1. Malignant pleural mesothelioma with lacrimal gland metastasis
- Author
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Robert M. Verdijk, Hanida Hanafi, Dion Paridaens, and Pathology
- Subjects
Pathology ,medicine.medical_specialty ,medicine.medical_treatment ,Lacrimal gland ,Eye neoplasm ,Metastasis ,03 medical and health sciences ,0302 clinical medicine ,Biopsy ,medicine ,Mesothelioma ,Pleural Neoplasm ,neoplasms ,medicine.diagnostic_test ,business.industry ,General Medicine ,respiratory system ,medicine.disease ,respiratory tract diseases ,Radiation therapy ,Ophthalmology ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,030221 ophthalmology & optometry ,business ,Orbit (anatomy) - Abstract
Purpose To describe a rare clinical case of biopsy-proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy. Methods Interventional case report. Results A 55-year-old woman with an untreated malignant biopsy-proven pleural mesothelioma presented with right proptosis, diplopia and hypoglobus. Magnetic resonance imaging showed an aggressive lacrimal gland tumour with bony erosion. A biopsy concluded a diagnosis of metastatic mesothelioma of the lacrimal gland. Her lacrimal and lung tumours showed a marked regression following palliative chemo (carboplatin) and radiation therapy. Conclusions Malignant pleural mesothelioma may metastasize to the orbit, including the lacrimal gland. A combined chemo and radiation therapy may reduce the size of the metastatic and primary tumour.
- Published
- 2016