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27 results on '"Chen, Yu‐Chi"'

10. An Arbitrary Color Light Emitter

Author

Tan, Wei‐Chun, primary, Chen, Yu‐Chi, additional, Liou, Yi‐Rou, additional, Hu, Han‐Wen, additional, Hofmann, Mario, additional, and Chen, Yang‐Fang, additional

Published
2016
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13. Micromachined membrane filters for microwave and millimeter-wave applications (invited article)

Author

Chen-Yu Chi, Thomas M. Weller, S.V. Robertson, Gabriel M. Rebeiz, and Linda P. B. Katehi

Subjects
Waveguide filter, Engineering, business.industry, General Engineering, Microstrip, Resonator, Surface micromachining, Band-pass filter, Electronic engineering, Insertion loss, Optoelectronics, business, Active filter, Stripline
Abstract

Recent developments in micromachining techniques at the University of Michigan have resulted in novel high-performance low-loss filters for microwave and millimeter-wave applications. The idea is based on suspending the filters on thin dielectric membranes to eliminate dielectric loss and dispersion problems, resulting in a pure TEM mode of propagation and conductor-loss-limited performance. The dielectric membrane and the surrounding cavities are built using chemical etching in Silicon and GaAs wafers. The filters are therefore compatible with low-cost IC fabrication techniques and can be com- bined with planar diodes and transistors to result in active filter networks. Several state-of-the-art filters have been realized including 15-GHz and 20-GHz bandpass interdigi- tal suspended stripline filters, lowpass and bandpass microshield filters at 30 GHz and 90 GHz, microstrip 94-GHz bandpass filters, and a 250-GHz bandpass filter with 1.0-1.5-dB insertion loss. This article reviews the associated fabrication techniques, the different types of transmission lines achieved using this technology, and the measured performance from 15 to 350 GHz. The study concludes with a detailed description of the future work in this area. Q 1997 John Wiley & Sons, Inc. Int J Microwa'e Millimeter-Wa'e CAE 7: 149-166, 1997.

Published
1997

23. Transcription of proteinase 3 and related myelopoiesis genes in peripheral blood mononuclear cells of patients with active Wegener's granulomatosis

Author

Cheadle, Chris, primary, Berger, Alan E., additional, Andrade, Felipe, additional, James, Regina, additional, Johnson, Kristen, additional, Watkins, Tonya, additional, Park, Jin Kyun, additional, Chen, Yu-Chi, additional, Ehrlich, Eva, additional, Mullins, Marissa, additional, Chrest, Francis, additional, Barnes, Kathleen C., additional, and Levine, Stuart M., additional

Published
2010
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26. Trajectories of symptom severity predicts quality of life change in newly diagnosis lymphoma survivors: An initial study.

Author

Wu CJ, Chen YC, Bai LY, Chiou TJ, Lin KC, and Wang YJ

Subjects
Male, Humans, Middle Aged, Prospective Studies, Survivors, Fatigue etiology, Quality of Life, Lymphoma
Abstract

Objective: This study aimed to explore the subgroups of symptom severity and impact of their trajectories on quality of life in lymphoma survivors., Methods: Secondary data were analysed from a prospective study with four-time measures: before treatment (T1), during treatment (T2), treatment completion (T3) and 10 weeks after treatment (T4). Data were analysed using descriptive statistics, group-based trajectory model and generalised estimation equation., Results: Fifty nine of 61 participants completed three-time measure (mean age = 60.43 years, male-predominant). The changes in symptom severity over time were divided into two subgroups: slight-stable group (n = 54, 89%) and mild-fickle group (n = 7, 11%). Pain, tiredness and sleeping trouble were the predominant symptoms. The quality of life change in the slight-stable group was significantly better than that of the mild-fickle group (B = 13.35, SE = 3.53, p < 0.001). The overall quality of life at T2, T3 and T4 was better than it was at T1., Conclusion: The different trajectories of symptom severity significantly influenced quality of life changes in lymphoma survivors. Healthcare providers must be aware that there is a group of lymphoma survivors with relatively severe symptoms when newly diagnosed, compared to the opposite. More attention must be paid to this group, in addition to providing in-time symptom management., (© 2022 John Wiley & Sons Ltd.)

Published
2022
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27. MiRNA mimic screen for improved expression of functional neurotensin receptor from HEK293 cells.

Author

Xiao S, Chen YC, Betenbaugh MJ, Martin SE, and Shiloach J

Subjects
Humans, Luciferases analysis, Luciferases genetics, Mass Screening, MicroRNAs genetics, Receptors, Neurotensin genetics, Gene Expression, HEK293 Cells physiology, MicroRNAs metabolism, Receptors, Neurotensin biosynthesis
Abstract

Obtaining adequate quantities of functional mammalian membrane proteins has been a bottleneck in their structural and functional studies because the expression of these proteins from mammalian cells is relatively low. To explore the possibility of enhancing expression of these proteins using miRNA, a stable T-REx-293 cell line expressing the neurotensin receptor type 1 (NTSR1), a hard-to-express G protein-coupled receptor (GPCR), was constructed. The cell line was then subjected to human miRNA mimic library screening. In parallel, an HEK293 cell line expressing luciferase was also screened with the same human miRNA mimic library. Five microRNA mimics: hsa-miR-22-5p, hsa-miR-18a-5p, hsa-miR-22-3p, hsa-miR-429, and hsa-miR-2110were identified from both screens. They led to 48% increase in the expression of functional NTSR1 and to 239% increase of luciferase expression. These miRNAs were also effective in enhancing the expression of secretedglypican-3 hFc-fusion protein from HEK293 cells.The results indicate that these molecules may have a wide role in enhancing the production of proteins with biomedical interest., (© 2015 Wiley Periodicals, Inc.)

Published
2015
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