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3 results on '"Haiqun Xie"'

1. Higher Adiposity Is Associated With Slower Cognitive Decline in Hypertensive Patients: Secondary Analysis of the China Stroke Primary Prevention Trial

Author

Jun Zhang, Genfu Tang, Haiqun Xie, Binyan Wang, Mingli He, Jia Fu, Xiuli Shi, Chengguo Zhang, Yong Huo, Xiping Xu, and Kai Wang

Subjects
adiposity, body mass index, cognitive decline, hypertension, waist circumference, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

BackgroundObesity is a risk factor for many diseases. However, the potential association between adiposity and cognitive decline in hypertensive patients is inconclusive. We performed a secondary data analysis of the CSPPT (China Stroke Primary Prevention Trial) to examine whether adiposity is correlated with longitudinal cognitive performance in hypertensive adults. Methods and ResultsThe analysis included 16 791 patients in the CSPPT who received at least 2 cognitive assessments by the Mini‐Mental State Examination (MMSE) during the follow‐up (median, 4.5 years; interquartile range, 4.2–4.8 years). Outcomes included changes in MMSE scores and cognitive impairment (defined as MMSE score less than education‐specific cutoff point). A marked reduction in MMSE scores at the final (compared with at the 1‐year) follow‐up was apparent in both men (n=4838; mean [SD] score, 0.41 [3.62]) and women (n=7190; mean [SD] score, 1.07 [4.61]; both P

Published
2017
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2. The cost of Alzheimer's disease in China and re‐estimation of costs worldwide

Author

Lan Chu, Shanshan Yang, Yue Han, Aihong Zhou, Yifeng Du, Lu Shen, Xiumei Zuo, Enyan Yu, Jianping Jia, Jintao Zhang, Serge Gauthier, Yong Ji, Changbiao Chu, Liyuan Huang, Kunnan Zhang, Fang Li, Lan Tan, Longfei Jia, Shuoqi Chen, Wei Qin, Jihui Lv, Lina Zhao, Chunkui Zhou, Qi Wang, Haiqun Xie, Jiewen Zhang, Hongmei Jin, Ying Han, Lu Shi, Peiyuan Lv, Cuibai Wei, Fen Wang, Yang Lv, Junjian Zhang, Boyan Fang, Benyan Luo, Dan Li, Muni Tang, Min Gong, Jinbiao Zhang, Furu Liang, Qihao Guo, Yan-Jiang Wang, Yi Tang, Dantao Peng, Fangyu Li, Qiumin Qu, Hui Xu, and Liyong Wu

Subjects
Male, 0301 basic medicine, China, Epidemiology, Cross-sectional study, Total cost, Disease, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Cost of Illness, Developmental Neuroscience, Alzheimer Disease, Environmental health, medicine, Humans, Dementia, Socioeconomic status, Aged, Aged, 80 and over, Estimation, Health Policy, Health Care Costs, Middle Aged, medicine.disease, Psychiatry and Mental health, Cross-Sectional Studies, 030104 developmental biology, Socioeconomic Factors, Female, Observational study, Neurology (clinical), Business, Geriatrics and Gerontology, 030217 neurology & neurosurgery, Forecasting
Abstract

Introduction The socioeconomic costs of Alzheimer's disease (AD) in China and its impact on global economic burden remain uncertain. Methods We collected data from 3098 patients with AD in 81 representative centers across China and estimated AD costs for individual patient and total patients in China in 2015. Based on this data, we re-estimated the worldwide costs of AD. Results The annual socioeconomic cost per patient was US $19,144.36, and total costs were US $167.74 billion in 2015. The annual total costs are predicted to reach US $507.49 billion in 2030 and US $1.89 trillion in 2050. Based on our results, the global estimates of costs for dementia were US $957.56 billion in 2015, and will be US $2.54 trillion in 2030, and US $9.12 trillion in 2050, much more than the predictions by the World Alzheimer Report 2015. Discussion China bears a heavy burden of AD costs, which greatly change the estimates of AD cost worldwide.

Published
2018

3. P3-238: IMR-ASSAYED PLASMA Aβ42 AND T-TAU CLASSIFIED MILD COGNITIVE IMPAIRED AND MILD ALZHEIMER'S DISEASE SUBJECTS WITH HIGH ACCURACIES IN A MULTI-COUNTRY CROSS-SECTIONAL STUDY

Author

Sui-Hing Yan, Akitoshi Takeda, Pei Ning Wang, Lih-Fen Lue, Ming-Jang Chiu, Ming-Chyi Pai, Ta-Fu Chen, Shieh-Yueh Yang, Yoshiaki Itoh, Satoru Morimoto, Chau-Chung Wu, Chaur-Jong Hu, Hiroyuki Hatsuta, Jun Liu, Jian-shing Jeng, Marwan N. Sabbagh, Kaj Blennow, Li-Kai Huang, Wei-Che Lin, and Haiqun Xie

Subjects
medicine.medical_specialty, Epidemiology, Cross-sectional study, business.industry, Health Policy, Cognition, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, Neurology (clinical), Geriatrics and Gerontology, business, Multi country
Published
2019

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