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2. Relationship between platelet count and platelet width distribution and serum uric acid 1 concentrations in patients with untreated essential hypertension

Author

Tayefi, Maryam, Hassanian, Seyed Mahdi, Maftouh, Mona, Moohebati, Mohsen, Bahrami, Afsane, Parizadeh, Seyed MohammadReza, Mahdizadeh, Adeleh, Ghazizadeh, Hamideh, Bazeli, Javad, Heidari-Bakavoli, Alireza, Kianifar, Hamidreza, Mohammadzadeh, Elham, Rahmani, Farzad, Esmaeili, Habibollah, Ebrahimi, Mahmoud, Azarpazhooh, Mahmoud Reza, Nematy, Mohsen, Safarian, Mohammad, Ferns, Gordon, Avan, Amir, and Ghayour-Mobarhan, Majid

Abstract

Hematological parameters have emerged as independent determinants of high serum concentrations of uric-acid and predictive-factors in the evaluation of the total cardiovascular-risk in patients with essential-hypertensive. Here we have investigated the possible relationships between hematological-factors and serum uric-acid levels in hypertensive-patients recruited as part of Mashhad-Stroke and Heart-Atherosclerotic-Disorders cohort study. Two-thousand three-hundred and thirty four hypertensive individuals were recruited from this cohort and these were divided into two groups; those with either high or low serum uric acid concentrations. Demographic, biochemical and hematological characteristics of population were evaluated in all the subjects. Logistic-regression-analysis was performed to determine the association of hematological-parameters with hypertension. Of the 2334 hypertensive-subjects, 290 cases had low uric-acid, and 2044 had high serum uric acid concentrations. Compared with the low uric acid group, the patients with high serum uric acid, had higher values for several hematological parameters, whilst platelet counts (PLT) were lower. Multiple linear regression analysis showed that PLT and serum hs-CRP were correlated with serum uric acid level. Stepwise multiple logistic regression model confirmed that PDW and gender were independent determinant of a high serum uric acid. PDW and PLT appear to be independently associated with serum uric acid level in patients with hypertension.

Published
2018

3. Relationship between platelet count and platelet width distribution and serum uric acid concentrations in patients with untreated essential hypertension

Author

Tayefi, Maryam, primary, Hassanian, Seyed Mahdi, additional, Maftouh, Mona, additional, Moohebati, Mohsen, additional, Bahrami, Afsane, additional, Parizadeh, Seyed MohammadReza, additional, Mahdizadeh, Adeleh, additional, Ghazizadeh, Hamideh, additional, Bazeli, Javad, additional, Heidari‐Bakavoli, Alireza, additional, Kianifar, Hamidreza, additional, Mohammadzadeh, Elham, additional, Rahmani, Farzad, additional, Esmaeili, Habibollah, additional, Ebrahimi, Mahmoud, additional, Azarpazhooh, Mahmoud Reza, additional, Nematy, Mohsen, additional, Safarian, Mohammad, additional, Ferns, Gordon A, additional, Avan, Amir, additional, and Ghayour‐Mobarhan, Majid, additional

Published
2018
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4. Prevalence of combined and noncombined dyslipidemia in an Iranian population

Author

Darroudi, Susan, primary, Saberi-Karimian, Maryam, additional, Tayefi, Maryam, additional, Arekhi, Soheil, additional, Motamedzadeh Torghabeh, Ali, additional, Seyedzadeh Sani, Seyed Mohammad Reza, additional, Moohebati, Mohsen, additional, Heidari-Bakavoli, Alireza, additional, Ebrahimi, Mahmoud, additional, Azarpajouh, Mahmoud Reza, additional, Safarian, Mohammad, additional, A. Ferns, Gordon, additional, Esmaeili, Habibollah, additional, Parizadeh, Mohammad Reza, additional, Mokhber, Naghme, additional, Mahdizadeh, Adeleh, additional, Mahmoudi, Ali Asghar, additional, Sahebkar, Amir Hossein, additional, and Ghayour-Mobarhan, Majid, additional

Published
2018
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5. Genetic and epigenetic factors influencing vitamin D status

Author

Bahrami, Afsane, primary, Sadeghnia, Hamid Reza, additional, Tabatabaeizadeh, Seyed‐Amir, additional, Bahrami‐Taghanaki, Hamidreza, additional, Behboodi, Negin, additional, Esmaeili, Habibollah, additional, Ferns, Gordon A., additional, Mobarhan, Majid Ghayour, additional, and Avan, Amir, additional

Published
2017
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6. The Effects of Curcumin and Curcumin-Phospholipid Complex on the Serum Pro-oxidant-Antioxidant Balance in Subjects with Metabolic Syndrome

Author

Ghazimoradi, Maryam, primary, Saberi-Karimian, Maryam, additional, Mohammadi, Farzane, additional, Sahebkar, Amirhossein, additional, Tavallaie, Shima, additional, Safarian, Hamideh, additional, Ferns, Gordon A., additional, Ghayour-Mobarhan, Majid, additional, Moohebati, Mohsen, additional, Esmaeili, Habibollah, additional, and Ahmadinejad, Malihe, additional

Published
2017
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7. High Dose Supplementation of Vitamin D Affects Measures of Systemic Inflammation: Reductions in High Sensitivity C‐Reactive Protein Level and Neutrophil to Lymphocyte Ratio (NLR) Distribution

Author

Tabatabaeizadeh, Seyed‐Amir, primary, Avan, Amir, additional, Bahrami, Afsane, additional, Khodashenas, Ezzat, additional, Esmaeili, Habibollah, additional, Ferns, Gordon A., additional, Abdizadeh, Mojtaba Fattahi, additional, and Ghayour‐Mobarhan, Majid, additional

Published
2017
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8. Association of hematocrit with blood pressure and hypertension

Author

Emamian, Marzieh, primary, Hasanian, Seyed Mahdi, additional, Tayefi, Maryam, additional, Bijari, Moniba, additional, Movahedian far, Faeze, additional, Shafiee, Mojtaba, additional, Avan, Amir, additional, Heidari-Bakavoli, Alireza, additional, Moohebati, Mohsen, additional, Ebrahimi, Mahmoud, additional, Darroudi, Sousan, additional, Zamani, Parvin, additional, Azarpazhooh, Mahmoud Reza, additional, Nematy, Mohsen, additional, Safarian, Mohammad, additional, Ferns, Gordon A., additional, Esmaeili, Habibollah, additional, Parizadeh, Mohammad Reza, additional, and Ghayour-Mobarhan, Majid, additional

Published
2017
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