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15 results on '"Cosme Silva"'

1. Antifungal Activity, Antibiofilm and Association Studies with O ‐Alkylamidoximes against Cryptococcus spp

Author

Anna Paula de Castro Teixeira, Gustavo Fernandes Queiroga Moraes, Romário Jonas de Oliveira, Cosme Silva Santos, Rodrigo Ribeiro Alves Caiana, Juliano Carlo Rufino de Freitas, Ulrich Vasconcelos, Fillipe de Oliveira Pereira, and Igara Oliveira Lima

Subjects
Molecular Medicine, Bioengineering, General Chemistry, General Medicine, Molecular Biology, Biochemistry
Published
2023
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2. Effect of red wine or its polyphenols on induced apical periodontitis in rats

Author

Renan Dal-Fabbro, Luciano Tavares Angelo Cintra, Flávia Alfredo Plazza, Fernanda Rezende Silva Martins de Oliveira, Leopoldo Cosme-Silva, Edilson Ervolino, Letícia Cabrera Capalbo, João Eduardo Gomes-Filho, Universidade Estadual Paulista (UNESP), University of Michigan, and Federal University of Alagoas (UFAL)

Subjects
Molar, medicine.medical_specialty, Wine, Inflammation, resveratrol, Resveratrol, Bone resorption, quercetin, chemistry.chemical_compound, Internal medicine, medicine, Animals, Rats, Wistar, wine, General Dentistry, polyphenols, Periodontitis, Periapical periodontitis, business.industry, Polyphenols, X-Ray Microtomography, medicine.disease, periapical periodontitis, Rats, Resorption, Endocrinology, chemistry, medicine.symptom, business, Quercetin, Periapical Periodontitis
Abstract

Made available in DSpace on 2022-05-01T09:31:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Aim: To evaluate the effect of red wine consumption or its polyphenols on the inflammation/resorption processes associated with apical periodontitis in rats. Methodology: Thirty-two three-month-old Wistar rats had apical periodontitis induced in four first molars and were then arranged into four groups: control (C)—rats with apical periodontitis; wine (W)—rats with apical periodontitis receiving 4.28 ml/kg of red wine; resveratrol+quercetin (R+Q)—rats with apical periodontitis receiving 4.28 ml/kg of a solution containing 1.00 mg/L of quercetin and 0.86 mg/L of resveratrol and alcohol (ALC)—rats with apical periodontitis receiving the alcoholic dose contained in the wine. The oral gavage treatments were administered daily, from day 0 to day 45. On the 15th day, apical periodontitis was induced, and on the 45th day, the animals were euthanized. Histological, immunohistochemical (RANKL, OPG, TRAP, IL-10, TNF-⍺ and IL-1β) and micro-computed tomography for bone resorption analysis were performed in the jaws. The Kruskal–Wallis with Dunn's test was performed for nonparametric data, and the anova with Tukey's test for parametric data, p

Published
2021
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3. Design, Synthesis and Antitumoral Activity of New O ‐Alkylamidoximes

Author

Juliano Carlo Rufino Freitas, Antônio A. Soares-Paulino, Renato Ferreira de Almeida Júnior, Kleber Juvenal Silva Farias, Paulo H. Menezes, Rodrigo Ribeiro Alves Caiana, Paula Renata Lima Machado, Cosme Silva Santos, and Romário Jonas de Oliveira

Subjects
Design synthesis, Chemistry, General Chemistry, Alkylation, Combinatorial chemistry
Published
2021
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7. Design, Synthesis and Antitumoral Activity of New O ‐Alkylamidoximes

Author

Oliveira, Romário Jonas, primary, Santos, Cosme Silva, additional, Caiana, Rodrigo Ribeiro Alves, additional, Farias, Kleber Juvenal Silva, additional, Almeida Júnior, Renato Ferreira, additional, Machado, Paula Renata Lima, additional, Soares‐Paulino, Antônio Augusto, additional, Menezes, Paulo Henrique, additional, and Freitas, Juliano Carlo Rufino, additional

Published
2021
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