47 results on '"Ghiso, Jorge"'
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2. Enhanced Brain Retention of Aβ4‐x Proteoforms and its Contribution to Amyloid Deposits in Alzheimer’s Disease
3. Alzheimer‐like pathology in trisomy 21 cerebral organoids amenable to pharmacological inhibition reveals BACE2 as a gene‐dose‐sensitive AD‐suppressor in human brain
4. Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis
5. Pharmacologic Modulation of Mitochondrial Pathogenic Changes in Alzheimer’s Aβ‐Challenged Neurons
6. N‐ and C‐Terminal Alzheimer’s Aβ Heterogeneity Modulates the Balance Between Brain Clearance and Amyloid Formation
7. [P2-158]: IS THE PRESUBICULUM PROTECTED FROM NEURODEGENERATIVE CHANGES? A PATHOLOGICAL AND BIOCHEMICAL INVESTIGATION
8. P1-093: Characterization of Novel Bioavailable Bioactive Polyphenolic Compounds for Pharmacological Preservation of Blood Brain Barrier Function in Alzheimer’s Disease
9. P4‐209: Methazolamide protects neuronal and glial cells from amyloid toxicity in vitro and in vivo via mitochondria‐mediated mechanisms
10. O2-12-01: MITOCHONDRIA AND DEATH RECEPTORS: KEY TARGETS FOR AMYLOID TOXICITY IN THE CEREBRAL VASCULATURE
11. P1-109: MITOCHONDRIAL DYSFUNCTION INDUCED BY A POSTTRANSLATIONALLY MODIFIED AMYLOID LINKED TO A FAMILIAL MUTATION IN AN ALTERNATIVE MODEL OF NEURODEGENERATION
12. Amyloid beta oligomers trigger death receptors‐mediated apoptosis in cerebral endothelial cells
13. Inherited Amyloidoses and Neurodegeneration: Familial British Dementia and Familial Danish Dementia
14. A Strategy for Designing a Peptide Probe for Detection of β-Amyloid Oligomers
15. P1-237: Fibrillogenesis and toxicity of Iowa-Aβ amyloid is primarily driven by the D23N mutation
16. O4‐05‐05: Modeling familial danish dementia: Implications for the amyloid hypothesis of Alzheimer's disease
17. P1-195: Involvement of the choroid plexus in the clearance of Aβ
18. P1‐038: Pyroglutamate formation at the N‐termini of ABri molecules in familial British dementia occurs at the sites of deposition and is not restricted to the central nervous system
19. P2-215: Molecular analysis of apoptotic pathways induced by amyloid-β variants in cerebral vascular cells
20. P3-212: Catabolism of Alzheimer's amyloid-β: Implications for brain clearance and plaque deposition
21. Isolation and Biochemical Characterization of Amyloid Plaques and Paired Helical Filaments
22. BRI2 as a central protein involved in neurodegeneration
23. P1-076: Modeling Familial Danish dementia
24. P2‐294: Microarray profiling reveals autoantibody reactivities against abnormal amyloid peptide conformations decline with age and in Alzheimer's disease
25. P1-072: Transgenic mouse models of familial British and Danish dementias
26. P4-078: Matrix metalloproteases and Aβ clearance
27. P4-083: Amyloid ion channels: A common structural link for protein-misfolding disease pathogenesis?
28. P2-005: Patterns of Aβ accumulation in Alzheimer's and aged primate brain
29. P3–354: Post–translational modifications in Aβ and non–Aβ cerebral amyloidosis
30. P4-060: Oligomeric assemblies of the Aβ Dutch mutant induce the formation of nucleosomes in primary human cerebral endothelial cells
31. O2-03-06: BRI2 modulates amyloid precursor protein processing and inhibits aβ generation
32. Sporadic and Familial Cerebral Amyloid Angiopathies
33. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
34. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
35. Isoform-Specific Effects of Apolipoproteins E2, E3, and E4 on Cerebral Capillary Sequestration and Blood-Brain Barrier Transport of Circulating Alzheimer's Amyloid β
36. Tumoral non-amyloidotic monoclonal immunoglobulin light chain deposits (‘aggregoma’): presenting feature of B-cell dyscrasia in three cases with immunohistochemical and biochemical analyses
37. Distinct Secretases, a Cysteine Protease and a Serine Protease, Generate the C Termini of Amyloid β-Proteins Aβ1-40 and Aβ1-42, Respectively
38. Induction of NADPH cytochrome P450 reductase by the Alzheimer β-protein. Amyloid as a ‘foreign body’
39. Inclusion body myositis, muscle blood vessel and cardiac amyloidosis, and transthyretin Val122Ile allele
40. Apolipoprotein J (clusterin) and Alzheimer's disease
41. pH-dependent fibrillogenesis of a VκIII Bence Jones protein
42. Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome
43. Lipoprotein‐free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome
44. Cerebrovascular Accumulation and Increased Blood‐Brain Barrier Permeability to Circulating Alzheimer's Amyloid β Peptide in Aged Squirrel Monkey with Cerebral Amyloid Angiopathy
45. Alzheimer's soluble amyloid β is a normal component of human urine
46. Alzheimer's presenilin 1 gene expression in platelets and megakaryocytes
47. Cerebrospinal fluid inhibits Alzheimer ?-amyloid fibril formation in vitro
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