Author: "James F. Long" / Publisher: wiley - Searchworks@Jio Institute Digital Library Search Results

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Author: Elijah H. Gold, James A. Bristol, Raymond G. Lovey, and James F. Long
Subjects: Chemistry, Antisecretory agents, General Medicine, Pharmacology
Published: 1982

Author: Shing-Chun Wong, David J. Conn, James A. Bristol, Henry Guzik, M. Steinberg, Andrew T. McPhail, P. J. S. Chiu, Arthur J. Elliott, Daniel M. Solomon, James F. Long, Raymond G. Lovey, Chester Puchalski, James J. Kaminski, Elijah H. Gold, and Martin S. Domalski
Subjects: Chemistry, General Medicine, Pharmacology, Antiulcer agents
Published: 1985

Author: Raymond G. Lovey, Elijah H. Gold, James A. Bristol, Irwin Gross, and James F. Long
Subjects: medicine.drug_class, Thio, Antisecretory agents, General Medicine, Pharmacology, chemistry.chemical_compound, chemistry, Anticholinergic, medicine, Gastric acid, Secretion, Antagonism, Receptor, Histamine
Abstract: A series of 9-[(aminoalkyl)thio]-9H-xanthenes (3-6) and 5-[(aminoalkyl)thio]-5H-[1]benzopyrano[2,3-b]pyridines (7-10) possessing gastric antisecretory activity in the rat and dog is described Many of the compounds possessed good activity in the pylorus-ligated rat and several inhibited histamine-stimulated gastric acid secretion in the dog. The mechanism of acid secretion inhibition is not related to anticholinergic or histamine (H2) receptor antagonism.
Published: 1982

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