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18 results on '"Chen, Heidi"'

2. Reply

Author

Aboudara, Matthew, primary, Roller, Lance, additional, Rickman, Otis, additional, Lentz, Robert J., additional, Pannu, Jasleen, additional, Chen, Heidi, additional, and Maldonado, Fabien, additional

Published
2020
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3. New‐onset posttransplant diabetes mellitus after haploidentical hematopoietic cell transplantation with posttransplant cyclophosphamide

Author

Mangan, Brendan L., primary, Patel, Dilan, additional, Chen, Heidi, additional, Gatwood, Katie S., additional, Byrne, Michael T., additional, Sengsayadeth, Salyka, additional, Goodman, Stacey, additional, Dholaria, Bhagirathbhai, additional, Kassim, Adetola A., additional, Jagasia, Madan, additional, Chinratanalab, Wichai, additional, Culos, Kathryn A., additional, and Engelhardt, Brian G., additional

Published
2020
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4. Early viral reactivation despite excellent immune reconstitution following haploidentical Bone marrow transplant with post‐transplant cytoxan for sickle cell disease

Author

Patel, Dilan A., primary, Dhedin, Nathalie, additional, Chen, Heidi, additional, Karnik, Leena, additional, Gatwood, Katie, additional, Culos, Katie, additional, Mohan, Sanjay, additional, Engelhardt, Brian G., additional, Kitko, Carrie, additional, Connelly, Jim, additional, Satyanarayana, Gowri, additional, Jagasia, Madan, additional, De La Fuente, Josu, additional, and Kassim, Adetola, additional

Published
2019
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9. Targeting SLC1a5-mediated glutamine dependence in non-small cell lung cancer

Author

Hassanein, Mohamed, primary, Qian, Jun, additional, Hoeksema, Megan D., additional, Wang, Jing, additional, Jacobovitz, Marie, additional, Ji, Xiangming, additional, Harris, Fredrick T., additional, Harris, Bradford K., additional, Boyd, Kelli L., additional, Chen, Heidi, additional, Eisenberg, Rosana, additional, and Massion, Pierre P., additional

Published
2015
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14. Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma

Author

Shinohara, Eric T., primary, Gonzalez, Adriana, additional, Massion, Pierre P., additional, Chen, Heidi, additional, Li, Ming, additional, Freyer, Andrea S., additional, Olson, Sandra J., additional, Andersen, Jeremiah J., additional, Shyr, Yu, additional, Carbone, David P., additional, Johnson, David H., additional, Hallahan, Dennis E., additional, and Lu, Bo, additional

Published
2005
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17. Pediatric Otolaryngology Short-Term Mission Outcomes at a Surgical Mission Hospital in Guatemala.

Author

Richard K, Sanchez R, Amado B, Lubner R, Niconchuk J, Chen H, Phillips J, Kynes M, and Belcher RH

Subjects
Child, Humans, Guatemala, Retrospective Studies, Cleft Palate surgery, Cleft Lip surgery, Medical Missions, Otolaryngology
Abstract

Objective: The frequency of humanitarian surgical mission trips has grown over recent decades. Unfortunately, research on patient outcomes from these trips has not increased proportionately. We aim to analyze the safety and efficacy of surgeries in a low- and middle-income country missions-based surgery center in Guatemala City, Guatemala, and identify factors that influence surgical outcomes., Study Design: Retrospective cohort study., Setting: Guatemalan surgery center is called the Moore Center., Methods: Pediatric patients underwent otolaryngology surgery between 2017 and 2019. All patients required follow up. We analyzed the effect of patient, surgical, and geographic factors on follow up and complications with univariate and multivariate analyses., Results:  A total of 1094 otolaryngologic surgeries were performed between 2017 to 2019, which comprised 37.4% adenotonsillectomies, 26.8% cleft lip (CL)/cleft palate (CP) repairs, 13.6% otologic, and 20% "other" surgeries. Patients traveled on average 88 km to the center (±164 km). Eighty-nine percent attended their first follow up and 55% attended their second. The 11% who missed their first follow up lived farther from the center (p < .001) and had a higher ASA classification (p < .001) than the 89% who did attend. Sixty-nine (6.3%) patients had 1 or more complications. CL/CP surgery was associated with more complications than other procedures (p < .001). Of 416 tonsillectomies, 4 patients (1%) had a bleeding episode with 2 requiring reoperation., Conclusion: This surgical center models effective surgical care in low-resource areas. Complications and follow-up length vary by diagnosis. Areas to improve include retaining complex patients for follow up and reducing complications for CL/CP repair., (© 2023 American Academy of Otolaryngology-Head and Neck Surgery Foundation.)

Published
2024
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18. Expression of focal adhesion kinase in small-cell lung carcinoma.

Author

Ocak S, Chen H, Callison C, Gonzalez AL, and Massion PP

Subjects
Aged, Female, Focal Adhesion Kinase 1 genetics, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms diagnosis, Lung Neoplasms genetics, Lung Neoplasms mortality, Male, Middle Aged, Neoplasm Staging, Paxillin metabolism, Phosphorylation, Small Cell Lung Carcinoma diagnosis, Small Cell Lung Carcinoma genetics, Small Cell Lung Carcinoma mortality, Survival Analysis, Focal Adhesion Kinase 1 metabolism, Lung Neoplasms metabolism, Small Cell Lung Carcinoma metabolism
Abstract

Background: The focal adhesion kinase (FAK) is a non-receptor tyrosine kinase linked to tumor growth, invasion, and metastasis. FAK is overexpressed and associated with prognosis in many cancers, but its prognostic value in small-cell lung carcinoma (SCLC) is unknown and was the focus of this study., Methods: Total FAK expression was analyzed via immunohistochemistry in tissue microarrays consisting of formalin-fixed, paraffin-embedded SCLC specimens from 85 patients. FAK staining scores were tested for correlations with pathological characteristics and clinical outcomes. Phospho-paxillin was also tested in 35 of the 85 specimens to evaluate whether FAK expression was associated with downstream signaling., Results: Specific FAK expression was localized to the cytoplasm of 78/85 (92%) SCLCs. FAK expression was scored low in 11 (13%), moderate in 17 (20%), and high in 50 (59%) SCLCs. FAK staining scores treated as continuous variables did not correlate with SCLC disease stage, response to therapy, recurrence/progression-free survival, or overall survival. Moreover, total FAK expression did not correlate with phospho-paxillin Tyr(118) expression., Conclusions: Total FAK is strongly expressed in a majority of SCLC tumors. However, the expression evaluated via immunohistochemistry is not a prognostic factor in patients with SCLC., (Copyright © 2011 American Cancer Society.)

Published
2012
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