1. Contextual and historical factors for increased levels of anxiety and depression in patients with head and neck cancer: A prospective longitudinal study
- Author
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Xun Zhang, Melissa Henry, Fabienne Fuehrmann, Martin J. Black, Keith Richardson, Zeev Rosberger, Karen M. Kost, Gabrielle Chartier, Michael P. Hier, Alex Mlynarek, Saul Frenkiel, Christina MacDonald, and Anthony Zeitouni
- Subjects
Adult ,Male ,Longitudinal study ,Anxiety ,Life Change Events ,03 medical and health sciences ,0302 clinical medicine ,Interview, Psychological ,medicine ,Humans ,Longitudinal Studies ,Prospective Studies ,Medical diagnosis ,030223 otorhinolaryngology ,Depression (differential diagnoses) ,Aged ,Aged, 80 and over ,Neuroticism ,Depressive Disorder, Major ,Depression ,business.industry ,Medical record ,Middle Aged ,medicine.disease ,Anxiety Disorders ,Otorhinolaryngology ,Head and Neck Neoplasms ,030220 oncology & carcinogenesis ,Major depressive disorder ,Female ,medicine.symptom ,business ,Stress, Psychological ,Anxiety disorder ,Clinical psychology - Abstract
Background This study aimed at examining predictors of clinical anxiety and depressive symptoms in patients with head and neck cancer (HNC) at 3, 6, and 12 months post-diagnosis, with a particular interest in contextual and historical factors. Methods Prospective longitudinal study of 219 consecutive patients newly diagnosed with a first occurrence of primary HNC, including psychometric measures, Structured Clinical Interview for DSM-IV Diagnoses (SCID), and medical chart reviews. Results Point prevalence of clinical anxiety symptoms (Hospital Anxiety and Depression Scale-Anxiety subscale) was 32.0%, 21.9%, 12.1%, and 12.6% at baseline, 3, 6, and 12 months; and clinical depressive symptoms on the Depression Subscale was 19.4%, 21.9%, 13.5%, and 9.2%, respectively. Predictors of anxiety and depressive symptoms included upon diagnosis SCID major depressive or anxiety disorder, stressful life events in previous year, neuroticism, and levels of anxiety and depressive symptoms upon cancer diagnosis. Conclusions This study emphasizes the predictive contribution of broader personal contextual and historical factors that increase psychological vulnerability in HNC and merit consideration.
- Published
- 2019
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