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113 results on '"Cook, G"'

1. P23 EMAGINE/CARTITUDE-6: A RANDOMIZED PHASE 3 STUDY OF DVRD FOLLOWED BY CILTACABTAGENE AUTOLEUCEL VERSUS DVRD FOLLOWED BY AUTOLOGOUS STEM CELL TRANSPLANT IN TRANSPLANT-ELIGIBLE PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA

Author

Broijl, A., primary, San-Miguel, J., additional, Suzuki, K., additional, Krishnan, A., additional, van de Donk, N., additional, Cook, G., additional, Jakubowiak, A., additional, Madduri, D., additional, Afifi, S., additional, Stevens, A., additional, Schecter, J., additional, Deraedt, W., additional, Kuppens, S., additional, Mistry, P., additional, Pacaud, L., additional, Boccadoro, M., additional, Gay, F., additional, Mina, R., additional, Rasche, L., additional, Moreau, P., additional, Mateos, M., additional, Einsele, H., additional, and Sonneveld, P., additional

Published
2023
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2. 'No one's ever said anything about sleep': A qualitative investigation into mothers' experiences of sleep in children with epilepsy

Author

Cook, G, Gringras, P, Hiscock, H, Pal, DK, Wiggs, L, Cook, G, Gringras, P, Hiscock, H, Pal, DK, and Wiggs, L

Abstract

INTRODUCTION: Sleep problems in children with epilepsy (CWE) are common. However, little is known about parental experiences and feelings about managing sleep in their CWE. To provide the most appropriate services' provision, it is essential that the lived experience of parents of this patient group and the issues and problems that they face in managing their child's sleep is understood. METHOD: In 2018, nine mothers of CWE (aged 5-15 years) were interviewed about their perceptions and experiences around their child's sleep, sleep problems and their management, the impact of sleep difficulties on the child and their family and available support. RESULTS: Four themes were identified that represented the nature of the child's sleep problems, including settling and night-waking issues, parasomnias and child anxiety around sleep. Seven themes represented mothers' experiences of managing their child's sleep and any associated problems, including the longstanding challenging nature of child sleep issues, management strategies adopted, challenges related to managing sleep over time, the link between sleep and seizures, the negative impact of poor sleep on daytime functioning, role of antiseizure medication and maternal concerns about child sleep. One theme represented the perceived lack of information, help and support available. CONCLUSIONS: Findings suggest there are unmet needs in supporting parents to deal with sleep, sleep problems and their management in CWE. PATIENT OR PUBLIC CONTRIBUTION: This individual study was conducted under the umbrella of the CASTLE research programme (see https://castlestudy.org.uk/). Parents who have lived experience of parenting a child with epilepsy were co-applicants for the programme and were involved in the original conception, aims, design and funding application for the research programme (including the project reported in this paper) and advised on project design. Mothers of CWE who have lived experience of managing sleep and sleep

Published
2023

3. Evolution or revolution in multiple myeloma therapy and the role of the UK

Author

Cook, G and Morris, CTCM

Abstract

The knowledge of disease biology as well as the therapeutic landscape in multiple myeloma (MM) has expanded exponentially in recent years. These advances have seen improvements in survivorship, not only in the clinical trial setting but also in the real setting. Importantly there is also every evidence to indicate that such improvements in our understanding and treatments will continue. This article is not intended to be a comprehensive review; rather it aims to give a temporal context to these developments with exemplars, and highlight the central role that UK clinicians, healthcare workers, scientists and most importantly patients and their relatives have played in this revolution.

Published
2020

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