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2. Diagnosis, management and prevention ofCandida aurisin hospitals: position statement of the Australasian Society for Infectious Diseases

Author

Rita Roy, Chong W. Ong, Catriona Halliday, Christopher H. Heath, Andrew J. Stewardson, Julia E Clark, Leon J Worth, Monica A. Slavin, Caroline Marshall, Deborah Marriott, Arthur J. Morris, Sarah E. Kidd, C. Orla Morrissey, and Sharon C.-A. Chen

Subjects
medicine.medical_specialty, Antifungal Agents, Antifungal drug, Microbial Sensitivity Tests, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Drug Resistance, Fungal, Amphotericin B, Amphotericin B deoxycholate, Disease Transmission, Infectious, Internal Medicine, Humans, Medicine, Infection control, 030212 general & internal medicine, DNA, Fungal, Intensive care medicine, Fluconazole, Societies, Medical, Candida, Cross Infection, Infection Control, business.industry, Age Factors, Australia, Candidiasis, Outbreak, Candida auris, Diagnosis management, business, New Zealand, medicine.drug
Abstract

Candida auris is an emerging drug-resistant yeast responsible for hospital outbreaks. This statement reviews the evidence regarding diagnosis, treatment and prevention of this organism and provides consensus recommendations for clinicians and microbiologists in Australia and New Zealand. C. auris has been isolated in over 30 countries (including Australia). Bloodstream infections are the most frequently reported infections. Infections have crude mortality of 30-60%. Acquisition is generally healthcare-associated and risks include underlying chronic disease, immunocompromise and presence of indwelling medical devices. C. auris may be misidentified by conventional phenotypic methods. Matrix-assisted laser desorption ionisation time-of-flight mass spectrometry or sequencing of the internal transcribed spacer regions and/or the D1/D2 regions of the 28S ribosomal DNA are therefore required for definitive laboratory identification. Antifungal drug resistance, particularly to fluconazole, is common, with variable resistance to amphotericin B and echinocandins. Echinocandins are currently recommended as first-line therapy for infection in adults and children ≥2 months of age. For neonates and infants

Published
2019

5. Expanding the phenotype in argininosuccinic aciduria: need for new therapies

Author

Baruteau, Julien, primary, Jameson, Elisabeth, additional, Morris, Andrew A., additional, Chakrapani, Anupam, additional, Santra, Saikat, additional, Vijay, Suresh, additional, Kocadag, Huriye, additional, Beesley, Clare E., additional, Grunewald, Stephanie, additional, Murphy, Elaine, additional, Cleary, Maureen, additional, Mundy, Helen, additional, Abulhoul, Lara, additional, Broomfield, Alexander, additional, Lachmann, Robin, additional, Rahman, Yusof, additional, Robinson, Peter H., additional, MacPherson, Lesley, additional, Foster, Katharine, additional, Chong, W. Kling, additional, Ridout, Deborah A., additional, Bounford, Kirsten McKay, additional, Waddington, Simon N., additional, Mills, Philippa B., additional, Gissen, Paul, additional, and Davison, James E., additional

Published
2017
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16. Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression

Author

Soo, Julia K., primary, MacKenzie Ross, Alastair D., additional, Kallenberg, David M., additional, Milagre, Carla, additional, Heung Chong, W., additional, Chow, Jade, additional, Hill, Lucy, additional, Hoare, Stacey, additional, Collinson, Rebecca S., additional, Hossain, Mehnaz, additional, Keith, W. Nicol, additional, Marais, Richard, additional, and Bennett, Dorothy C., additional

Published
2011
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19. ChemInform Abstract: Structure-Activity Relationships of the Antimalarial Agent Artemisinin. Part 2. Effect of Heteroatom Substitution at O-11: Synthesis and Bioassay of N-Alkyl-11-aza-9-desmethylartemisinins.

Author

AVERY, M. A., primary, BONK, J. D., additional, CHONG, W. K. M., additional, MEHROTRA, S., additional, MILLER, R., additional, MILHOUS, W., additional, GOINS, D. K., additional, VENKATESAN, S., additional, WYANDT, C., additional, KHAN, I., additional, and AVERY, B. A., additional

Published
2010
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28. Sickle cell disease: Ischemia and seizures

Author

Prengler, Mara, primary, Pavlakis, Steven G., additional, Boyd, Stewart, additional, Connelly, Alan, additional, Calamante, Fernando, additional, Chong, W. K., additional, Saunders, Dawn, additional, Cox, Timothy, additional, Bynevelt, Michael, additional, Lane, Roderick, additional, Laverty, Aidan, additional, and Kirkham, Fenella J., additional

Published
2005
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29. Sickle cell disease and electroencephalogram hyperventilation

Author

Prengler, Mara, primary, Pavlakis, Steven G., additional, Boyd, Stewart, additional, Connelly, Alan, additional, Calamante, Fernando, additional, Chong, W. K., additional, Saunders, Dawn, additional, Cox, Timothy, additional, Bynevelt, Michael, additional, Lane, Roderick, additional, Laverty, Aidan, additional, and Kirkham, Fenella J., additional

Published
2005
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31. Poststreptococcal acute disseminated encephalomyelitis with basal ganglia involvement and auto‐reactive antibasal ganglia antibodies

Author

Dale, Russell C., primary, Church, Andrew J., additional, Cardoso, Francisco, additional, Goddard, Elizabeth, additional, Cox, Tim C., additional, Chong, W. K. “Kling”, additional, Williams, Amanda, additional, Klein, Nigel J., additional, Neville, Brian G., additional, Thompson, Edward J., additional, and Giovannoni, Gavin, additional

Published
2001
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38. Comparison of Modified Urea Fertilizers and Estimation of Their Availability Coefficient Using Quadratic Models

Author

Hernan R. Tejeda, Chong W. Hong, and Paul L. G. Vlek

Subjects
Response model, Chemistry, Soil Science, Limiting, engineering.material, chemistry.chemical_compound, Quadratic equation, Agronomy, Yield (chemistry), Statistics, engineering, Urea, Fertilizer, Quadratic response, Complete response
Abstract

A procedure to compare N fertilizers based on comparing complete response curves simultaneously represented by a quadratic multifertilizer response model (MRM) is discussed. A modified version of the MRM, called fertilizer testing model (FTM), is used to test differences among response curves. The FTM describes the response curve to a fertilizer selected as a standard as well as the additional effect of test fertilizers over the response to the standard. In case of different response curves, an approximate test to decide whether the curves have equal limiting yield is introduced. Finally, a procedure to estimate the availability coefficient from quadratic response curves having equal limiting yield is derived. These procedures were employed to analyze six field experiments conducted over a period of 3 years in Korea using three varieties of rice (Oryza sativa L. ‘Tongil,’ ‘Jinheung,’ and ‘Milyang 23’) and three fertilizers (urea and two sulfur-coated ureas, or SCU) applied at four or five levels of N. Two out of six experiments showed a significant effect from SCU-A (25% release/7 days) beyond that of split-applied urea, whereas SCU-B (14% release/7 days) showed significant additional effects in three out of five experiments. However, in four of these six experiments, the limiting yield of the response curves of SCU was significantly higher than that of urea, precluding a valid estimation of the availability coefficient. Possibly, the proper combination of N dose and timed release of N from SCU in these experiments translated into grain yields unmatched by split applications of urea.

Published
1980

39. Polymer studies by gel permeation chromatography

Author

Chong W. Kim, William B. Smith, and James A. May

Subjects
Gel permeation chromatography, chemistry.chemical_classification, Chemical kinetics, chemistry.chemical_compound, Chromatography, chemistry, Bulk polymerization, Size-exclusion chromatography, Analytical chemistry, Thermoresponsive polymers in chromatography, Polymer, Polystyrene, Methyl methacrylate
Abstract

Samples of polystyrene and poly(methyl methacrylate) have been prepared by bulk polymerization under conditions previously investigated in the literature. The molecular weight distributions were determined for early-conversion samples by gel permeation chromatography, and the experimental distribution curves were compared with calculated curves based on kinetic data. The agreement between the experimental and calculated curves was such as to indicate the utility of gel permeation chromatography in the investigation of polymer reaction kinetics and mechanisms.

Published
1966

40. Effect of Fluoride on Ribosomes from Corn Roots. Changes with Growth Retardation

Author

Chong W. Chang

Subjects
Differential centrifugation, Physiology, RNA, Cell Biology, Plant Science, General Medicine, Ribosomal RNA, Ribosome, chemistry.chemical_compound, Column chromatography, chemistry, Biochemistry, Ribosomal protein, Genetics, Growth inhibition, Fluoride
Abstract

Growth inhibition caused by fluoride was further studied by analyzing free and bound ribosomes, and the ribosomal components in corn roots. Ribosomes were isolated by differential centrifugation. Ribosomal components were analyzed by column chromatography and electrophoresis. Fluoride reduces the amounts of both free and bound ribosomes. Fluoride also modifies the RNA to protein ratio of bound ribosomes more than that of free ribosomes. Fluoride does not affect base ratios of the ribosomal RNA, but reduces its content and changes the structure of the ribosomal protein moiety.

Published
1970

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