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2. Outcomes after definitive radiation therapy for localized prostate cancer in a national health care delivery system

Author

Herr, DJ, Elliott, DA, Duchesne, G, Stensland, KD, Caram, MEV, Chapman, C, Burns, JA, Hollenbeck, BK, Sparks, JB, Shin, C, Zaslavsky, A, Tsodikov, A, Skolarus, TA, Herr, DJ, Elliott, DA, Duchesne, G, Stensland, KD, Caram, MEV, Chapman, C, Burns, JA, Hollenbeck, BK, Sparks, JB, Shin, C, Zaslavsky, A, Tsodikov, A, and Skolarus, TA

Abstract

PURPOSE: Accurate information regarding real-world outcomes after contemporary radiation therapy for localized prostate cancer is important for shared decision-making. Clinically relevant end points at 10 years among men treated within a national health care delivery system were examined. METHODS: National administrative, cancer registry, and electronic health record data were used for patients undergoing definitive radiation therapy with or without concurrent androgen deprivation therapy within the Veterans Health Administration from 2005 to 2015. National Death Index data were used through 2019 for overall and prostate cancer-specific survival and identified date of incident metastatic prostate cancer using a validated natural language processing algorithm. Metastasis-free, prostate cancer-specific, and overall survival using Kaplan-Meier methods were estimated. RESULTS: Among 41,735 men treated with definitive radiation therapy, the median age at diagnosis was 65 years and median follow-up was 8.7 years. Most had intermediate (42%) and high-risk (33%) disease, with 40% receiving androgen deprivation therapy as part of initial therapy. Unadjusted 10-year metastasis-free survival was 96%, 92%, and 80% for low-, intermediate-, and high-risk disease. Similarly, unadjusted 10-year prostate cancer-specific survival was 98%, 97%, and 90% for low-, intermediate-, and high-risk disease. The unadjusted overall survival was lower across increasing disease risk categories at 77%, 71%, and 62% for low-, intermediate-, and high-risk disease (p < .001). CONCLUSIONS: These data provide population-based 10-year benchmarks for clinically relevant end points, including metastasis-free survival, among patients with localized prostate cancer undergoing radiation therapy using contemporary techniques. The survival rates for high-risk disease in particular suggest that outcomes have recently improved.

Published
2023

3. Lifestyle risks for chronic disease among Australian adolescents: a cross-sectional survey.

Author

Champion, KE, Chapman, C, Gardner, LA, Sunderland, M, Newton, NC, Smout, S, Thornton, LK, Hides, L, McBride, N, Allsop, SJ, Mills, K, Kay-Lambkin, F, Teesson, M, Slade, T, Heath4Life team, Champion, KE, Chapman, C, Gardner, LA, Sunderland, M, Newton, NC, Smout, S, Thornton, LK, Hides, L, McBride, N, Allsop, SJ, Mills, K, Kay-Lambkin, F, Teesson, M, Slade, T, and Heath4Life team

Published
2022

6. A service evaluation of FIT and anaemia for risk stratification in the two week wait pathway for colorectal cancer

Author

Chapman, C., Bunce, J., Oliver, S., Ng, O., Tangri, A., Rogers, R., Logan, R.F., Humes, D.J., and Banerjea, A.

Subjects
digestive system diseases
Abstract

Introduction: New national guidance on urgent referral for investigation for Colorectal Cancer (CRC) included faecal occult blood testing in 2015. We evaluated faecal immunochemical testing (FIT) and anaemia as risk stratification tools in symptomatic patients suspected of having CRC.Methods: Postal FIT was incorporated into the CRC two week wait (2WW) pathway for all patients without rectal bleeding in 2016. Patients were investigated in the 2WW pathway as normal and outcomes of investigations were prospectively recorded. Anaemia was defined as haemoglobin less than 120g/L in women and less than 130g/L in men.Results: FIT kits were sent to 1106 patients with an 80.9% return rate; 810 patients completed investigation with 40 CRCs diagnosed (4.9%). Median FIT results were significantly higher in patients who were anaemic (median 4.8 iqr 0.8-34.1 versus 1.2 iqr 0-6.4, Mann-Whitney p less than 0.001).Some 538 (60.4%) had a result of less than 4 µgHb/gFaeces (limit of detectability) and 621 (69.7%) a result less than 10 µgHb/gFaeces. Sixty per cent of CRCs had a FIT reading of >150 µgHb/gFaeces. Five CRCs diagnosed in patients with a FIT4 µgHb/gFaeces had 97.5% sensitivity and 64.5% specificity for CRC diagnosis. A FIT result of >4 µgHb/gFaeces and/or anaemia had a 100% sensitivity and 45.3% specificity for CRC diagnosis.Conclusion: FIT is most useful at the extremes of detectability; strongly positive readings predict high rates of CRC and other significant pathology, whilst very low readings in the absence of anaemia or palpable rectal mass identify a group with very low risk. High return rates for FIT within this 2WW pathway indicate its acceptability.

Published
2019

7. Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations

Author

Bancroft, EK, Saya, S, Page, EC, Myhill, K, Thomas, S, Pope, J, Chamberlain, A, Hart, R, Glover, W, Cook, J, Rosario, DJ, Helfand, BT, Selkirk, CH, Davidson, R, Longmuir, M, Eccles, DM, Gadea, N, Brewer, C, Barwell, J, Salinas, M, Greenhalgh, L, Tischkowitz, M, Henderson, A, Evans, DG, Buys, SS, Eeles, RA, Aaronson, NK, Eeles, R, Bancroft, E, Page, E, Kote-Jarai, Z, Ardern-Jones, A, Bangma, C, Castro, E, Dearnaley, D, Falconer, A, Foster, C, Gronberg, H, Hamdy, FC, Johannsson, OT, Khoo, V, Eccles, D, Lilja, H, Evans, G, Eyfjord, J, Lubinski, J, Maehle, L, Mikropoulos, C, Millner, A, Mitra, A, Offman, J, Moynihan, C, Rennert, G, Suri, M, Dias, A, Taylor, N, D'Mello, L, James, P, Mitchell, G, Shanley, S, Richardson, K, McKinley, J, Petelin, L, Murphy, M, Mascarenhas, L, Murphy, D, Lam, J, Taylor, L, Miller, C, Stapleton, A, Chong, M, Suthers, G, Poplawski, N, Tucker, K, Andrews, L, Duffy, J, Millard, R, Ward, R, Williams, R, Stricker, P, Kirk, J, Bowman, M, Patel, M, Harris, M, O'Connell, S, Hunt, C, Smyth, C, Frydenberg, M, Lindeman, G, Shackleton, K, Morton, C, Susman, R, McGaughran, J, Boon, M, Pachter, N, Townshend, S, Schofield, L, Nicholls, C, Spigelman, A, Gleeson, M, Amor, D, Burke, J, Patterson, B, Swindle, P, Scott, R, Foulkes, W, Boshari, T, Aprikian, A, Jensen, T, Bojeson, A, Osther, P, Skytte, A-B, Cruger, D, Tondering, MK, Gerdes, A-M, Schmutzler, R, Rhiem, K, Wihler, P, Kast, K, Griebsch, C, Johannsson, O, Stefansdottir, V, Murthy, V, Sarin, R, Awatagiri, K, Ghonge, S, Kowtal, P, Mulgund, G, Gallagher, D, Bambury, R, Farrell, M, Gallagher, F, Kiernan, I, Friedman, E, Chen-Shtoyerman, R, Basevitch, A, Leibovici, D, Melzer, E, Ben-Yehoshua, SJ, Nicolai, N, Radice, P, Valdagni, R, Magnani, T, Gay, S, Teo, SH, Tan, HM, Yoon, S-Y, Thong, MK, Vasen, H, Ringleberg, J, van Asperen, C, Kiemeney, B, van Zelst-Stams, W, Ausems, MGEM, van der Luijt, RB, van Os, T, Ruijs, MWG, Adank, MA, Oldenburg, RA, Helderman-van den Enden, APTJM, Caanen, BAH, Oosterwijk, JC, Moller, P, Brennhovd, B, Medvik, H, Hanslien, E, Grindedal, EM, Cybulski, C, Wokolorczyk, D, Teixeira, M, Maia, S, Peixoto, A, Henrique, R, Oliveira, J, Goncalves, N, Araujo, L, Seixas, M, Souto, JP, Nogueira, P, Copakova, L, Zgajnar, J, Krajc, M, Vrecar, A, Capella, G, Ramon y Cajal, T, Fisas, D, Mora, J, Esquena, S, Balmana, J, Morote, J, Liljegren, A, Hjalm-Eriksson, M, Ekdahl, K-J, Carlsson, S, George, A, Kemp, Z, Wiggins, J, Moss, C, Van As, N, Thompson, A, Ogden, C, Woodhouse, C, Kumar, P, Bulman, B, Rothwell, J, Tricker, K, Wise, G, Mercer, C, McBride, D, Costello, P, Pearce, A, Torokwa, A, Paterson, J, Clowes, V, Taylor, A, Newcombe, B, Walker, L, Halliday, D, Stayner, B, Fleming-Brown, D, Snape, K, Hanson, H, Hodgson, S, Brice, G, Homfray, T, Hammond, C, Kohut, K, Anjum, U, Dearing, A, Mencias, M, Potter, A, Renton, C, Searle, A, Hill, K, Goodman, S, Garcia, L, Devlin, G, Everest, S, Nadolski, M, Douglas, F, Jobson, I, Paez, E, Donaldson, A, Tomkins, S, Langman, C, Jacobs, C, Pichert, G, Shaw, A, Kulkarni, A, Tripathi, V, Rose, S, Compton, C, Watson, M, Reinholtz, C, Brady, A, Dorkins, H, Melville, A, Kosicka-Slawinska, M, Cummings, C, Kiesel, V, Bartlett, M, Randhawa, K, Ellery, N, Side, L, Male, A, Simon, K, Rees, K, Tidey, L, Gurasashvili, J, Nevitt, L, Ingram, S, Howell, A, Rosario, D, Catto, J, Howson, J, Ong, K-R, Chapman, C, Cole, T, Heaton, T, Hoffman, J, Burgess, L, Huber, C, Islam, F, Watt, C, Duncan, A, Kockelbergh, R, Mzazi, S, Dineen, A, Sattar, A, Kaemba, B, Sidat, Z, Patel, N, Siguake, K, Birt, A, Poultney, U, Umez-Eronini, N, Mom, J, Sutton, V, Cornford, P, Bermingham, N, Yesildag, P, Treherne, K, Griffiths, J, Cogley, L, Gott, H, Rubinstein, WS, Hulick, P, McGuire, M, Shevrin, D, Kaul, K, Weissman, S, Newlin, A, Vogel, K, Weiss, S, Hook, N, Buys, S, Goldgar, D, Conner, T, Venne, V, Stephenson, R, Dechet, C, Domchek, S, Powers, J, Rustgi, N, Strom, S, Arun, B, Davis, JW, Yamamura, Y, Obeid, E, Giri, V, Gross, L, Bealin, L, Cooney, K, Stoffel, E, Okoth, L, Bancroft, EK, Saya, S, Page, EC, Myhill, K, Thomas, S, Pope, J, Chamberlain, A, Hart, R, Glover, W, Cook, J, Rosario, DJ, Helfand, BT, Selkirk, CH, Davidson, R, Longmuir, M, Eccles, DM, Gadea, N, Brewer, C, Barwell, J, Salinas, M, Greenhalgh, L, Tischkowitz, M, Henderson, A, Evans, DG, Buys, SS, Eeles, RA, Aaronson, NK, Eeles, R, Bancroft, E, Page, E, Kote-Jarai, Z, Ardern-Jones, A, Bangma, C, Castro, E, Dearnaley, D, Falconer, A, Foster, C, Gronberg, H, Hamdy, FC, Johannsson, OT, Khoo, V, Eccles, D, Lilja, H, Evans, G, Eyfjord, J, Lubinski, J, Maehle, L, Mikropoulos, C, Millner, A, Mitra, A, Offman, J, Moynihan, C, Rennert, G, Suri, M, Dias, A, Taylor, N, D'Mello, L, James, P, Mitchell, G, Shanley, S, Richardson, K, McKinley, J, Petelin, L, Murphy, M, Mascarenhas, L, Murphy, D, Lam, J, Taylor, L, Miller, C, Stapleton, A, Chong, M, Suthers, G, Poplawski, N, Tucker, K, Andrews, L, Duffy, J, Millard, R, Ward, R, Williams, R, Stricker, P, Kirk, J, Bowman, M, Patel, M, Harris, M, O'Connell, S, Hunt, C, Smyth, C, Frydenberg, M, Lindeman, G, Shackleton, K, Morton, C, Susman, R, McGaughran, J, Boon, M, Pachter, N, Townshend, S, Schofield, L, Nicholls, C, Spigelman, A, Gleeson, M, Amor, D, Burke, J, Patterson, B, Swindle, P, Scott, R, Foulkes, W, Boshari, T, Aprikian, A, Jensen, T, Bojeson, A, Osther, P, Skytte, A-B, Cruger, D, Tondering, MK, Gerdes, A-M, Schmutzler, R, Rhiem, K, Wihler, P, Kast, K, Griebsch, C, Johannsson, O, Stefansdottir, V, Murthy, V, Sarin, R, Awatagiri, K, Ghonge, S, Kowtal, P, Mulgund, G, Gallagher, D, Bambury, R, Farrell, M, Gallagher, F, Kiernan, I, Friedman, E, Chen-Shtoyerman, R, Basevitch, A, Leibovici, D, Melzer, E, Ben-Yehoshua, SJ, Nicolai, N, Radice, P, Valdagni, R, Magnani, T, Gay, S, Teo, SH, Tan, HM, Yoon, S-Y, Thong, MK, Vasen, H, Ringleberg, J, van Asperen, C, Kiemeney, B, van Zelst-Stams, W, Ausems, MGEM, van der Luijt, RB, van Os, T, Ruijs, MWG, Adank, MA, Oldenburg, RA, Helderman-van den Enden, APTJM, Caanen, BAH, Oosterwijk, JC, Moller, P, Brennhovd, B, Medvik, H, Hanslien, E, Grindedal, EM, Cybulski, C, Wokolorczyk, D, Teixeira, M, Maia, S, Peixoto, A, Henrique, R, Oliveira, J, Goncalves, N, Araujo, L, Seixas, M, Souto, JP, Nogueira, P, Copakova, L, Zgajnar, J, Krajc, M, Vrecar, A, Capella, G, Ramon y Cajal, T, Fisas, D, Mora, J, Esquena, S, Balmana, J, Morote, J, Liljegren, A, Hjalm-Eriksson, M, Ekdahl, K-J, Carlsson, S, George, A, Kemp, Z, Wiggins, J, Moss, C, Van As, N, Thompson, A, Ogden, C, Woodhouse, C, Kumar, P, Bulman, B, Rothwell, J, Tricker, K, Wise, G, Mercer, C, McBride, D, Costello, P, Pearce, A, Torokwa, A, Paterson, J, Clowes, V, Taylor, A, Newcombe, B, Walker, L, Halliday, D, Stayner, B, Fleming-Brown, D, Snape, K, Hanson, H, Hodgson, S, Brice, G, Homfray, T, Hammond, C, Kohut, K, Anjum, U, Dearing, A, Mencias, M, Potter, A, Renton, C, Searle, A, Hill, K, Goodman, S, Garcia, L, Devlin, G, Everest, S, Nadolski, M, Douglas, F, Jobson, I, Paez, E, Donaldson, A, Tomkins, S, Langman, C, Jacobs, C, Pichert, G, Shaw, A, Kulkarni, A, Tripathi, V, Rose, S, Compton, C, Watson, M, Reinholtz, C, Brady, A, Dorkins, H, Melville, A, Kosicka-Slawinska, M, Cummings, C, Kiesel, V, Bartlett, M, Randhawa, K, Ellery, N, Side, L, Male, A, Simon, K, Rees, K, Tidey, L, Gurasashvili, J, Nevitt, L, Ingram, S, Howell, A, Rosario, D, Catto, J, Howson, J, Ong, K-R, Chapman, C, Cole, T, Heaton, T, Hoffman, J, Burgess, L, Huber, C, Islam, F, Watt, C, Duncan, A, Kockelbergh, R, Mzazi, S, Dineen, A, Sattar, A, Kaemba, B, Sidat, Z, Patel, N, Siguake, K, Birt, A, Poultney, U, Umez-Eronini, N, Mom, J, Sutton, V, Cornford, P, Bermingham, N, Yesildag, P, Treherne, K, Griffiths, J, Cogley, L, Gott, H, Rubinstein, WS, Hulick, P, McGuire, M, Shevrin, D, Kaul, K, Weissman, S, Newlin, A, Vogel, K, Weiss, S, Hook, N, Buys, S, Goldgar, D, Conner, T, Venne, V, Stephenson, R, Dechet, C, Domchek, S, Powers, J, Rustgi, N, Strom, S, Arun, B, Davis, JW, Yamamura, Y, Obeid, E, Giri, V, Gross, L, Bealin, L, Cooney, K, Stoffel, E, and Okoth, L

Abstract

OBJECTIVES: To report the baseline results of a longitudinal psychosocial study that forms part of the IMPACT study, a multi-national investigation of targeted prostate cancer (PCa) screening among men with a known pathogenic germline mutation in the BRCA1 or BRCA2 genes. PARTICPANTS AND METHODS: Men enrolled in the IMPACT study were invited to complete a questionnaire at collaborating sites prior to each annual screening visit. The questionnaire included sociodemographic characteristics and the following measures: the Hospital Anxiety and Depression Scale (HADS), Impact of Event Scale (IES), 36-item short-form health survey (SF-36), Memorial Anxiety Scale for Prostate Cancer, Cancer Worry Scale-Revised, risk perception and knowledge. The results of the baseline questionnaire are presented. RESULTS: A total of 432 men completed questionnaires: 98 and 160 had mutations in BRCA1 and BRCA2 genes, respectively, and 174 were controls (familial mutation negative). Participants' perception of PCa risk was influenced by genetic status. Knowledge levels were high and unrelated to genetic status. Mean scores for the HADS and SF-36 were within reported general population norms and mean IES scores were within normal range. IES mean intrusion and avoidance scores were significantly higher in BRCA1/BRCA2 carriers than in controls and were higher in men with increased PCa risk perception. At the multivariate level, risk perception contributed more significantly to variance in IES scores than genetic status. CONCLUSION: This is the first study to report the psychosocial profile of men with BRCA1/BRCA2 mutations undergoing PCa screening. No clinically concerning levels of general or cancer-specific distress or poor quality of life were detected in the cohort as a whole. A small subset of participants reported higher levels of distress, suggesting the need for healthcare professionals offering PCa screening to identify these risk factors and offer additional information and support t

Published
2019

8. Randomised trial of population‐based BRCA testing in Ashkenazi Jews: long‐term outcomes

Author

Manchanda, R, primary, Burnell, M, additional, Gaba, F, additional, Desai, R, additional, Wardle, J, additional, Gessler, S, additional, Side, L, additional, Sanderson, S, additional, Loggenberg, K, additional, Brady, AF, additional, Dorkins, H, additional, Wallis, Y, additional, Chapman, C, additional, Jacobs, C, additional, Legood, R, additional, Beller, U, additional, Tomlinson, I, additional, Menon, U, additional, and Jacobs, I, additional

Published
2019
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10. Attitude towards and factors affecting uptake of population‐basedBRCAtesting in the Ashkenazi Jewish population: a cohort study

Author

Manchanda, R, primary, Burnell, M, additional, Gaba, F, additional, Sanderson, S, additional, Loggenberg, K, additional, Gessler, S, additional, Wardle, J, additional, Side, L, additional, Desai, R, additional, Brady, AF, additional, Dorkins, H, additional, Wallis, Y, additional, Chapman, C, additional, Jacobs, C, additional, Tomlinson, I, additional, Beller, U, additional, Menon, U, additional, and Jacobs, I, additional

Published
2019
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14. An HLA-B null allele (B*0808N) caused by a nucleotide deletion in exon 3, found in the family of a bone marrow transplant recipient

Author

Gary Cavanagh, S. Day, Chapman C, P.P.J. Dunn, J. Ross, and Carter

Subjects
Genetics, Immunology, General Medicine, Human leukocyte antigen, Biology, Biochemistry, Molecular biology, Null allele, HLA-B, Frameshift mutation, law.invention, Exon, law, Immunology and Allergy, Typing, Allele, Polymerase chain reaction
Abstract

We have identified a variant HLA-B allele, B*0808N, segregating through two generations of healthy individuals, whilst HLA typing the family of a bone marrow patient. Serological typing identified a disparity between the father (A1, A3 B7 DR7) and the brother (A1, A2 B56 DR1, DR7) of the patient. Low/medium resolution polymerase chain reaction using sequence-specific primers (PCR-SSP) revealed a B*08 allele undetectable by serological methods. High resolution DNA typing by polymerase chain reaction-sequencing based typing (PCR-SBT), revealed a nucleotide deletion at position 131 (C) in exon 3, the only difference between the new allele and B*0801. The deletion results in a frame shift in the protein coding sequence, introducing a premature termination codon (TGA) in exon 4. Although a B*08 allele is present in these individuals, the deletion prevents correct expression of the antigen on the cell surface ( Note).

Published
2000

19. The prevalence, influential factors and mechanisms of relative age effects in UK Rugby League

Author

Till, K, Cobley, S, Wattie, N, O'Hara, J, Cooke, CB, and Chapman, C

Subjects
education, human activities
Abstract

Relative age effects (RAEs), reflecting observed inequalities in participation and attainment as a result of annual age-grouping policies in youth sport, are common in most team sports. The aims of this study were to determine if and when RAEs become apparent in Rugby League, determine how influential variables (e.g., gender) lead and clarify whether player retention at junior representative levels can explain persistent RAEs. Player data were collected for the male and female community games ranging from Under 7s to Senior (N=15,060) levels, junior representative selections (i.e., Regional) and professional players (N=298). Chi-square analyses found significant (P

Published
2010

24. Early-life hygiene-related factors affect risk of central nervous system demyelination and asthma differentially

Author

Hughes, A.-M., primary, Lucas, R. M., additional, McMichael, A. J., additional, Dwyer, T., additional, Pender, M. P., additional, van der Mei, I., additional, Taylor, B. V., additional, Valery, P., additional, Chapman, C., additional, Coulthard, A., additional, Dear, K., additional, Kilpatrick, T. J., additional, Williams, D., additional, and Ponsonby, A.-L., additional

Published
2013
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29. Receptor protein tyrosine phosphatase sigma regulates synapse structure, function and plasticity

Author

Horn, Katherine E., primary, Xu, Bin, additional, Gobert, Delphine, additional, Hamam, Bassam N., additional, Thompson, Katherine M., additional, Wu, Chia-Lun, additional, Bouchard, Jean-François, additional, Uetani, Noriko, additional, Racine, Ronald J., additional, Tremblay, Michel L., additional, Ruthazer, Edward S., additional, Chapman, C. Andrew, additional, and Kennedy, Timothy E., additional

Published
2012
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30. Funding nature conservation: who pays?

Author

Evans, D. M., primary, Barnard, P., additional, Koh, L. P., additional, Chapman, C. A., additional, Altwegg, R., additional, Garner, T. W. J., additional, Gompper, M. E., additional, Gordon, I. J., additional, Katzner, T. E., additional, and Pettorelli, N., additional

Published
2012
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31. Measures to prevent transfusion-related acute lung injury (TRALI)

Author

Reesink, H. W., primary, Lee, J., additional, Keller, A., additional, Dennington, P., additional, Pink, J., additional, Holdsworth, R., additional, Schennach, H., additional, Goldman, M., additional, Petraszko, T., additional, Sun, J., additional, Meng, Y., additional, Qian, K., additional, Rehacek, V., additional, Turek, P., additional, Krusius, T., additional, Juvonen, E., additional, Tiberghien, P., additional, Legrand, D., additional, Semana, G., additional, Muller, J. Y., additional, Bux, J., additional, Reil, A., additional, Lin, C. K., additional, Daly, H., additional, McSweeney, E., additional, Porretti, L., additional, Greppi, N., additional, Rebulla, P., additional, Okazaki, H., additional, Sánchez-Guerrero, S. A., additional, Baptista-González, H. A., additional, Martínez-Murillo, C., additional, Guerra-Márquez, A., additional, Rodriguez-Moyado, H., additional, Middelburg, R. A., additional, Wiersum-Osselton, J. C., additional, Brand, A., additional, van Tilburg, C., additional, Dinesh, D., additional, Dagger, J., additional, Dunn, P., additional, Brojer, E., additional, Letowska, M., additional, Maslanka, K., additional, Lachert, E., additional, Uhrynowska, M., additional, Zhiburt, E., additional, Palfi, M., additional, Berlin, G., additional, Frey, B. M., additional, Puig Rovira, L., additional, Muñiz-Diaz, E., additional, Castro, E., additional, Chapman, C., additional, Green, A., additional, Massey, E., additional, Win, N., additional, Williamson, L., additional, Silliman, C. C., additional, Chaffin, D. J., additional, Ambruso, D. R., additional, Blumberg, N., additional, Tomasulo, P., additional, Land, K. J., additional, Norris, P. J., additional, Illoh, O. C., additional, Davey, R. J., additional, Benjamin, R. J., additional, Eder, A. F., additional, McLaughlin, L., additional, Kleinman, S., additional, and Panzer, S., additional

Published
2012
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36. A novel, orally active LPA 1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model

Author

Swaney, JS, primary, Chapman, C, additional, Correa, LD, additional, Stebbins, KJ, additional, Bundey, RA, additional, Prodanovich, PC, additional, Fagan, P, additional, Baccei, CS, additional, Santini, AM, additional, Hutchinson, JH, additional, Seiders, TJ, additional, Parr, TA, additional, Prasit, P, additional, Evans, JF, additional, and Lorrain, DS, additional

Published
2010
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45. Antenatal testing for haemoglobinopathies

Author

Old Jm, R. Amos, Bareford D, Chapman C, Barbara J. Bain, Wild Bj, and Davies Sc

Subjects
medicine.medical_specialty, Obstetrics, business.industry, Antenatal testing, medicine, Hematology, business
Published
2001

47. B-CLL WITH SURFACE IgMk PHENOTYPE

Author

Ferrant, A., primary, Doyen, C., additional, Bosly, A., additional, Delannoy, A., additional, Cornu, G., additional, Michaux, J. L., additional, Chapman, C. S., additional, Gooch, M. E., additional, Shaw, D. E., additional, and Campbell, A. C., additional

Published
2008
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