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27 results on '"LEE, YOON JUNG"'

4. Resistive Switching Memory: Lead‐Free Dual‐Phase Halide Perovskites for Preconditioned Conducting‐Bridge Memory (Small 41/2020)

Author

Han, Ji Su, primary, Le, Quyet Van, additional, Kim, Hyojung, additional, Lee, Yoon Jung, additional, Lee, Da Eun, additional, Im, In Hyuk, additional, Lee, Min Kyung, additional, Kim, Seung Ju, additional, Kim, Jaehyun, additional, Kwak, Kyung Ju, additional, Choi, Min‐Ju, additional, Lee, Sol A, additional, Hong, Kootak, additional, Kim, Soo Young, additional, and Jang, Ho Won, additional

Published
2020
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5. Lead‐Free Dual‐Phase Halide Perovskites for Preconditioned Conducting‐Bridge Memory

Author

Han, Ji Su, primary, Le, Quyet Van, additional, Kim, Hyojung, additional, Lee, Yoon Jung, additional, Lee, Da Eun, additional, Im, In Hyuk, additional, Lee, Min Kyung, additional, Kim, Seung Ju, additional, Kim, Jaehyun, additional, Kwak, Kyung Ju, additional, Choi, Min‐Ju, additional, Lee, Sol A, additional, Hong, Kootak, additional, Kim, Soo Young, additional, and Jang, Ho Won, additional

Published
2020
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6. High Hole Mobility Inorganic Halide Perovskite Field‐Effect Transistors with Enhanced Phase Stability and Interfacial Defect Tolerance

Author

Jae Young Kim, In Hyuk Im, Ho Won Jang, Kyung Ju Kwak, Jung Hun Lee, Ji Su Han, Tae Hyung Lee, Seung Ju Kim, Lee Yoon-Jung, Da Eun Lee, and Jun Min Suh

Subjects
Electron mobility, Materials science, Passivation, Phase stability, business.industry, Optoelectronics, Halide, Field-effect transistor, business, Electronic, Optical and Magnetic Materials, Perovskite (structure)
Published
2021
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7. Resistive Switching Memory: Lead‐Free Dual‐Phase Halide Perovskites for Preconditioned Conducting‐Bridge Memory (Small 41/2020)

Author

Ho Won Jang, Kyung Ju Kwak, Hyo Jung Kim, Soo Young Kim, Ji Su Han, In Hyuk Im, Jae-Hyun Kim, Min Kyung Lee, Kootak Hong, Da Eun Lee, Sol A Lee, Seung Ju Kim, Lee Yoon-Jung, Quyet Van Le, and Min-Ju Choi

Subjects
Materials science, business.industry, Phase (waves), Halide, General Chemistry, Bridge (interpersonal), Dual (category theory), Biomaterials, Optoelectronics, General Materials Science, Resistive switching memory, business, Lead (electronics), Biotechnology
Published
2020
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10. Assessment of mitophagy in mt‐Keima Drosophila revealed an essential role of the PINK1‐Parkin pathway in mitophagy induction in vivo

Author

Kim, Young Yeon, primary, Um, Jee‐Hyun, additional, Yoon, Jeong‐Hyun, additional, Kim, Hyunjin, additional, Lee, Da‐Ye, additional, Lee, Yoon Jung, additional, Jee, Hye Jin, additional, Kim, Young Mi, additional, Jang, Jae Sung, additional, Jang, Yoon‐Gu, additional, Chung, Jongkyeong, additional, Park, Hwan Tae, additional, Finkel, Toren, additional, Koh, Hyongjong, additional, and Yun, Jeanho, additional

Published
2019
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11. Osteoclastogenesis is enhanced by activated B cells but suppressed by activated CD8+ T cells

Author

Lee Yoon-Jung, Kyung Mi Woo, Hyun-Man Kim, Byoung S. Kwon, Seong-Hee Ko, Su-Jin Park, and Youngnim Choi

Subjects
musculoskeletal diseases, medicine.medical_specialty, ZAP70, Immunology, Biology, Molecular biology, Interleukin 21, medicine.anatomical_structure, Endocrinology, Osteoclast, RANKL, Internal medicine, medicine, biology.protein, Immunology and Allergy, Cytotoxic T cell, IL-2 receptor, Activated Lymphocyte, B cell
Abstract

Host immune response is known to contribute to the progression of periodontitis, and alveolar bone destruction in periodontitis is associated with enhanced osteoclast activity. Therefore, we evaluated the roles of activated lymphocyte subsets in osteoclastogenesis. Osteoclast precursors were co-cultured with activated lymphocytes (B, CD4(+) T, CD8(+) T) in the presence of either macrophage colony-stimulating factor (M-CSF) alone or M-CSF plus soluble receptor activator of NF-kappaB ligand (sRANKL), and subsequent differentiation into active osteoclasts was evaluated by a resorption assay. The activated B and CD4(+) cells, but not CD8(+) T cells, induced osteoclast differentiation in the presence of M-CSF alone. In the presence of M-CSF and sRANKL, B cells induced the formation of small but highly active osteoclasts and increased resorption, while CD8(+) T cells profoundly suppressed osteoclastogenesis. Co-culture using an insert well or supernatant suggested that both B and CD8(+) T cells acted on osteoclasts mostly via soluble proteins. Activated B cells expressed many osteoclastogenic factors including RANKL, TNF-alpha, IL-6, MIP-1alpha, and MCP-3. CD8(+) T cells expressed a substantial amount of osteoprotegerin (OPG) along with RANKL. However, blocking antibody to OPG did not reverse the suppression by CD8(+) T cells, suggesting that other factor(s) are involved. Taken together, activated B cells promoted osteoclastogenesis, while CD8(+) T cells inhibited the osteoclast formation via direct interaction. The results imply the importance of lymphocyte subpopulations in the development of periodontitis.

Published
2001
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27. Effect of HMGCR variant alleles on low-density lipoprotein cholesterol-lowering response to atorvastatin in healthy Korean subjects.

Author

Chung JY, Cho SK, Oh ES, Lee DH, Lim LA, Jang SB, Lee YJ, Park K, and Park MS

Subjects
Adult, Atorvastatin, Female, Genotype, Humans, Hydroxymethylglutaryl CoA Reductases genetics, Male, Young Adult, Asian People genetics, Cholesterol, LDL blood, Heptanoic Acids pharmacology, Hydroxymethylglutaryl CoA Reductases metabolism, Hypolipidemic Agents pharmacology, Polymorphism, Genetic, Pyrroles pharmacology
Abstract

The investigators quantified the relationship between the genetic polymorphism of HMGCR (3-hydroxy-3-methylglutaryl coenzyme A reductase) and the low-density lipoprotein cholesterol (LDL-C)-lowering effects of atorvastatin in a prospective clinical study. Twenty-four healthy participants were grouped into HMGCR rs3846662 GG (n = 13) and AA (n = 11) genotypes and given atorvastatin (20 mg/d) for 14 days. Serum levels of LDL-C, high-density lipoprotein cholesterol, total cholesterol, triglycerides, and creatinine kinase (CK) were measured before (day 1) and 7, 13, 14, 15, 16, 21, and 28 days after dosing initiation. Blood samples for pharmacokinetics were taken on days 14 through 16. The levels of LDL-C in the GG group were significantly higher than in the AA group at all observation times, with mean differences of 18% to 33% (P < .05). The area under the LDL-C-time curve and the minimum value of LDL-C in the GG group were 24% and 23% higher than in the AA group, respectively (P < .01). There was no significant difference in other lipids, CK, and pharmacokinetic parameters. The HMGCR rs3846662 GG genotype was quantitatively documented to be a significant determinant for higher LDL-C level in basal state and possibly in response to atorvastatin.

Published
2012
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