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12 results on '"Johnson, Jennifer M."'

1. Predictive capacity of immune‐related adverse events and cytokine profiling in neoadjuvant immune checkpoint inhibitor trials for head and neck squamous cell carcinoma

Author

Alnemri, Angela E., primary, Tekumalla, Sruti, additional, Moroco, Annie E., additional, Vathiotis, Ioannis, additional, Tuluc, Madalina, additional, Gargano, Stacey, additional, Zhan, Tingting, additional, Cognetti, David M., additional, Curry, Joseph M., additional, Argiris, Athanassios, additional, Linnenbach, Alban, additional, South, Andrew P., additional, Harshyne, Larry A., additional, Johnson, Jennifer M., additional, and Luginbuhl, Adam J., additional

Published
2024
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2. Effect of preoperative programmed death‐1 or programmed death ligand‐1 immune check point inhibition on complications after surgery for primary head and neck cancer

Author

Philips, Ramez, primary, Alnemri, Angela, additional, Amin, Dev, additional, Patel, Jena, additional, Topf, Michael C., additional, Johnson, Jennifer M., additional, BarAd, Voichita, additional, Axelrod, Rita, additional, Argiris, Athanassios, additional, Fundakowski, Christopher, additional, Luginbuhl, Adam J., additional, Cognetti, David M., additional, and Curry, Joseph M., additional

Published
2023
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3. Phase 1/2a, open‐label, multicenter study ofRM‐1929 photoimmunotherapy in patients with locoregional, recurrent head and neck squamous cell carcinoma

Author

Cognetti, David M., primary, Johnson, Jennifer M., additional, Curry, Joseph M., additional, Kochuparambil, Samith T., additional, McDonald, Darren, additional, Mott, Frank, additional, Fidler, Mary J., additional, Stenson, Kerstin, additional, Vasan, Nilesh R., additional, Razaq, Mohammad A., additional, Campana, John, additional, Ha, Patrick, additional, Mann, Grace, additional, Ishida, Kosuke, additional, Garcia‐Guzman, Miguel, additional, Biel, Merrill, additional, and Gillenwater, Ann M., additional

Published
2021
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4. Trilaciclib prior to chemotherapy reduces the usage of supportive care interventions for chemotherapy‐induced myelosuppression in patients with small cell lung cancer: Pooled analysis of three randomized phase 2 trials

Author

Ferrarotto, Renata, primary, Anderson, Ian, additional, Medgyasszay, Balazs, additional, García‐Campelo, Maria Rosario, additional, Edenfield, William, additional, Feinstein, Trevor M., additional, Johnson, Jennifer M., additional, Kalmadi, Sujith, additional, Lammers, Philip E., additional, Sanchez‐Hernandez, Alfredo, additional, Pritchett, Yili, additional, Morris, Shannon R., additional, Malik, Rajesh K., additional, and Csőszi, Tibor, additional

Published
2021
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9. Counseling in Ireland

Author

O'Morain, Padraig, primary, McAuliffe, Garrett J., additional, Conroy, Kayte, additional, Johnson, Jennifer M., additional, and Michel, Rebecca E., additional

Published
2012
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12. Effect of preoperative programmed death-1 or programmed death ligand-1 immune check point inhibition on complications after surgery for primary head and neck cancer.

Author

Philips R, Alnemri A, Amin D, Patel J, Topf MC, Johnson JM, BarAd V, Axelrod R, Argiris A, Fundakowski C, Luginbuhl AJ, Cognetti DM, and Curry JM

Subjects
Humans, Squamous Cell Carcinoma of Head and Neck drug therapy, Squamous Cell Carcinoma of Head and Neck surgery, Ligands, Retrospective Studies, Head and Neck Neoplasms drug therapy, Head and Neck Neoplasms surgery, Plastic Surgery Procedures
Abstract

Background: There is sparse literature on the effect of preoperative immunotherapy on complications after surgery for primary head and neck squamous cell carcinoma (HNSCC). The objectives are to compare complication rates in patients receiving surgery with and without neoadjuvant immune checkpoint inhibitors (nICI) for primary HNSCC and to evaluate factors associated with increased odds of surgical complications., Methods: A retrospective review of patients who underwent ablation and free flap reconstruction or transoral robotic surgery (TORS) for primary HNSCC between 2017-2021 was conducted. Complications were compared between patients who underwent surgery with or without nICI before and after propensity score matching. Regression analysis to estimate odds ratios was performed., Results: A total of 463 patients met inclusion criteria. Free flap reconstruction constituted 28.9% of patients and TORS constituted 71.1% of patients. nICI was administered in 83 of 463 (17.9%) patients. There was no statistically significant difference in surgical, medical, or overall complications between patients receiving surgery with or without nICI. In the unmatched cohort, multivariable model identified non-White race, former/current smoking history, free flap surgery, and perineural invasion as factors significantly associated with increased complications. In the matched cohort, multivariable model identified advanced age and free flap surgery as factors significantly associated with increased complications., Plain Language Summary: It is safe to give immunotherapy before major surgery in patients who have head and neck cancer. Advanced age, non-White race, current/former smoking, free flap surgery, and perineural invasion may be associated with increased the odds of surgical complications., (© 2023 The Authors. Cancer published by Wiley Periodicals LLC on behalf of American Cancer Society.)

Published
2024
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