cancer patients have the opportunity to talk about their use of alternative medicine both with nurses and physicians. Overall the results indicated that nurses' attitudes are for the most part negative. An interesting question that deserves further attention is whether this attitude is reflected in nursing practice.
- Published
- 1998
- Full Text
- View/download PDF
23. Decision-making models in different fields of nursing.
- Author
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Lauri S and Salanterä S
- Subjects
- Critical Care, Factor Analysis, Statistical, Finland, Humans, Long-Term Care, Nursing Evaluation Research, Perioperative Nursing, Psychiatric Nursing, Public Health Nursing, Surveys and Questionnaires, Decision Making, Decision Support Techniques, Models, Nursing, Nursing Process, Nursing Staff psychology, Specialties, Nursing
- Abstract
The purpose of this study was to identify the decision-making models used by nurses in different fields of nursing and to find out which variables explain the use of those models. The instrument for the project was developed on the basis of existing decision-making theories and earlier studies on nurses' decision making. The sample consisted of 483 Finnish nurses from five fields of nursing: long-term care, short-term medical-surgical care, critical care, health care, and psychiatric care. The statistical analyses consisted of factor analysis, factor scores, and correspondence analysis. Five different models of nursing decision making were identified. The nature of the nursing task and the nursing context showed associations with decision making on all models. The structure of knowledge and nurses' practical experience did not provide an explanation for nurses' decision making on any model.
- Published
- 1998
- Full Text
- View/download PDF
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