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Your search keyword '"Kench, James G"' showing total 26 results
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26 results on '"Kench, James G"'

1. Comprehensive methylome sequencing reveals prognostic epigenetic biomarkers for prostate cancer mortality

Author

Pidsley, Ruth, primary, Lam, Dilys, additional, Qu, Wenjia, additional, Peters, Timothy J., additional, Luu, Phuc‐Loi, additional, Korbie, Darren, additional, Stirzaker, Clare, additional, Daly, Roger J., additional, Stricker, Phillip, additional, Kench, James G., additional, Horvath, Lisa G., additional, and Clark, Susan J., additional

Published
2022
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2. WHO Classification of Tumours fifth edition: evolving issues in the classification, diagnosis, and prognostication of prostate cancer

Author

Kench, James G, primary, Amin, Mahul B, additional, Berney, Daniel M, additional, Compérat, Eva M, additional, Cree, Ian A, additional, Gill, Anthony J, additional, Hartmann, Arndt, additional, Menon, Santosh, additional, Moch, Holger, additional, Netto, George J, additional, Raspollini, Maria R, additional, Rubin, Mark A, additional, Tan, Puay Hoon, additional, Tsuzuki, Toyonori, additional, Turjalic, Samra, additional, van der Kwast, Theo H, additional, Zhou, Ming, additional, and Srigley, John R, additional

Published
2022
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3. Dataset for the reporting of carcinoma of the exocrine pancreas: recommendations from the International Collaboration on Cancer Reporting (ICCR)

Author

Verbeke, Caroline, primary, Webster, Fleur, additional, Brosens, Lodewijk, additional, Campbell, Fiona, additional, Del Chiaro, Marco, additional, Esposito, Irene, additional, Feakins, Roger M, additional, Fukushima, Noriyoshi, additional, Gill, Anthony J, additional, Kakar, Sanjay, additional, Kench, James G, additional, Krasinskas, Alyssa M, additional, Laethem, Jean‐Luc, additional, Schaeffer, David F, additional, and Washington, Kay, additional

Published
2021
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4. Prostate cancer grading, time to go back to the future

Author

Egevad, Lars, primary, Delahunt, Brett, additional, Bostwick, David G., additional, Cheng, Liang, additional, Evans, Andrew J., additional, Gianduzzo, Troy, additional, Graefen, Markus, additional, Hugosson, Jonas, additional, Kench, James G., additional, Leite, Katia R.M., additional, Oxley, Jon, additional, Sauter, Guido, additional, Srigley, John R., additional, Stattin, Pär, additional, Tsuzuki, Toyonori, additional, Yaxley, John, additional, and Samaratunga, Hemamali, additional

Published
2020
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5. An analysis of a multiple biomarker panel to better predict prostate cancer metastasis after radical prostatectomy

Author

Zhang, Alison Y., primary, Chiam, Karen, additional, Haupt, Ygal, additional, Fox, Stephen, additional, Birch, Simone, additional, Tilley, Wayne, additional, Butler, Lisa M., additional, Knudsen, Karen, additional, Comstock, Clay, additional, Rasiah, Krishan, additional, Grogan, Judith, additional, Mahon, Kate L., additional, Bianco-Miotto, Tina, additional, Ricciardelli, Carmela, additional, Böhm, Maret, additional, Henshall, Susan, additional, Delprado, Warick, additional, Stricker, Phillip, additional, Horvath, Lisa G., additional, and Kench, James G., additional

Published
2018
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6. Utility of Pathology Imagebase for standardisation of prostate cancer grading

Author

Egevad, Lars, primary, Delahunt, Brett, additional, Berney, Daniel M, additional, Bostwick, David G, additional, Cheville, John, additional, Comperat, Eva, additional, Evans, Andrew J, additional, Fine, Samson W, additional, Grignon, David J, additional, Humphrey, Peter A, additional, Hörnblad, Jonas, additional, Iczkowski, Kenneth A, additional, Kench, James G, additional, Kristiansen, Glen, additional, Leite, Katia R M, additional, Magi‐Galluzzi, Cristina, additional, McKenney, Jesse K, additional, Oxley, Jon, additional, Pan, Chin‐Chen, additional, Samaratunga, Hemamali, additional, Srigley, John R, additional, Takahashi, Hiroyuki, additional, True, Lawrence D, additional, Tsuzuki, Toyonori, additional, van der Kwast, Theo, additional, Varma, Murali, additional, Zhou, Ming, additional, and Clements, Mark, additional

Published
2018
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7. Effect of FAK inhibitor VS‐6063 (defactinib) on docetaxel efficacy in prostate cancer

Author

Lin, Hui‐Ming, primary, Lee, Brian Y., additional, Castillo, Lesley, additional, Spielman, Calan, additional, Grogan, Judith, additional, Yeung, Nicole K., additional, Kench, James G., additional, Stricker, Phillip D., additional, Haynes, Anne‐Maree, additional, Centenera, Margaret M., additional, Butler, Lisa M., additional, Shreeve, S. Martin, additional, Horvath, Lisa G., additional, and Daly, Roger J., additional

Published
2018
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8. Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer

Author

Kalsbeek, Anton M. F., primary, Chan, Eva K. F., additional, Grogan, Judith, additional, Petersen, Desiree C., additional, Jaratlerdsiri, Weerachai, additional, Gupta, Ruta, additional, Lyons, Ruth J., additional, Haynes, Anne-Maree, additional, Horvath, Lisa G., additional, Kench, James G., additional, Stricker, Phillip D., additional, and Hayes, Vanessa M., additional

Published
2017
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13. INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival

Author

Rynkiewicz, Natalie K., primary, Fedele, Clare G., additional, Chiam, Karen, additional, Gupta, Ruta, additional, Kench, James G., additional, Ooms, Lisa M., additional, McLean, Catriona A., additional, Giles, Graham G., additional, Horvath, Lisa G., additional, and Mitchell, Christina A., additional

Published
2014
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16. High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy

Author

Savdie, Richard, primary, Horvath, Lisa G., additional, Benito, Ruth Pe, additional, Rasiah, Krishan K., additional, Haynes, Anne-Maree, additional, Chatfield, Mark, additional, Stricker, Phillip D., additional, Turner, Jennifer J., additional, Delprado, Warwick, additional, Henshall, Susan M., additional, Sutherland, Robert L., additional, and Kench, James G., additional

Published
2011
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18. LMO4 expression in squamous cell carcinoma of the anterior tongue

Author

Kwong, Rhonda A, primary, Scarlett, Christopher J, additional, Kalish, Larry H, additional, Cole, Ian E, additional, Kench, James G, additional, Sum, Eleanor YM, additional, Musgrove, Elizabeth A, additional, Henshall, Susan M, additional, Lindeman, Geoffrey J, additional, Biankin, Andrew V, additional, Visvader, Jane E, additional, and Sutherland, Robert L, additional

Published
2011
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23. Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression

Author

Horvath, Lisa G., primary, Henshall, Susan M., additional, Kench, James G., additional, Turner, Jennifer J., additional, Golovsky, David, additional, Brenner, Phillip C., additional, O'Neill, Gordon F., additional, Kooner, Raji, additional, Stricker, Phillip D., additional, Grygiel, John J., additional, and Sutherland, Robert L., additional

Published
2004
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26. Clinical and pathologic features of familial pancreatic cancer.

Author

Humphris JL, Johns AL, Simpson SH, Cowley MJ, Pajic M, Chang DK, Nagrial AM, Chin VT, Chantrill LA, Pinese M, Mead RS, Gill AJ, Samra JS, Kench JG, Musgrove EA, Tucker KM, Spigelman AD, Waddell N, Grimmond SM, and Biankin AV

Subjects
Aged, Alcohol Drinking epidemiology, Carcinoma epidemiology, Carcinoma pathology, Carcinoma, Pancreatic Ductal epidemiology, Carcinoma, Pancreatic Ductal pathology, Case-Control Studies, Cohort Studies, Diabetes Mellitus epidemiology, Endometrial Neoplasms genetics, Female, Humans, Male, Melanoma genetics, Middle Aged, Neoplasms, Multiple Primary epidemiology, Neoplasms, Multiple Primary pathology, Pancreatic Neoplasms epidemiology, Pancreatic Neoplasms pathology, Risk Factors, Smoking epidemiology, Carcinoma genetics, Carcinoma, Pancreatic Ductal genetics, Neoplasms, Multiple Primary genetics, Pancreatic Neoplasms genetics
Abstract

Background: Inherited predisposition to pancreatic cancer contributes significantly to its incidence and presents an opportunity for the development of early detection strategies. The genetic basis of predisposition remains unexplained in a high proportion of patients with familial PC (FPC)., Methods: Clinicopathologic features were assessed in a cohort of 766 patients who had been diagnosed with pancreatic ductal adenocarcinoma (PC). Patients were classified with FPC if they had ≥1 affected first-degree relatives; otherwise, they were classified with sporadic PC (SPC)., Results: The prevalence of FPC in this cohort was 8.9%. In FPC families with an affected parent-child pair, 71% in the subsequent generation were 12.3 years younger at diagnosis. Patients with FPC had more first-degree relatives who had an extrapancreatic malignancy (EPM) (42.6% vs 21.2; P<.0001), particularly melanoma and endometrial cancer, but not a personal history of EPM. Patients with SPC were more likely to be active smokers, have higher cumulative tobacco exposure, and have fewer multifocal precursor lesions, but these were not associated with differences in survival. Long-standing diabetes mellitus (>2 years) was associated with poor survival in both groups., Conclusions: FPC represents 9% of PC, and the risk of malignancy in kindred does not appear to be confined to the pancreas. Patients with FPC have more precursor lesions and include fewer active smokers, but other clinicopathologic factors and outcome are similar to those in patients with SPC. Furthermore, some FPC kindreds may exhibit anticipation. A better understanding of the clinical features of PC will facilitate efforts to uncover novel susceptibility genes and the development of early detection strategies., (© 2014 American Cancer Society.)

Published
2014
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