1. Five-Year Experience With Mini-Volume Priming in Infants ≤5 kg: Safety of Significantly Smaller Transfusion Volumes
- Author
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Yong Jin Kim, Woong-Han Kim, Jae Hee Cho, Jeong Ryul Lee, Jinhae Nam, and Hyoung Woo Chang
- Subjects
Body surface area ,medicine.medical_specialty ,Blood transfusion ,medicine.diagnostic_test ,business.industry ,medicine.medical_treatment ,Biomedical Engineering ,Medicine (miscellaneous) ,Bioengineering ,Retrospective cohort study ,General Medicine ,Hematocrit ,Surgery ,law.invention ,Cardiac surgery ,Biomaterials ,law ,Anesthesia ,medicine ,Cardiopulmonary bypass ,Risk factor ,business ,Priming (psychology) - Abstract
Reducing the cardiopulmonary bypass (CPB) priming volume in congenital cardiac surgery is important because it is associated with fewer transfusions. This retrospective study was designed to compare safety and transfusion volumes between the mini-volume priming (MP) and conventional priming (CP) methods. Between 2007 and 2012, congenital heart surgery using CPB was performed on 480 infants (≤5 kg): the MP method was used in 331 infants (MP group, 69.0%), and the CP method was used in 149 infants (CP group, 31.0%). In the MP group, narrow-caliber (3/16″) tubing was used, and the pump heads were vertically aligned to shorten the tubing lengths. The smallest possible oxygenators and hemofilters were used, and vacuum drainage was applied. Ultrafiltration was vigorously applied during CPB to avoid excessive hemodilution. The mean age and body weight of the patients were 48 ± 41 (0-306) days and 3.8 ± 0.8 (1.3-5.0) kg, respectively. The total priming and transfusion volumes during CPB were lower in the MP group than in the CP group (141 ± 24 mL vs. 292 ± 50 mL, P
- Published
- 2013