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Abstract Aim Our study aimed at investigating the risk perception of nurses and related factors in the era of COVID‐19 period. Design Cross‐sectional study. Methods Four hundred and forty‐two participants completed an online questionnaire relating to their risk perception on public health emergencies. Data were collected between 25 November 2020 and 1 December 2020. Kruskal–Wallis test, Mann–Whitney U test and Ordinal logistic regression analysis were used to examine factors impacting on risk perception. Results 65.2% of nurses' risk perception of COVID‐19 was the moderate level even below the moderate level in the postperiod of COVID‐19. Kruskal–Wallis test results indicated significant differences in gender, age, education status, working years, professional title, postlevel, COVID‐19 contact experience, marital status and health status (p