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Your search keyword '"Hiraishi H"' showing total 14 results
Start Over Author "Hiraishi H" Publisher wiley
14 results on '"Hiraishi H"'

1. Randomised clinical trial: rabeprazole improves symptoms in patients with functional dyspepsia in Japan

Author

Iwakiri, R., primary, Tominaga, K., additional, Furuta, K., additional, Inamori, M., additional, Furuta, T., additional, Masuyama, H., additional, Kanke, K., additional, Nagahara, A., additional, Haruma, K., additional, Kinoshita, Y., additional, Higuchi, K., additional, Takahashi, S., additional, Kusano, M., additional, Iwakiri, K., additional, Kato, M., additional, Hongo, M., additional, Hiraishi, H., additional, Watanabe, S., additional, Miwa, H., additional, Naito, Y., additional, Fujimoto, K., additional, and Arakawa, T., additional

Published
2013
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13. Enhanced brain signal variability in children with autism spectrum disorder during early childhood.

Author

Takahashi T, Yoshimura Y, Hiraishi H, Hasegawa C, Munesue T, Higashida H, Minabe Y, and Kikuchi M

Subjects
Brain growth & development, Child, Child, Preschool, Female, Humans, Magnetoencephalography methods, Male, Photic Stimulation, Severity of Illness Index, Autism Spectrum Disorder physiopathology, Brain physiopathology, Motion Perception physiology
Abstract

Extensive evidence shows that a core neurobiological mechanism of autism spectrum disorder (ASD) involves aberrant neural connectivity. Recent advances in the investigation of brain signal variability have yielded important information about neural network mechanisms. That information has been applied fruitfully to the assessment of aging and mental disorders. Multiscale entropy (MSE) analysis can characterize the complexity inherent in brain signal dynamics over multiple temporal scales in the dynamics of neural networks. For this investigation, we sought to characterize the magnetoencephalography (MEG) signal variability during free watching of videos without sound using MSE in 43 children with ASD and 72 typically developing controls (TD), emphasizing early childhood to older childhood: a critical period of neural network maturation. Results revealed an age-related increase of brain signal variability in a specific timescale in TD children, whereas atypical age-related alteration was observed in the ASD group. Additionally, enhanced brain signal variability was observed in children with ASD, and was confirmed particularly for younger children. In the ASD group, symptom severity was associated region-specifically and timescale-specifically with reduced brain signal variability. These results agree well with a recently reported theory of increased brain signal variability during development and aberrant neural connectivity in ASD, especially during early childhood. Results of this study suggest that MSE analytic method might serve as a useful approach for characterizing neurophysiological mechanisms of typical-developing and its alterations in ASD through the detection of MEG signal variability at multiple timescales., (© 2015 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.)

Published
2016
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14. The terminal protein of the linear DNA plasmid pGKL2 shares an N-terminal domain of the plasmid-encoded DNA polymerase.

Author

Takeda M, Hiraishi H, Takesako T, Tanase S, and Gunge N

Subjects
Amino Acid Sequence, Molecular Sequence Data, DNA-Directed DNA Polymerase chemistry, Kluyveromyces genetics, Plasmids
Abstract

The 36K protein attached at the 5' end of the linear DNA plasmid pGKL2 from the yeast Kluyveromyces lactis was first purified and characterized. The terminal protein was purified from cells (1 kg wet weight) by ammonium sulphate precipitation and two rounds of centrifugation to equilibrium in CsCl gradients. The pGKL2 was present only in the post-microsomal supernatant. Approximately 10 mg of the purified pGKL2 was recovered and digested with DNase I. The terminal protein (final ca. 0 center dot 8 mg) was homogeneous by electrophoresis and we determined the N-terminal amino acid sequence up to ten residues, showing that it existed in the cryptic N-terminal domain of pGKL2-ORF2 (DNA polymerase) sequence.

Published
1996
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