1. Antipsychotic medication and marked hyperprolactinaemia: iatros or true prolactinoma?
- Author
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Fergus J. Cameron, IH Koves, and F. C. Jarman
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,Adenoma ,business.industry ,medicine.medical_treatment ,Hyperprolactinaemia ,Magnetic resonance imaging ,General Medicine ,Serum prolactin level ,medicine.disease ,Prolactin ,Endocrinology ,El Niño ,Internal medicine ,Pediatrics, Perinatology and Child Health ,medicine ,Antipsychotic ,business ,Prolactinoma - Abstract
AIM To demonstrate that hyperprolactinaemia and/or prolactinoma occur in association with antipsychotic medication use. METHODS Three case studies of patients with markedly elevated serum prolactin level (>132 microg/l); either antipsychotic medication induced or as a consequence of a prolactinoma. CONCLUSION The management and investigation of children with markedly elevated serum prolactin levels remains poorly defined. In our case series, two patients were found to have prolactinomas. We suggest that paediatric patients with serum prolactin level above 50 microg/l in males and 70 microg/l in females, regardless of any antipsychotic medication use, receive magnetic resonance imaging to exclude prolactinoma.
- Published
- 2007
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