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35 results on '"Lau, Wai"'

4. Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)

Author

Zhang, Shiqing, primary, Sun, Peng, additional, Lin, Kaili, additional, Chan, Florence Hiu Ling, additional, Gao, Qi, additional, Lau, Wai Fung, additional, Roy, Vellaisamy A. L., additional, Zhang, Hongqi, additional, Lai, King Wai Chiu, additional, Huang, Zhifeng, additional, and Yung, Ken Kin Lam, additional

Published
2019
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5. Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats

Author

Zhang, Shiqing, primary, Sun, Peng, additional, Lin, Kaili, additional, Chan, Florence Hiu Ling, additional, Gao, Qi, additional, Lau, Wai Fung, additional, Roy, Vellaisamy A. L., additional, Zhang, Hongqi, additional, Lai, King Wai Chiu, additional, Huang, Zhifeng, additional, and Yung, Ken Kin Lam, additional

Published
2019
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25. Follicular thyroid carcinoma

Author

Chow, Sin-Ming, primary, Law, Stephen C. K., additional, Mendenhall, William M., additional, Au, Siu-Kie, additional, Yau, Stephen, additional, Yuen, Kam-Tong, additional, Law, Chi-Ching, additional, and Lau, Wai-Hon, additional

Published
2002
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34. Measuring angle of progression by transperineal ultrasonography to predict successful instrumental and cesarean deliveries during prolonged second stage of labor.

Author

Chan VYT, Lau WL, So MKP, and Leung WC

Subjects
Adult, Female, Hong Kong, Humans, Predictive Value of Tests, Pregnancy, Prospective Studies, Uterine Contraction, Cesarean Section statistics & numerical data, Labor Presentation, Labor Stage, Second, Ultrasonography, Prenatal methods, Vacuum Extraction, Obstetrical statistics & numerical data
Abstract

Objective: To compare the angle of progression (AoP) measured by transperineal ultrasonography before indicating an instrumental delivery or cesarean delivery., Methods: A prospective observational study was conducted among women with singleton term pregnancies with prolonged second stage of labor at Kwong Wah Hospital, Hong Kong, China, between May 16, 2011, and May 25, 2016. Transabdominal and transperineal ultrasonography were performed to determine fetal head position and AoP, respectively, both at rest and during uterine contraction with pushing. Mode of delivery was decided after vaginal examination without relying on ultrasonography., Results: Of 143 women, 116 underwent successful instrumental delivery and 27 underwent cesarean delivery. Median AoP was 153.0° in the instrumental group versus 139.0° in the cesarean group at rest (P<0.001), and 182.5° in the instrumental group versus 156.5° in the cesarean group during contraction (P<0.001). The best predictive cutoff AoP for successful instrumental delivery was 138.7° at rest (sensitivity 86.2%, specificity 51.9%) and 160.9° during contraction (sensitivity 87.1%, specificity 74.1%). No between-group differences in AoP were found for ease of vacuum extraction at rest (P=0.457) or during contraction with pushing (P=0.095)., Conclusion: The AoP predicted approximately 80% of successful instrumental deliveries performed for prolonged second stage of labor., (© 2018 International Federation of Gynecology and Obstetrics.)

Published
2019
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35. Follicular thyroid carcinoma: prognostic factors and the role of radioiodine.

Author

Chow SM, Law SC, Mendenhall WM, Au SK, Yau S, Yuen KT, Law CC, and Lau WH

Subjects
Adenocarcinoma, Follicular radiotherapy, Adenocarcinoma, Follicular surgery, Adolescent, Adult, Aged, Aged, 80 and over, Child, Combined Modality Therapy, Female, Humans, Iodine Radioisotopes therapeutic use, Male, Middle Aged, Prognosis, Survival Analysis, Thyroid Neoplasms radiotherapy, Thyroid Neoplasms surgery, Thyroidectomy, Treatment Outcome, Adenocarcinoma, Follicular pathology, Thyroid Neoplasms pathology
Abstract

Background: The objective of this study was to investigate the patterns of recurrence, various prognostic factors, and the role of radioiodine in the treatment of patients with follicular thyroid carcinoma (FTC)., Methods: The clinical outcomes of 215 patients with FTC who were treated at a single institution were analyzed retrospectively. The mean follow-up was 10.8 years., Results: The actuarial rates of cause specific survival (CSS), locoregional (LR) control, and freedom from distant metastasis (DM) at 10 years were 81%, 83%, and 72.3%, respectively. The independent prognostic factors for survival were metastasis at presentation (relative risk [RR], 47.7), radioiodine (RAI) treatment (RR, 0.25), extrathyroidal extension (RR, 3.8), and the postoperative absence of macroscopic disease in the neck region (RR, 0.06). In patients who were treated with RAI, both the LR failure rate (RR, 0.24) and the mortality rate (RR, 0.25) were reduced to about 25%. Subgroup analysis revealed that RAI improved the survival of patients with DM at presentation (RR, 0.17) and improved the LR control rate in patients who had no DM at presentation (RR, 0.13). For patients who underwent total thyroidectomy with negative resection margins, RAI significantly reduced the rate of LR recurrence (RR, 0.05). Patients with the minimally invasive type of FTC had a good prognosis. The 10-year rates for CSS, LR control, and freedom from DM were 97.6%, 100%, and 90.6%, respectively. The prognosis of patients with frankly invasive FTC was much poorer. The 10-year rates for CSS, LR control, and freedom from DM were 66.7%, 100%, and 45%, respectively., Conclusions: RAI is an effective treatment for patients with FTC. It was associated with improved survival rates and fewer recurrences., (Copyright 2002 American Cancer Society.)

Published
2002
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