3 results on '"Fernanda Maria Policarpo Tonelli"'
Search Results
2. Aquatic Contamination : Tolerance and Bioremediation
- Author
-
Rouf Ahmad Bhat, Gowhar Hamid Dar, Fernanda Maria Policarpo Tonelli, Saima Hamid, Rouf Ahmad Bhat, Gowhar Hamid Dar, Fernanda Maria Policarpo Tonelli, and Saima Hamid
- Subjects
- Water--Pollution, Bioremediation
- Abstract
Aquatic Contamination Authoritative resource presenting techniques and technologies to sustainably neutralize environmental contamination in aquatic plants, microorganisms, and more Two thirds of the Earth is covered with aquatic habitats that play a key role in stabilizing the global environment and providing a wide variety of services to increasing human needs. Nevertheless, anthropogenic activities are rapidly destroying the quality of both fresh and marine waters globally, due to excessive use of chemicals, fertilizers and pollution from suburban and industrial areas eventually making their way into the aquatic world. Aquatic Contamination: Tolerance and Bioremediation presents the broader spectrum of biological applicability of microbes with better understanding of cellular mechanisms for remediation of aquatic contaminants. The book also focuses on practices involved in molecular and genetic approaches, necessary to achieve targets of bioremediation and phytoremediation to solve global water contamination problems. Such approaches pave the way for the utilization of biological assets to design new, efficient, and environmentally sound remediation strategies by inculcating genomic techniques at cellular and molecular levels with model assessment. Aquatic Contamination provides a comprehensive background for readers interested in all perspectives of the contamination of aquatic environs. It covers various research aspects which are being carried out globally to understand simulation models in the assessment of xenobiotics, role of genomics, transgenic plants, and microbial enzymes for degradation and removal of toxic substances in aquatic environs. Key features include: Extensive coverage of interactions between plants, metals and microbes including the influence of biotic and abiotic factors Comprehensive discussion of the details of molecular mechanisms from assimilation to detoxification levels Exploration of the enzymatic approaches of potential plants acting as hyper-accumulators for contaminants in aquatic environs Details of sustainable tools such as transgenic plants for the manipulation of important functional microbial genes to achieve higher certainty of bioremediation Details of advances in tools and models like micro-arrays and simulation models for the complete assessment of xenobiotic compounds from cellular to degradation hierarchies Aquatic Contamination: Tolerance and Bioremediation will be substantially helpful to environmentalists, microbiologists, biotechnologists and scientists, providing essential information on various modern technologies for the remediation of contaminants in aquatic ecosystems.
- Published
- 2023
3. Human adult stem cells from diverse origins: An overview from multiparametric immunophenotyping to clinical applications
- Author
-
Bruna R. Sousa, Pritesh Lalwani, Rodrigo R. Resende, Ricardo Parreira, Alexandre Hiroaki Kihara, Emerson A. Fonseca, Anderson K. Santos, Fernanda Maria Policarpo Tonelli, Maria Jimena Amaya, Henning Ulrich, Samyra M.S.N. Lacerda, and Katia N. Gomes
- Subjects
Histology ,Mesenchymal stem cell ,Clinical uses of mesenchymal stem cells ,Amniotic stem cells ,Cell Biology ,Biology ,Pathology and Forensic Medicine ,Amniotic epithelial cells ,Immunology ,Cancer research ,Stem cell ,Induced pluripotent stem cell ,Adult stem cell ,Stem cell transplantation for articular cartilage repair - Abstract
Stem cells are known for their capacity to self-renew and differentiate into at least one specialized cell type. Mesenchymal stem cells (MSCs) were isolated initially from bone marrow but are now known to exist in all vascularized organ or tissue in adults. MSCs are particularly relevant for therapy due to their simplicity of isolation and cultivation. The International Society for Cellular Therapy (ISCT) has proposed a set of standards to define hMSCs for laboratory investigations and preclinical studies: adherence to plastic in standard culture conditions; in vitro differentiation into osteoblasts, adipocytes, and chondroblasts; specific surface antigen expression in which ≥95% of the cells express the antigens recognized by CD105, CD73, and CD90, with the same cells lacking (≤2% positive) the antigens CD45, CD34, CD14 or CD11b, CD79a or CD19, and HLA-DR. In this review we will take an historical overview of how umbilical cord blood, bone marrow, adipose-derived, placental and amniotic fluid, and menstrual blood stem cells, the major sources of human MSC, can be obtained, identified and how they are being used in clinical trials to cure and treat a very broad range of conditions, including heart, hepatic, and neurodegenerative diseases. An overview of protocols for differentiation into hepatocytes, cardiomyocytes, neuronal, adipose, chondrocytes, and osteoblast cells are highlighted. We also discuss a new source of stem cells, induced pluripotent stem cells (iPS cells) and some pathways, which are common to MSCs in maintaining their pluripotent state.
- Published
- 2013
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.