1. Pathological ankle-brachial index is equivalent of advanced age in acute coronary syndromes
- Author
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Josep Guindo, Vicente Bertomeu-Martínez, Manuel Anguita, Luis Rodríguez-Padial, Pilar Mazón, en nombre de los investigadores del estudio Pamisca, Federico Soria, Pedro Morillas, José Ramón González-Juanatey, Juan Quiles, Vicente Bertomeu-González, and Alberto Cordero
- Subjects
medicine.medical_specialty ,Acute coronary syndrome ,business.industry ,Proportional hazards model ,medicine.medical_treatment ,Clinical Biochemistry ,Three Vessel Coronary Disease ,General Medicine ,Revascularization ,medicine.disease ,Biochemistry ,Surgery ,Blood pressure ,Internal medicine ,Predictive value of tests ,Severity of illness ,medicine ,Prospective cohort study ,business - Abstract
Eur J Clin Invest 2011; 41 (12): 1268–1274 Abstract Background Age is one the factors associated with poor prognosis in acute coronary syndromes (ACS) and elderly patients are a high-risk collective with few parameters for mid-term cardiovascular stratification. We aimed to assess the predictive value of ankle–brachial index (ABI) in patients (> 75 years) for 1-year mortality after an ACS. Materials and methods Prospective, observational and multicentre study of ACS patients in whom ABI was assessed during hospitalization. Results A total of 1·054 patients were included, mean age 66·6 (11·7) years from whom 26·6% were > 75 years. Elderly patients showed more history of cardiovascular disease and higher prevalence of all risk factors, except current smoking. Angiography and revascularization were performed less frequently in the elderly. Patients > 75 years showed higher presence of three vessel coronary disease and received fewer guideline-recommended treatments. Patients who died through the follow-up, mean time 387·9 ± 7·2 days, had lower ABI (0·73 ± 0·24 vs. 0·92 ± 0·22; P 75 years (HR: 2·30; IC 95% 1·26–4·18; P 0·90 and young patients with ABI
- Published
- 2011