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2 results on '"Christian Ciardi"'

1. Author response for 'Covid‐19 fatality prediction in people with diabetes and prediabetes using a simple score at hospital admission'

Author

Mario Karolyi, Tm. Stulnig, O. Malle, Reinhard Würfel, M. Wagner, Caren Sourij, Lars Stechemesser, Brigitte Bernhardt, Erich Pawelka, Susanne Kaser, Michael Resl, E. Pawelka, Peter Wolf, Christian Ciardi, Martin Clodi, F. Aziz, Michael Wagner, C. Ress, A. Kautzky‐Willer, Gersina Rega‐Kaun, Roland Feldbauer, A. Oulhaj, Michael Schranz, Thomas M. Stulnig, C Ciardi, Anna Schapfl, A. Bräuer, L. Stechemesser, P. Wolf, Kadriye Aydinkov‐Tuzcu, A. Zitterl, Marc Schaber, S. Kaser, Johannes Pohlhammer, M. Clodi, Harald Stingl, M. Karolyi, Norbert J. Tripolt, Alexandra Kautzky-Willer, C. Klammer, Carmen Klammer, Claudia Ress, N. Tripolt, Slobodan Peric, Farah Abbas, H. Stingl, C. Sourij, Andreas Zitterl, Harald Sourij, Matthias Heinzl, H. Sourij, Alexander Bräuer, P. Fasching, Oliver Malle, S. Peric, Julia K. Mader, David Fiegl, and Peter Fasching

Subjects
medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), business.industry, Simple (abstract algebra), Diabetes mellitus, Hospital admission, Emergency medicine, medicine, Prediabetes, medicine.disease, business
Published
2020

2. Effects of Pronounced Weight Loss on Adiponectin Oligomer Composition and Metabolic Parameters*

Author

Markus Laimer, Christoph Ebenbichler, Herbert Tilg, Tobias Tatarczyk, Joachim Spranger, Clemens Molnar, Thomas Bobbert, Helmut Weiss, Josef R. Patsch, Julia Engl, Christian Ciardi, and Susanne Kaser

Subjects
Blood Glucose, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Gastric Bypass, Medicine (miscellaneous), Oligomer, Body Mass Index, Anthropometric parameters, chemistry.chemical_compound, Endocrinology, Western blot, Weight loss, Internal medicine, Weight Loss, medicine, Humans, Protein Isoforms, Obesity, Surgical treatment, Hmw adiponectin, Nutrition and Dietetics, Adiponectin, medicine.diagnostic_test, Lipids, Obesity, Morbid, Adipose Tissue, chemistry, Body Composition, Female, Composition (visual arts), medicine.symptom, Biomarkers
Abstract

Objective: Adiponectin is an adipocytokine secreted into circulation in three isoforms. The aim of the study was to investigate changes of adiponectin isoforms during profound weight loss and its relation to anthropomorphometric and metabolic parameters. Research Methods and Procedures: Thirteen severely obese female subjects were examined before and 1 year after surgical treatment. Total adiponectin was determined by radioimmunosorbent assay, and oligomer composition was detected by nondenaturing Western blot. Results: BMI decreased substantially (p < 0.001), which was associated with an increase of total adiponectin from 12.9 ± 5.9 to 14.3 ± 6.1 μg/mL (p = 0.055). Medium molecular weight (MMW) adiponectin increased from 7.5 ± 3.6 to 9.1 ± 4.1 μg/mL (p = 0.009), whereas high (HMW) and low molecular weight adiponectin remained unchanged. Δ values of total adiponectin correlated significantly with Δ values of anthropometric parameters. Similar correlations were found for Δ values of MMW (Δ weight: r2 = 0.4132, p = 0.0178; Δ BMI: r2 = 0.3319, p = 0.0393; Δ fat mass: r2 = 0.5202, p = 0.0054). Discussion: Thus, profound weight loss was associated with an increase in total adiponectin, which was mainly and consistently caused by increases in MMW adiponectin (p = 0.009). These changes result in a shift from low molecular weight to MMW and HMW adiponectin isoforms, which may be related to improvements in both anthropometric and metabolic parameters.

Published
2007

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