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4 results on '"Educational and Family Studies"'

1. A Novel Approach to Investigate the Impact of Mindset and Physiology on the Choice to Invest Effort During an Arithmetic Task

Author

Smiddy Nieuwenhuis, Tieme W. P. Janssen, Denise J. van der Mee, Farah A. Rahman, Martijn Meeter, Nienke M. van Atteveldt, Clinical Developmental Psychology, IBBA, LEARN! - Educational neuroscience, learning and development, APH - Mental Health, APH - Personalized Medicine, Educational and Family Studies, and LEARN! - Learning sciences

Subjects
Cognitive Neuroscience, Developmental and Educational Psychology, Experimental and Cognitive Psychology, Education
Abstract

Growth mindset, the belief that personal attributes such as intelligence are malleable, has previously been related to more effort investment. Here, we investigated how undergraduates' mindset (N = 114) relates to the choice to invest effort during an arithmetic task, indexed by whether they make low vs. high effort-related choices. Social cognitive theory suggests that past performance experiences (mastery vs. failure) and physiological state are important sources for competence self-evaluations. Therefore, in addition to mindset, we also investigated how effort-related choices are influenced more dynamically, by failures and physiological responses during the task. Growth mindset and physiological effort mobilization did not predict effort-related choices but making mistakes did predict lower effort choices in the subsequent round. This study further supports the importance of mastery experiences for effort investment and provides a novel approach for integrating different levels of influence on effort-related choices during an educationally-relevant task.

Published
2023

2. Cortical thickness across the lifespan

Author

Simon E. Fisher, Eveline A. Crone, Dominik Grotegerd, Jilly Naaijen, Anders M. Dale, Sean N. Hatton, Ramona Baur-Streubel, Anthony A. James, Daniel Brandeis, Andrew J. Kalnin, Andreas Reif, Hans-Jörgen Grabe, Pieter J. Hoekstra, Lars Nyberg, Fleur M. Howells, Moji Aghajani, Randy L. Buckner, Daniel A. Rinker, Steven G. Potkin, Dennis van 't Ent, Rachel M. Brouwer, Sophia Frangou, Yang Wang, Nhat Trung Doan, Theodore D. Satterthwaite, Christine Lochner, Geraldo F. Busatto, Lars T. Westlye, Lara M. Wierenga, Calhoun Vd, Henry Brodaty, Carles Soriano-Mas, Annette Conzelmann, Christian K. Tamnes, Julian N. Trollor, Nicholas G. Martin, Neeltje E.M. van Haren, René S. Kahn, Irina Lebedeva, Philip Asherson, Suzanne C. Swagerman, John A. Joska, Theophilus N. Akudjedu, Kang Sim, Lachlan T. Strike, Patricia Gruner, Brenna C. McDonald, Thomas Frodl, Edith Pomarol-Clotet, Víctor Ortiz-García de la Foz, Margaret J. Wright, Norbert Hosten, Jean-Paul Fouche, Bernd Weber, Salvador Sarró, Wei Wen, Dag Alnæs, Greig I. de Zubicaray, Iris E. C. Sommer, Marise W. J. Machielsen, Knut Schnell, Dara M. Cannon, Paola Fuentes-Claramonte, Josiane Bourque, Andreas Meyer-Lindenberg, Anton Albajes-Eizagirre, Sarah Hohmann, Erin W. Dickie, Theo G.M. van Erp, Micael Andersson, Paul Pauli, Thomas Espeseth, Heather C. Whalley, Victoria Chubar, Ruben C. Gur, Tomohiro Nakao, Xavier Caseras, Alessandro Bertolino, Ignacio Martínez-Zalacaín, Katharina Wittfeld, Erick J. Canales-Rodríguez, David C. Glahn, Neda Jahanshad, Jiyang Jiang, Katie L. McMahon, Stefan Borgwardt, Erlend S. Dørum, Jaap Oosterlaan, Won Hee Lee, Alan Breier, Steven Williams, Aristotle N. Voineskos, Bernard Mazoyer, Jordan W. Smoller, Nancy C. Andreasen, Ilya M. Veer, Tiffany M. Chaim-Avancini, Sophie Maingault, Paul M. Thompson, Eco J. C. de Geus, Luisa Lázaro, Giulio Pergola, Efstathios Papachristou, Beng-Choon Ho, David Mataix-Cols, Esther Walton, Ben J. Harrison, Dirk J. Heslenfeld, Pablo Najt, Helena Fatouros-Bergman, Derrek P. Hibar, Gunter Schumann, Raymond Salvador, Lieuwe de Haan, Henry Völzke, Joaquim Radua, Henk Temmingh, Lianne Schmaal, Martine Hoogman, Daniel H. Wolf, Georg C. Ziegler, Marieke Klein, Barbara Franke, Erik G. Jönsson, Laura Koenders, Stefan Ehrlich, Oliver Gruber, Ingrid Agartz, Kun Yang, Ryota Kanai, Sarah Baumeister, Colm McDonald, Annabella Di Giorgio, Amanda Worker, Anne Uhlmann, Marcus V. Zanetti, Danai Dima, Matthew D. Sacchet, Sarah E. Medland, Aurora Bonvino, Benedicto Crespo-Facorro, Jan Egil Nordvik, Joshua L. Roffman, Yannis Paloyelis, Jessica A. Turner, T. P. Klyushnik, Christopher G. Davey, Rachel E. Gur, Ian B. Hickie, Christopher R.K. Ching, Jonna Kuntsi, Tobias Banaschewski, Chaim Huyser, Amirhossein Modabbernia, John D. West, Fabrice Crivello, Núria Bargalló, Patricia J. Conrod, Nic J.A. van der Wee, Mauricio H. Serpa, Thomas H. Wassink, Kathryn I. Alpert, Dick J. Veltman, Andrew J. Saykin, Genevieve McPhilemy, Perminder S. Sachdev, Vincent P. Clark, Ian H. Gotlib, Susanne Erk, Henrik Walter, Dennis van den Meer, Simon Cervenka, Oliver Grimm, Andrew M. McIntosh, Alexander Tomyshev, Francisco X. Castellanos, Bernd Kramer, Klaus-Peter Lesch, Odile A. van den Heuvel, Sophia I. Thomopoulos, Diana Tordesillas-Gutiérrez, Terry L. Jernigan, Yulyia Yoncheva, Anouk den Braber, Jim Lagopoulos, Maria J. Portella, Ole A. Andreassen, Gaelle E. Doucet, Avram J. Holmes, Nynke A. Groenewold, Pedro G.P. Rosa, Hilleke E. Hulshoff Pol, Sanne Koops, José M. Menchón, Jan K. Buitelaar, Dan J. Stein, Dorret I. Boomsma, Lei Wang, C.A. Hartman, Pascual Sánchez-Juan, Andreas Heinz, European Commission, National Institute of Child Health and Human Development (US), QIMR Berghofer Medical Research Institute (Australia), University of Queensland, National Cancer Institute (US), Dutch Research Council, Netherlands Organisation for Health Research and Development, National Institute of Mental Health (US), European Research Council, National Center for Advancing Translational Sciences (US), Medical Research Council (UK), Fundación Marques de Valdecilla, Instituto de Salud Carlos III, Swedish Research Council, South-Eastern Norway Regional Health Authority, Research Council of Norway, Icahn School of Medicine at Mount Sinai, South London and Maudsley NHS Foundation Trust, NHS Foundation Trust, National Institute for Health Research (UK), Clinical Cognitive Neuropsychiatry Research Program (CCNP), Movement Disorder (MD), Developmental Neuroscience in Society, Child and Adolescent Psychiatry / Psychology, Adult Psychiatry, APH - Mental Health, ANS - Complex Trait Genetics, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, Child Psychiatry, ANS - Cellular & Molecular Mechanisms, General Paediatrics, ARD - Amsterdam Reproduction and Development, Karolinska Schizophrenia Project (KaSP), Ontwikkelingspsychologie (Psychologie, FMG), Psychiatry, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Epidemiology and Data Science, Neurology, Amsterdam Neuroscience - Neurodegeneration, Pediatric surgery, Anatomy and neurosciences, Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention, Amsterdam Neuroscience - Brain Imaging, RS: MHeNs - R2 - Mental Health, Psychiatrie & Neuropsychologie, Biological Psychology, APH - Methodology, Complex Trait Genetics, Amsterdam Neuroscience - Complex Trait Genetics, Educational and Family Studies, Cognitive Psychology, IBBA, Clinical Neuropsychology, Faculty of Behavioural and Movement Sciences, and APH - Personalized Medicine

Subjects
Male, Aging, Neurologi, Audiology, Trajectories, 0302 clinical medicine, 130 000 Cognitive Neurology & Memory, diagnostic imaging [Cerebral Cortex], Child, Research Articles, Cerebral Cortex, Psychiatry, Aged, 80 and over, Radiological and Ultrasound Technology, Fractional polynomial, 05 social sciences, Radiology, Nuclear Medicine & Medical Imaging, 1. No poverty, Cognition, Middle Aged, Cerebral cortex, Regression, 3. Good health, Escorça cerebral, Neurology, Radiology Nuclear Medicine and imaging, Healthy individuals, Child, Preschool, anatomy & histology [Cerebral Cortex], Female, Analysis of variance, Anatomy, Life Sciences & Biomedicine, Trajectorie, Research Article, Neuroinformatics, Adult, medicine.medical_specialty, Adolescent, Human Development, Clinical Neurology, BF, Neuroimaging, Biology, Development, 050105 experimental psychology, Psykiatri, Cortical thickness, 03 medical and health sciences, Young Adult, Neuroimaging genetics, Envelliment, medicine, Humans, trajectories, 0501 psychology and cognitive sciences, Radiology, Nuclear Medicine and imaging, ddc:610, development, Aged, Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7], Science & Technology, Brain morphometry, aging, Neurosciences, cortical thickness, Cross-Sectional Studies, RC0321, Neurology (clinical), Neurosciences & Neurology, 030217 neurology & neurosurgery, physiology [Human Development]
Abstract

Special Issue: The ENIGMA Consortium: the first 10 years., Delineating the association of age and cortical thickness in healthy individuals is critical given the association of cortical thickness with cognition and behavior. Previous research has shown that robust estimates of the association between age and brain morphometry require large-scale studies. In response, we used cross-sectional data from 17,075 individuals aged 3–90 years from the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to infer age-related changes in cortical thickness. We used fractional polynomial (FP) regression to quantify the association between age and cortical thickness, and we computed normalized growth centiles using the parametric Lambda, Mu, and Sigma method. Interindividual variability was estimated using meta-analysis and one-way analysis of variance. For most regions, their highest cortical thickness value was observed in childhood. Age and cortical thickness showed a negative association; the slope was steeper up to the third decade of life and more gradual thereafter; notable exceptions to this general pattern were entorhinal, temporopolar, and anterior cingulate cortices. Interindividual variability was largest in temporal and frontal regions across the lifespan. Age and its FP combinations explained up to 59% variance in cortical thickness. These results may form the basis of further investigation on normative deviation in cortical thickness and its significance for behavioral and cognitive outcomes., European Community's Seventh Framework Programme, Grant/Award Numbers: 278948, 602450, 603016, 602805; US National Institute of Child Health and Human Development, Grant/Award Numbers: RO1HD050735, 1009064, 496682; QIMR Berghofer Medical Research Institute and the Centre for Advanced Imaging, University of Queensland; ICTSI NIH/NCRR, Grant/Award Number: RR025761; European Community's Horizon 2020 Programme, Grant/Award Numbers: 667302, 643051; Vici Innovation Program, Grant/Award Numbers: #91619115, 016-130-669; NWO Brain & Cognition Excellence Program, Grant/Award Number: 433-09-229; Biobanking and Biomolecular Resources Research Infrastructure (Netherlands) (BBMRI-NL); Spinozapremie, Grant/Award Number: NWO-56-464-14192; Biobanking and Biomolecular Resources Research Infrastructure, Grant/Award Numbers: 184.033.111, 184.021.007; Netherlands Organization for Health Research and Development (ZonMW), Grant/Award Numbers: 480-15-001/674, 024.001.003, 911-09-032, 056-32-010, 481-08-011, 016-115-035, 31160008, 400-07-080, 400-05-717, 451-04-034, 463-06-001, 480-04-004, 904-61-193, 912-10-020, 985-10-002, 904-61-090; NIMH, Grant/Award Number: R01 MH090553; Geestkracht programme of the Dutch Health Research Council, Grant/Award Number: 10-000-1001; FP7 Ideas: European Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Grant/Award Numbers: NWO/SPI 56-464-14192, NWO-MagW 480-04-004, 433-09-220, NWO 51.02.062, NWO 51.02.061; National Center for Advancing Translational Sciences, National Institutes of Health, Grant/Award Number: UL1 TR000153; National Center for Research Resources; National Center for Research Resources at the National Institutes of Health, Grant/Award Numbers: NIH 1U24 RR025736-01, NIH 1U24 RR021992; NIH Institutes contributing to the Big Data to Knowledge; U.S. National Institutes of Health, Grant/Award Numbers: R01 CA101318, P30 AG10133, R01 AG19771; Medical Research Council, Grant/Award Numbers: U54EB020403, G0500092; National Institute of Mental Health, Grant/Award Numbers: R01MH117014, R01MH042191; Fundación Instituto de Investigación Marqués de Valdecilla, Grant/Award Numbers: API07/011, NCT02534363, NCT0235832; Instituto de Salud Carlos III, Grant/Award Numbers: PI14/00918, PI14/00639, PI060507, PI050427, PI020499; Swedish Research Council, Grant/Award Numbers: 523-2014-3467, 2017-00949, 521-2014-3487; South-Eastern Norway Health Authority; the Research Council of Norway, Grant/Award Number: 223273; South Eastern Norway Regional Health Authority, Grant/Award Numbers: 2017-112, 2019107; Icahn School of Medicine at Mount Sinai; Seventh Framework Programme (FP7/2007-2013), Grant/Award Number: 602450; National Institutes of Health, Grant/Award Numbers: R01 MH116147, R01 MH113619, R01 MH104284; South London and Maudsley NHS Foundation Trust; the National Institute for Health Research (NIHR)

Published
2022

3. Professionals' motivation to support parental self‐management regarding children with physical disability in Dutch rehabilitation services: ‘Please mind your gap’

Author

Carlo Schuengel, Ruud Wong Chung, J.M. Voorman, Agnes Willemen, Jules G. Becher, Marjolijn Ketelaar, VU University medical center, Clinical Child and Family Studies, LEARN! - Child rearing, APH - Mental Health, APH - Quality of Care, APH - Aging & Later Life, and Educational and Family Studies

Subjects
Parents, paediatric rehabilitation, professionals' beliefs, Physical disability, media_common.quotation_subject, medicine.medical_treatment, partnership, education, Qualitative property, Coaching, Developmental psychology, 03 medical and health sciences, 0302 clinical medicine, Professional-Family Relations, 030225 pediatrics, Perception, Health care, Developmental and Educational Psychology, medicine, Humans, Family, 0501 psychology and cognitive sciences, Child, Research Articles, coaching skills, Qualitative Research, health care economics and organizations, media_common, Motivation, Rehabilitation, Self-management, parental self‐management support, business.industry, Self-Management, 05 social sciences, Public Health, Environmental and Occupational Health, humanities, Content analysis, Pediatrics, Perinatology and Child Health, business, Psychology, Research Article, 050104 developmental & child psychology
Abstract

BACKGROUND: Professionals in child healthcare increasingly endorse the support of self-management in paediatric rehabilitation services for children with physical disability. Less understood though are their views regarding the role of the children's parents, as well as their own role in supporting parents. This study aimed to investigate the motivation of rehabilitation professionals to support self-management of parents regarding their child with physical disability, professionals' beliefs about parental self-management, and the perceptions underlying their motivation.METHODS: A mixed-methods strategy was followed using a survey among rehabilitation professionals (n = 175) and consecutive semi-structured interviews (n = 16). Associations between autonomous (intrinsic) versus controlled (extrinsic) motivation and beliefs on parental self-management were tested. For deeper understanding of their motivation, directed content analysis was used to address key themes in the qualitative data extracts.RESULTS: Professionals reported autonomous motivation for parental self-management support more often than controlled motivation (t(174) = 29.95, p < .001). Autonomous motivation was associated with the beliefs about the importance of parental self-management (r = .29, p < .001). Approximately 90% of the professionals believed that parents should have an active role, though less than ten percent considered it important that parents also are independent actors and initiative takers in the rehabilitation process. Interviews revealed that individual professionals struggled with striking a balance between keeping control and "giving away responsibility" to parents. A "professional-like" attitude was expected of parents with "involvement" and "commitment" as essential preconditions. Furthermore, professionals expressed the need for additional coaching skills to support parental self-management.CONCLUSION: Professionals were predominantly autonomously motivated to support self-management of parents. However, the dilemmas in giving or taking responsibilities within the partnership with parents, may limit their effectiveness in empowering parents. Reflection on the potential gaps between professionals' motivation, beliefs, and actual behaviour might be crucial to support parental self-management.

Published
2021

4. Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years

Author

Tiffany M. Chaim-Avancini, Suzanne C. Swagerman, Sophie Maingault, Mauricio H. Serpa, Kang Sim, Patricia Gruner, Dara M. Cannon, Esther Walton, Gunter Schumann, Christopher R.K. Ching, Simon E. Fisher, Tomohiro Nakao, Nhat Trung Doan, Sophia I. Thomopoulos, Diana Tordesillas-Gutiérrez, Ilya M. Veer, Lieuwe de Haan, Paul Pauli, Derrek P. Hibar, Kun Yang, Dan J. Stein, Dominik Grotegerd, Víctor Ortiz-García de la Foz, Daniel Brandeis, Sarah Baumeister, Xavier Caseras, Fabrice Crivello, Vincent P. Clark, Maria J. Portella, Salvador Sarró, Dorret I. Boomsma, Henry Völzke, Daniel H. Wolf, Lianne Schmaal, Yannis Paloyelis, Barbara Franke, Matthew D. Sacchet, Anne Uhlmann, Yulyia Yoncheva, Ole A. Andreassen, Erick J. Canales-Rodríguez, Ingrid Agartz, Anouk den Braber, Colm McDonald, Edith Pomarol-Clotet, Anders M. Dale, Calhoun Vd, David Mataix-Cols, Ignacio Martínez-Zalacaín, Joshua L. Roffman, Andrew J. Kalnin, Anton Albajes-Eizagirre, Andreas Reif, Won Hee Lee, Gaelle E. Doucet, Hans-Jörgen Grabe, Pieter J. Hoekstra, Avram J. Holmes, Theophilus N. Akudjedu, Ian H. Gotlib, Fleur M. Howells, Andrew J. Saykin, Genevieve McPhilemy, Moji Aghajani, David C. Glahn, Rachel M. Brouwer, Núria Bargalló, Knut Schnell, Katharina Wittfeld, Thomas Frodl, Josiane Bourque, Ryota Kanai, Raymond Salvador, Sean N. Hatton, Terry L. Jernigan, Helena Fatouros-Bergman, Oliver Grimm, Marise W. J. Machielsen, Victoria Chubar, Henk Temmingh, Andrew M. McIntosh, Georg C. Ziegler, Marieke Klein, T. P. Klyushnik, Iris E. C. Sommer, Heather C. Whalley, Rachel E. Gur, Alan Breier, Jordan W. Smoller, Kathryn I. Alpert, Dick J. Veltman, Neda Jahanshad, Sophia Frangou, Jiyang Jiang, Jessica A. Turner, Eveline A. Crone, Thomas Espeseth, Alexander Tomyshev, Christine Lochner, Anthony A. James, Aristotle N. Voineskos, Julian N. Trollor, Efstathios Papachristou, Beng-Choon Ho, Pablo Najt, Christian K. Tamnes, Geraldo F. Busatto, Stefan Borgwardt, Andreas Meyer-Lindenberg, Philip Asherson, Francisco X. Castellanos, Bernd Kramer, Jim Lagopoulos, Marcus V. Zanetti, Joaquim Radua, John A. Joska, Giulio Pergola, Nynke A. Groenewold, Erlend S. Dørum, Henrik Walter, Jan Egil Nordvik, Alessandro Bertolino, Wei Wen, Klaus-Peter Lesch, Ian B. Hickie, Pedro G.P. Rosa, Randy L. Buckner, Daniel A. Rinker, Hilleke E. Hulshoff Pol, Steven G. Potkin, Odile A. van den Heuvel, Nancy C. Andreasen, Sanne Koops, Amanda Worker, Susanne Erk, Lei Wang, Norbert Hosten, Jean-Paul Fouche, Dennis van 't Ent, Jonna Kuntsi, Dennis van den Meer, Simon Cervenka, C.A. Hartman, Nicholas G. Martin, Carles Soriano-Mas, Neeltje E.M. van Haren, Pascual Sánchez-Juan, Andreas Heinz, Brenna C. McDonald, Thomas H. Wassink, José M. Menchón, Katie L. McMahon, Jan K. Buitelaar, Sarah E. Medland, Aurora Bonvino, Patricia J. Conrod, Nic J.A. van der Wee, Paul M. Thompson, Micael Andersson, Perminder S. Sachdev, Lars Nyberg, Eco J. C. de Geus, Ramona Baur-Streubel, Lachlan T. Strike, Dag Alnæs, Paola Fuentes-Claramonte, Ben J. Harrison, Martine Hoogman, Lars T. Westlye, Annette Conzelmann, Annabella Di Giorgio, Benedicto Crespo-Facorro, Sarah Hohmann, Jilly Naaijen, Yang Wang, Henry Brodaty, Greig I. de Zubicaray, Laura Koenders, Ruben C. Gur, Stefan Ehrlich, Danai Dima, Christopher G. Davey, Tobias Banaschewski, Amirhossein Modabbernia, Dirk J. Heslenfeld, Erik G. Jönsson, Oliver Gruber, Theodore D. Satterthwaite, René S. Kahn, Margaret J. Wright, Jaap Oosterlaan, Steven Williams, Bernard Mazoyer, Lara M. Wierenga, Bernd Weber, Luisa Lázaro, Irina Lebedeva, Erin W. Dickie, Chaim Huyser, John D. West, Theo G.M. van Erp, National Institute of Mental Health (US), Karolinska Institute, Stockholm County Council, South-Eastern Norway Regional Health Authority, German Centre for Cardiovascular Research, Siemens Healthcare, University of Queensland, Eunice Kennedy Shriver National Institute of Child Health and Human Development (US), National Health and Medical Research Council (Australia), National Institute on Drug Abuse (US), Indiana State Department of Health, Parents of children with epilepsy, Epilepsy Therapy Project, Fight Against Childhood Epilepsy and Seizures, Epilepsy Foundation, American Epilepsy Society, Knut and Alice Wallenberg Foundation, European Commission, Dutch Research Council, Netherlands Organization for Scientific Research, Netherlands Brain Foundation, Utrecht University, European Research Council, National Center for Advancing Translational Sciences (US), National Institutes of Health (US), National Center for Research Resources (US), Fundación Marques de Valdecilla, Instituto de Salud Carlos III, Swedish Research Council, Kings College London, South London and Maudsley NHS Foundation Trust, NIHR Biomedical Research Centre (UK), National Institute for Health Research (UK), RS: MHeNs - R2 - Mental Health, Psychiatrie & Neuropsychologie, Karolinska Schizophrenia Project (KaSP), Biological Psychology, APH - Mental Health, APH - Methodology, Complex Trait Genetics, Amsterdam Neuroscience - Complex Trait Genetics, Educational and Family Studies, Cognitive Psychology, IBBA, Clinical Neuropsychology, Faculty of Behavioural and Movement Sciences, APH - Personalized Medicine, Developmental Neuroscience in Society, Child and Adolescent Psychiatry / Psychology, Adult Psychiatry, ANS - Complex Trait Genetics, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, Child Psychiatry, ANS - Cellular & Molecular Mechanisms, General Paediatrics, ARD - Amsterdam Reproduction and Development, Clinical Cognitive Neuropsychiatry Research Program (CCNP), Movement Disorder (MD), Psychiatry, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Neurology, Amsterdam Neuroscience - Neurodegeneration, Pediatric surgery, Anatomy and neurosciences, Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention, and Amsterdam Neuroscience - Brain Imaging

Subjects
Male, diagnostic imaging [Corpus Striatum], Physiology, Hippocampus, Edat, Morfologia (Biologia), Lateral ventricles, anatomy & histology [Corpus Striatum], 0302 clinical medicine, Thalamus, 130 000 Cognitive Neurology & Memory, Basal ganglia, diagnostic imaging [Amygdala], Child, Cervell, Research Articles, diagnostic imaging [Hippocampus], Aged, 80 and over, Radiological and Ultrasound Technology, Putamen, Radiology, Nuclear Medicine & Medical Imaging, 05 social sciences, ENIGMA, Multisi, Brain, Middle Aged, Amygdala, 3. Good health, Neurology, Child, Preschool, Brain size, Female, Anatomy, Life Sciences & Biomedicine, Neurovetenskaper, Research Article, Neuroinformatics, Adult, Adolescent, anatomy & histology [Hippocampus], Human Development, multisite, BF, Neuroimaging, Nucleus accumbens, Biology, Brain morphometry, Morphology (Biology), 050105 experimental psychology, Young Adult, 03 medical and health sciences, Age, Longitudinal trajectories, brain morphometry, Humans, 0501 psychology and cognitive sciences, Radiology, Nuclear Medicine and imaging, ddc:610, anatomy & histology [Thalamus], Aged, diagnostic imaging [Thalamus], Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7], Science & Technology, Neurosciences, Corpus Striatum, nervous system, anatomy & histology [Amygdala], RC0321, Neurosciences & Neurology, longitudinal trajectories, Neurology (clinical), 030217 neurology & neurosurgery, physiology [Human Development]
Abstract

Special Issue: The ENIGMA Consortium: the first 10 years.-- Karolinska Schizophrenia Project (KaSP)., Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted age coverage and significant methodological variability. These limitations introduce inconsistencies and may obscure or distort the lifespan trajectories of brain morphometry. In response, we capitalized on the resources of the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to examine age-related trajectories inferred from cross-sectional measures of the ventricles, the basal ganglia (caudate, putamen, pallidum, and nucleus accumbens), the thalamus, hippocampus and amygdala using magnetic resonance imaging data obtained from 18,605 individuals aged 3–90 years. All subcortical structure volumes were at their maximum value early in life. The volume of the basal ganglia showed a monotonic negative association with age thereafter; there was no significant association between age and the volumes of the thalamus, amygdala and the hippocampus (with some degree of decline in thalamus) until the sixth decade of life after which they also showed a steep negative association with age. The lateral ventricles showed continuous enlargement throughout the lifespan. Age was positively associated with inter-individual variability in the hippocampus and amygdala and the lateral ventricles. These results were robust to potential confounders and could be used to examine the functional significance of deviations from typical age-related morphometric patterns., National Institute of Mental Health, Grant/Award Numbers: MH104284, MH116147, R01MH113619, R01 MH090553, R01MH117014, R01MH042191; Karolinska Institutet; Stockholm County Council; Southern and Eastern Norway Regional Health Authority; German Centre for Cardiovascular Research; DZHK; Siemens Healthineers; University of Queensland; US National Institute of Child Health and Human Development, Grant/Award Number: RO1HD050735; Australian National Health and Medical Research Council; Eunice Kennedy Shriver National Institute of Child Health & Human Development; National Institute on Drug Abuse, Grant/Award Numbers: UL1 TR000153, 1 U24 RR025736-01, 1 U24 RR021992; Brain Injury Fund Research Grant Program; Indiana State Department of Health Spinal Cord; Parents Against Childhood Epilepsy; Epilepsy Therapy Project, Fight Against Childhood Epilepsy and Seizures; Epilepsy Foundation; American Epilepsy Society; Knut and Alice Wallenberg Foundation; European Community's Horizon 2020 Programme; Vici Innovation Program; NWO Brain & Cognition Excellence Program; Netherlands Organization for Scientific Research; Hersenstichting Nederland; Netherlands Organization for Health Research and Development; Geestkracht Programme of the Dutch Health Research Council, Grant/Award Number: 10-000-1001; Universiteit Utrecht; FP7 Ideas: European Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Center for Advancing Translational Sciences; National Institutes of Health; National Center for Research Resources; Consortium grant, Grant/Award Number: U54 EB020403; U.S. National Institutes of Health, Grant/Award Numbers: R01 CA101318, P30 AG10133, R01 AG19771; Medical Research Council, Grant/Award Number: G0500092; Fundación Instituto de Investigación Marqués de Valdecilla, Grant/Award Numbers: API07/011, NCT02534363, NCT0235832; Instituto de Salud Carlos III, Grant/Award Numbers: PI14/00918, PI14/00639, PI060507, PI050427, PI020499; the Research Council, Grant/Award Number: 223273; South Eastern Norway Regional Health Authority, Grant/Award Numbers: 2017-112, 2019107; Swedish Research Council; European Community's Seventh Framework Programme, Grant/Award Number: 602450; King's College London; South London and Maudsley NHS Foundation Trust; Biomedical Research Centre; National Institute for Health Research.

Published
2021

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