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Your search keyword '"Komura T."' showing total 12 results
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12 results on '"Komura T."'

1. Anti‐BP180 , pruritus, and thymus and activation‐regulated chemokines as surrogate markers for disease activity in bullous pemphigoid

Author

Wada, S., primary, Komori, T., additional, de Jesus, C.S., additional, Nomura, T., additional, Komura, T., additional, Yonekura, S., additional, Shibuya, R., additional, Adachi, E., additional, Sakurai, Y., additional, Ishikawa, M., additional, Usui, S., additional, Kambe, N., additional, and Kabashima, K., additional

Published
2022
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2. Data Driven Crowd Motion Control with Multi-touch Gestures

Author

Shen, Y, Henry, J, Wang, H, Ho, ESL, Komura, T, and Shum, HPH

Abstract

Controlling a crowd using multi‐touch devices appeals to the computer games and animation industries, as such devices provide a high‐dimensional control signal that can effectively define the crowd formation and movement. However, existing works relying on pre‐defined control schemes require the users to learn a scheme that may not be intuitive. We propose a data‐driven gesture‐based crowd control system, in which the control scheme is learned from example gestures provided by different users. In particular, we build a database with pairwise samples of gestures and crowd motions. To effectively generalize the gesture style of different users, such as the use of different numbers of fingers, we propose a set of gesture features for representing a set of hand gesture trajectories. Similarly, to represent crowd motion trajectories of different numbers of characters over time, we propose a set of crowd motion features that are extracted from a Gaussian mixture model. Given a run‐time gesture, our system extracts the K nearest gestures from the database and interpolates the corresponding crowd motions in order to generate the run‐time control. Our system is accurate and efficient, making it suitable for real‐time applications such as real‐time strategy games and interactive animation controls.

Published
2018

12. Optimization of surface-immobilized extracellular matrices for the proliferation of neural progenitor cells derived from induced pluripotent stem cells.

Author

Komura T, Kato K, Konagaya S, Nakaji-Hirabayashi T, and Iwata H

Subjects
Animals, Cell Differentiation, Mice, Cell Culture Techniques methods, Cell Proliferation, Extracellular Matrix metabolism, Immobilized Proteins metabolism, Induced Pluripotent Stem Cells physiology, Neural Stem Cells physiology, Tissue Expansion methods
Abstract

Neural progenitor cells derived from induced pluripotent stem cells have been considered as a potential source for cell-transplantation therapy of central nervous disorders. However, efficient methods to expand neural progenitor cells are further required for their clinical applications. In this study, a protein array was fabricated with nine extracellular matrices and used to screen substrates suitable for the expansion of neural progenitor cells derived from mouse induced pluripotent stem cells. The results showed that neural progenitor cells efficiently proliferated on substrates with immobilized laminin-1, laminin-5, or Matrigel. Based on this result, further attempts were made to develop clinically compliant substrates with immobilized polypeptides that mimic laminin-1, one of the most effective extracellular matrices as identified in the array-based screening. We used here recombinant DNA technology to prepare polypeptide containing the globular domain 3 of laminin-1 and immobilized it onto glass-based substrates. Our results showed that neural progenitor cells selectively proliferated on substrate with the immobilized polypeptide while maintaining their differentiated state., (© 2015 Wiley Periodicals, Inc.)

Published
2015
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