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4 results on '"Emin Murat Akbas"'

1. Multisystemic Side Effects of an Indispensable Old Drug: A Case Report of Chronic Lithium Use (A Patient with Multiple Side Effects of Lithium)

Author

Levent Demirtas, Emin Murat Akbas, Husnu Degirmenci, Ali Gurel, and Eren Duzgun

Subjects
Medicine
Abstract

Presented here is a case of long-term lithium use, with multiple emerging lithium-associated side effects. An 82-year-old woman was brought into the emergency department because of loss of consciousness. According to the physical examination and laboratory analyses, patient was diagnosed with lithium-associated hypercalcemia, hyperparathyroidism, nephrogenic diabetes insipidus (NDI), symptomatic sinus bradycardia, and thyroid dysfunction. In the literature, there is a limited number of case reports with lithium induced multiple clinical conditions. Multiple clinical manifestations due to the side effects of chronic lithium use might be seen. Health care professionals should keep in mind that lithium-related side effects might trigger or exacerbate each other. To avoid toxicity, close follow-up and clinical supervision are important for the early diagnosis and treatment of these side effects, due to the narrow therapeutic index and obscure clinical signs and symptoms of toxicity.

Published
2015
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3. The relationship between neutrophil-to-lymphocyte ratio and vascular calcification in end-stage renal disease patients

Author

Kultigin Turkmen, Fatih Mehmet Erdur, Emin Murat Akbas, Halil Zeki Tonbul, Adalet Ozcicek, and Fatih Ozcicek

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, fungi, Inflammation, Hematology, Disease, Stepwise regression, medicine.disease, End stage renal disease, Surgery, Peritoneal dialysis, Nephrology, Internal medicine, cardiovascular system, medicine, Cardiology, cardiovascular diseases, Hemodialysis, Neutrophil to lymphocyte ratio, medicine.symptom, business, Calcification
Abstract

Chronic inflammation was found to be correlated with coronary (CAC) and thoracic peri-aortic calcification (TAC) in end-stage renal disease (ESRD) patients. Neutrophil-to-lymphocyte ratio (NLR) was introduced as a potential marker to determine inflammation in cardiac and noncardiac disorders. Data regarding NLR and its association with TAC and CAC are lacking. We aimed to determine the relationship between NLR and vascular calcification in ESRD patients. This was a cross-sectional study involving 56 ESRD patients (22 females, 34 males; mean age, 49.9 ± 14.2 years) receiving peritoneal dialysis or hemodialysis for ≥6 months in the Dialysis Unit of Necmettin Erbakan University. TAC and CAC scores were measured by using an electrocardiogram-gated 64-multidetector computed tomography. NLR was calculated as the ratio of the neutrophils and lymphocytes. There was a statistically significant correlation between NLR, TACS and CACS in ESRD patients (r = 0.43, P = 0.001 and r = 0.30, P = 0.02, respectively). The stepwise linear regression analysis revealed that age, as well as NLR were independent predictors of TACS. However, increased age was the only independent predictor of CACS according to linear regression analysis. Simple calculation of NLR can predict vascular calcification in ESRD patients.

Published
2013

4. Platelet‐to‐lymphocyte ratio better predicts inflammation than neutrophil‐to‐lymphocyte ratio in end‐stage renal disease patients

Author

Levent Demirtas, Kultigin Turkmen, Adalet Ozcicek, Suleyman Turk, Emin Murat Akbas, H. Zeki Tonbul, Fatih Mehmet Erdur, Fatih Ozcicek, and Aysu Ozbicer

Subjects
medicine.medical_specialty, education.field_of_study, business.industry, Lymphocyte, medicine.medical_treatment, fungi, Population, Interleukin, Inflammation, Hematology, Gastroenterology, Peritoneal dialysis, End stage renal disease, body regions, medicine.anatomical_structure, Nephrology, Internal medicine, Immunology, medicine, Hemodialysis, medicine.symptom, Neutrophil to lymphocyte ratio, business, education
Abstract

Neutrophil-to-lymphocyte ratio (NLR) was introduced as a potential marker to determine inflammation in end-stage renal disease (ESRD) patients. Recently, platelet-to-lymphocyte ratio (PLR) and NLR were found to positively correlated with inflammatory markers including tumor necrosis factor-α (TNF-α) and interleukin (IL)-6 in cardiac and noncardiac patients. Data regarding PLR and its association with inflammation are lacking in hemodialysis (HD) and peritoneal dialysis (PD) patients. Hence, we aimed to determine the relationship between PLR, NLR, and inflammation in ESRD patients. This was a cross-sectional study involving 62 ESRD patients (29 females, 33 males; mean age, 49.6 ± 14.6 years) receiving PD or HD for ≥6 months in the Dialysis Unit of Necmettin Erbakan University. PLR, NLR, C-reactive protein, TNF-α, IL-6 levels were measured. PLR, NLR, serum high sensitive C-reactive protein, IL-6, and TNF-α levels were significantly higher in PD patients when compared with HD patients. ESRD patients with PLR ≥ 140 had significantly higher NLR, IL-6, and TNF-α levels when compared to patients with PLR

Published
2013

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